Asparaginyl-tRNA synthase (glutamine-hydrolysing)


Asparaginyl-tRNA synthase (glutamine-hydrolysing)

In enzymology, an asparaginyl-tRNA synthase (glutamine-hydrolysing) (EC number|6.3.5.6) is an enzyme that catalyzes the chemical reaction

:ATP + aspartyl-tRNAAsn + L-glutamine ightleftharpoons ADP + phosphate + asparaginyl-tRNAAsn + L-glutamate

The 3 substrates of this enzyme are ATP, aspartyl-tRNA(Asn), and L-glutamine, whereas its 4 products are ADP, phosphate, asparaginyl-tRNA(Asn), and L-glutamate.

This enzyme belongs to the family of ligases, specifically those forming carbon-nitrogen bonds carbon-nitrogen ligases with glutamine as amido-N-donor. The systematic name of this enzyme class is aspartyl-tRNAAsn:L-glutamine amido-ligase (ADP-forming). Other names in common use include Asp-AdT, Asp-tRNAAsn amidotransferase, aspartyl-tRNAAsn amidotransferase, and Asn-tRNAAsn:L-glutamine amido-ligase (ADP-forming). This enzyme participates in glutamate metabolism and alanine and aspartate metabolism.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|37211-76-0."

Gene Ontology (GO) codes


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Look at other dictionaries:

  • List of EC numbers (EC 6) — This list contains a list of EC numbers for the sixth group, EC 6, ligases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 6.1: Forming Carbon Oxygen… …   Wikipedia


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