D-lyxose ketol-isomerase

D-lyxose ketol-isomerase
D-lyxose ketol-isomerase
Identifiers
EC number 5.3.1.15
CAS number 37318-42-6
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a D-lyxose ketol-isomerase (EC 5.3.1.15) is an enzyme that catalyzes the chemical reaction

D-lyxose \rightleftharpoons D-xylulose

Hence, this enzyme has one substrate, D-lyxose, and one product, D-xylulose.

This enzyme belongs to the family of isomerases, specifically those intramolecular oxidoreductases interconverting aldoses and ketoses. The systematic name of this enzyme class is D-lyxose aldose-ketose-isomerase. Other names in common use include D-lyxose isomerase, and D-lyxose ketol-isomerase. This enzyme participates in pentose and glucuronate interconversions.

Structural studies

As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 1QO2 and 1VZW.

References

  • ANDERSON RL, ALLISON DP (1965). "PURIFICATION AND CHARACTERIZATION OF D-LYXOSE ISOMERASE". J. Biol. Chem. 240: 2367–72. PMID 14304839. 
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