MAD2L1

MAD2 mitotic arrest deficient-like 1 (yeast), also known as MAD2L1, is a human gene.cite web | title = Entrez Gene: MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4085| accessdate = ]

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summary_text = MAD2L1 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. MAD2L1 is related to the MAD2L2 gene located on chromosome 1. A MAD2 pseudogene has been mapped to chromosome 14.cite web | title = Entrez Gene: MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4085| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Li Y, Benezra R |title=Identification of a human mitotic checkpoint gene: hsMAD2. |journal=Science |volume=274 |issue= 5285 |pages= 246–8 |year= 1996 |pmid= 8824189 |doi=
*cite journal | author=O'Neill TJ, Zhu Y, Gustafson TA |title=Interaction of MAD2 with the carboxyl terminus of the insulin receptor but not with the IGFIR. Evidence for release from the insulin receptor after activation. |journal=J. Biol. Chem. |volume=272 |issue= 15 |pages= 10035–40 |year= 1997 |pmid= 9092546 |doi=
*cite journal | author=Xu L, Deng HX, Yang Y, "et al." |title=Assignment of mitotic arrest deficient protein 2 (MAD2L1) to human chromosome band 5q23.3 by in situ hybridization. |journal=Cytogenet. Cell Genet. |volume=78 |issue= 1 |pages= 63–4 |year= 1997 |pmid= 9345911 |doi=
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Jin DY, Spencer F, Jeang KT |title=Human T cell leukemia virus type 1 oncoprotein Tax targets the human mitotic checkpoint protein MAD1. |journal=Cell |volume=93 |issue= 1 |pages= 81–91 |year= 1998 |pmid= 9546394 |doi=
*cite journal | author=Krishnan R, Goodman B, Jin DY, "et al." |title=Map location and gene structure of the Homo sapiens mitotic arrest deficient 2 (MAD2L1) gene at 4q27. |journal=Genomics |volume=49 |issue= 3 |pages= 475–8 |year= 1998 |pmid= 9615237 |doi= 10.1006/geno.1998.5233
*cite journal | author=Kallio M, Weinstein J, Daum JR, "et al." |title=Mammalian p55CDC mediates association of the spindle checkpoint protein Mad2 with the cyclosome/anaphase-promoting complex, and is involved in regulating anaphase onset and late mitotic events. |journal=J. Cell Biol. |volume=141 |issue= 6 |pages= 1393–406 |year= 1998 |pmid= 9628895 |doi=
*cite journal | author=Fang G, Yu H, Kirschner MW |title=The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation. |journal=Genes Dev. |volume=12 |issue= 12 |pages= 1871–83 |year= 1998 |pmid= 9637688 |doi=
*cite journal | author=Wassmann K, Benezra R |title=Mad2 transiently associates with an APC/p55Cdc complex during mitosis. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=95 |issue= 19 |pages= 11193–8 |year= 1998 |pmid= 9736712 |doi=
*cite journal | author=Liu YC, Pan J, Zhang C, "et al." |title=A MHC-encoded ubiquitin-like protein (FAT10) binds noncovalently to the spindle assembly checkpoint protein MAD2. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=96 |issue= 8 |pages= 4313–8 |year= 1999 |pmid= 10200259 |doi=
*cite journal | author=Cahill DP, da Costa LT, Carson-Walter EB, "et al." |title=Characterization of MAD2B and other mitotic spindle checkpoint genes. |journal=Genomics |volume=58 |issue= 2 |pages= 181–7 |year= 1999 |pmid= 10366450 |doi= 10.1006/geno.1999.5831
*cite journal | author=Nelson KK, Schlöndorff J, Blobel CP |title=Evidence for an interaction of the metalloprotease-disintegrin tumour necrosis factor alpha convertase (TACE) with mitotic arrest deficient 2 (MAD2), and of the metalloprotease-disintegrin MDC9 with a novel MAD2-related protein, MAD2beta. |journal=Biochem. J. |volume=343 Pt 3 |issue= |pages= 673–80 |year= 2000 |pmid= 10527948 |doi=
*cite journal | author=Murakumo Y, Roth T, Ishii H, "et al." |title=A human REV7 homolog that interacts with the polymerase zeta catalytic subunit hREV3 and the spindle assembly checkpoint protein hMAD2. |journal=J. Biol. Chem. |volume=275 |issue= 6 |pages= 4391–7 |year= 2000 |pmid= 10660610 |doi=
*cite journal | author=Luo X, Fang G, Coldiron M, "et al." |title=Structure of the Mad2 spindle assembly checkpoint protein and its interaction with Cdc20. |journal=Nat. Struct. Biol. |volume=7 |issue= 3 |pages= 224–9 |year= 2000 |pmid= 10700282 |doi= 10.1038/73338
*cite journal | author=Poelzl G, Kasai Y, Mochizuki N, "et al." |title=Specific association of estrogen receptor beta with the cell cycle spindle assembly checkpoint protein, MAD2. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=97 |issue= 6 |pages= 2836–9 |year= 2000 |pmid= 10706629 |doi= 10.1073/pnas.050580997
*cite journal | author=Steuerwald N, Cohen J, Herrera RJ, "et al." |title=Association between spindle assembly checkpoint expression and maternal age in human oocytes. |journal=Mol. Hum. Reprod. |volume=7 |issue= 1 |pages= 49–55 |year= 2001 |pmid= 11134360 |doi=
*cite journal | author=Campbell MS, Chan GK, Yen TJ |title=Mitotic checkpoint proteins HsMAD1 and HsMAD2 are associated with nuclear pore complexes in interphase. |journal=J. Cell. Sci. |volume=114 |issue= Pt 5 |pages= 953–63 |year= 2001 |pmid= 11181178 |doi=
*cite journal | author=Zhang Y, Lees E |title=Identification of an overlapping binding domain on Cdc20 for Mad2 and anaphase-promoting complex: model for spindle checkpoint regulation. |journal=Mol. Cell. Biol. |volume=21 |issue= 15 |pages= 5190–9 |year= 2001 |pmid= 11438673 |doi= 10.1128/MCB.21.15.5190-5199.2001
*cite journal | author=Sudakin V, Chan GK, Yen TJ |title=Checkpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2. |journal=J. Cell Biol. |volume=154 |issue= 5 |pages= 925–36 |year= 2001 |pmid= 11535616 |doi= 10.1083/jcb.200102093

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