ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)
Symbols ELAVL1; ELAV1; HUR; Hua; MelG
External IDs OMIM603466 MGI1100851 HomoloGene20367 GeneCards: ELAVL1 Gene
RNA expression pattern
PBB GE ELAVL1 201726 at tn.png
PBB GE ELAVL1 201727 s at tn.png
More reference expression data
Species Human Mouse
Entrez 1994 15568
Ensembl ENSG00000066044 ENSMUSG00000040028
UniProt Q15717 Q3TT05
RefSeq (mRNA) NM_001419 NM_010485.3
RefSeq (protein) NP_001410 NP_034615.2
Location (UCSC) Chr 19:
8.02 – 8.07 Mb
Chr 8:
4.28 – 4.33 Mb
PubMed search [1] [2]

ELAV-like protein 1 or HuR is a protein that in humans is encoded by the ELAVL1 gene.[1][2]

The protein encoded by this gene is a member of the ELAVL protein family. This encoded protein contains 3 RNA-binding domains and binds cis-acting AU-rich elements. It stabilizes mRNAs and thereby regulates gene expression.[3]


  1. ^ Ma WJ, Cheng S, Campbell C, Wright A, Furneaux H (Jun 1996). "Cloning and characterization of HuR, a ubiquitously expressed Elav-like protein". J Biol Chem 271 (14): 8144–8151. doi:10.1074/jbc.271.14.8144. PMID 8626503. 
  2. ^ Ma WJ, Furneaux H (Feb 1997). "Localization of the human HuR gene to chromosome 19p13.2". Hum Genet 99 (1): 32–33. doi:10.1007/s004390050305. PMID 9003489. 
  3. ^ "Entrez Gene: ELAVL1 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1994. 

See Also

RNA-Binding Protein

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

Wikimedia Foundation. 2010.

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”

We are using cookies for the best presentation of our site. Continuing to use this site, you agree with this.