3'(2'),5'-bisphosphate nucleotidase

3'(2'),5'-bisphosphate nucleotidase

In enzymology, a 3'(2'),5'-bisphosphate nucleotidase (EC number|3.1.3.7) is an enzyme that catalyzes the chemical reaction

:adenosine 3',5'-bisphosphate + H2O ightleftharpoons adenosine 5'-phosphate + phosphate

Thus, the two substrates of this enzyme are adenosine 3',5'-bisphosphate and H2O, whereas its two products are adenosine 5'-phosphate and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name of this enzyme class is adenosine-3'(2'),5'-bisphosphate 3'(2')-phosphohydrolase. Other names in common use include phosphoadenylate 3'-nucleotidase, 3'-phosphoadenylylsulfate 3'-phosphatase, phosphoadenylate 3'-nucleotidase, and 3'(2'),5'-bisphosphonucleoside 3'(2')-phosphohydrolase. This enzyme participates in sulfur metabolism.

tructural studies

As of late 2007, 6 structures have been solved for this class of enzymes, with PDB accession codes PDB link|1JP4, PDB link|1K9Y, PDB link|1K9Z, PDB link|1KA0, PDB link|1KA1, and PDB link|1QGX.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|9025-83-6."

Gene Ontology (GO) codes


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