Meclonazepam

Meclonazepam
Meclonazepam
Systematic (IUPAC) name
(3S)-5-(2-chlorophenyl)-3-methyl-7-nitro-1,3-dihydro-2H-1,4-benzodiazepin-2-one
Clinical data
Pregnancy cat.  ?
Legal status  ?
Identifiers
CAS number 58662-84-3 N
ATC code None
PubChem CID 3033985
ChemSpider 2298544 YesY
UNII RN43209SMA YesY
ChEMBL CHEMBL351821 N
Chemical data
Formula C16H12ClN3O3 
Mol. mass 329.74
SMILES eMolecules & PubChem
 N(what is this?)  (verify)

Meclonazepam ((S)-3-methylclonazepam) is a drug which is a benzodiazepine derivative similar in structure to clonazepam.[1] It has sedative and anxiolytic actions like those of other benzodiazepines,[1] and also has anti-parasitic effects against the parasitic worm Schistosoma mansoni.[2]

See also

References

  1. ^ Ansseau, M.; Doumont, A.; Thiry, D.; Von Frenckell, R.; Collard, J. (1985). "Initial study of methylclonazepam in generalized anxiety disorder. Evidence for greater power in the cross-over design". Psychopharmacology 87 (2): 130–135. PMID 3931136.  edit
  2. ^ O'Boyle, C.; Lambe, R.; Darragh, A. (1985). "Central effects in man of the novel schistosomicidal benzodiazepine meclonazepam". European journal of clinical pharmacology 29 (1): 105–108. PMID 4054198.  edit

Further reading

  • Abdul-Ghani, R. A.; Loutfy, N.; Hassan, A. (2009). "Experimentally promising antischistosomal drugs: A review of some drug candidates not reaching the clinical use". Parasitology Research 105 (4): 899–906. doi:10.1007/s00436-009-1546-2. PMID 19588166.  edit