ADAMTS5

ADAMTS5

protein
Name = ADAM metallopeptidase with thrombospondin type 1 motif, 5 (aggrecanase-2)
caption =


width =
HGNCid = 221
Symbol = ADAMTS5
AltSymbols =
EntrezGene = 11096
OMIM = 605007
RefSeq = NM_007038
UniProt = Q9UNA0
PDB =
ECnumber =
Chromosome = 21
Arm = q
Band = 22.1
LocusSupplementaryData = -q22

ADAMTS5 (aggrecanase) is an enzyme that destroys cartilage in mice. Its discovery may lead to progress in human arthritis research. This enzyme may also be involved in cartilage deterioration in humans. It has been isolated and identified by Australian scientists in Sydney. ADAMTS5 has been indicated as being important in early osteoarthritis.

External links

* [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=304135 Rat Genome Database]


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