GNB1

GNB1

Guanine nucleotide binding protein (G protein), beta polypeptide 1, also known as GNB1, is a human gene.cite web | title = Entrez Gene: GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2782| accessdate = ]

PBB_Summary
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summary_text = Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. This gene uses alternative polyadenylation signals.cite web | title = Entrez Gene: GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2782| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Downes GB, Gautam N |title=The G protein subunit gene families. |journal=Genomics |volume=62 |issue= 3 |pages= 544–52 |year= 2000 |pmid= 10644457 |doi= 10.1006/geno.1999.5992
*cite journal | author=Levine MA, Modi WS, O'Brien SJ |title=Chromosomal localization of the genes encoding two forms of the G protein beta polypeptide, beta 1 and beta 3, in man. |journal=Genomics |volume=8 |issue= 2 |pages= 380–6 |year= 1991 |pmid= 1979057 |doi=
*cite journal | author=Codina J, Stengel D, Woo SL, Birnbaumer L |title=Beta-subunits of the human liver Gs/Gi signal-transducing proteins and those of bovine retinal rod cell transducin are identical. |journal=FEBS Lett. |volume=207 |issue= 2 |pages= 187–92 |year= 1986 |pmid= 3095147 |doi=
*cite journal | author=Buhl AM, Osawa S, Johnson GL |title=Mitogen-activated protein kinase activation requires two signal inputs from the human anaphylatoxin C5a receptor. |journal=J. Biol. Chem. |volume=270 |issue= 34 |pages= 19828–32 |year= 1995 |pmid= 7649993 |doi=
*cite journal | author=Ray K, Kunsch C, Bonner LM, Robishaw JD |title=Isolation of cDNA clones encoding eight different human G protein gamma subunits, including three novel forms designated the gamma 4, gamma 10, and gamma 11 subunits. |journal=J. Biol. Chem. |volume=270 |issue= 37 |pages= 21765–71 |year= 1995 |pmid= 7665596 |doi=
*cite journal | author=Kozasa T, Gilman AG |title=Purification of recombinant G proteins from Sf9 cells by hexahistidine tagging of associated subunits. Characterization of alpha 12 and inhibition of adenylyl cyclase by alpha z. |journal=J. Biol. Chem. |volume=270 |issue= 4 |pages= 1734–41 |year= 1995 |pmid= 7829508 |doi=
*cite journal | author=Tsukada S, Simon MI, Witte ON, Katz A |title=Binding of beta gamma subunits of heterotrimeric G proteins to the PH domain of Bruton tyrosine kinase. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=91 |issue= 23 |pages= 11256–60 |year= 1994 |pmid= 7972043 |doi=
*cite journal | author=Ueda N, Iñiguez-Lluhi JA, Lee E, "et al." |title=G protein beta gamma subunits. Simplified purification and properties of novel isoforms. |journal=J. Biol. Chem. |volume=269 |issue= 6 |pages= 4388–95 |year= 1994 |pmid= 8308009 |doi=
*cite journal | author=Wall MA, Coleman DE, Lee E, "et al." |title=The structure of the G protein heterotrimer Gi alpha 1 beta 1 gamma 2. |journal=Cell |volume=83 |issue= 6 |pages= 1047–58 |year= 1996 |pmid= 8521505 |doi=
*cite journal | author=Sondek J, Bohm A, Lambright DG, "et al." |title=Crystal structure of a G-protein beta gamma dimer at 2.1A resolution. |journal=Nature |volume=379 |issue= 6563 |pages= 369–74 |year= 1996 |pmid= 8552196 |doi= 10.1038/379369a0
*cite journal | author=Andersson B, Wentland MA, Ricafrente JY, "et al." |title=A "double adaptor" method for improved shotgun library construction. |journal=Anal. Biochem. |volume=236 |issue= 1 |pages= 107–13 |year= 1996 |pmid= 8619474 |doi= 10.1006/abio.1996.0138
*cite journal | author=Mattingly RR, Macara IG |title=Phosphorylation-dependent activation of the Ras-GRF/CDC25Mm exchange factor by muscarinic receptors and G-protein beta gamma subunits. |journal=Nature |volume=382 |issue= 6588 |pages= 268–72 |year= 1996 |pmid= 8717044 |doi= 10.1038/382268a0
*cite journal | author=De Waard M, Liu H, Walker D, "et al." |title=Direct binding of G-protein betagamma complex to voltage-dependent calcium channels. |journal=Nature |volume=385 |issue= 6615 |pages= 446–50 |year= 1997 |pmid= 9009193 |doi= 10.1038/385446a0
*cite journal | author=Huang CL, Jan YN, Jan LY |title=Binding of the G protein betagamma subunit to multiple regions of G protein-gated inward-rectifying K+ channels. |journal=FEBS Lett. |volume=405 |issue= 3 |pages= 291–8 |year= 1997 |pmid= 9108307 |doi=
*cite journal | author=Yu W, Andersson B, Worley KC, "et al." |title=Large-scale concatenation cDNA sequencing. |journal=Genome Res. |volume=7 |issue= 4 |pages= 353–8 |year= 1997 |pmid= 9110174 |doi=
*cite journal | author=Qin N, Platano D, Olcese R, "et al." |title=Direct interaction of gbetagamma with a C-terminal gbetagamma-binding domain of the Ca2+ channel alpha1 subunit is responsible for channel inhibition by G protein-coupled receptors. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=94 |issue= 16 |pages= 8866–71 |year= 1997 |pmid= 9238069 |doi=
*cite journal | author=Nishida K, Kaziro Y, Satoh T |title=Association of the proto-oncogene product dbl with G protein betagamma subunits. |journal=FEBS Lett. |volume=459 |issue= 2 |pages= 186–90 |year= 1999 |pmid= 10518015 |doi=
*cite journal | author=Huang L, Shanker YG, Dubauskaite J, "et al." |title=Ggamma13 colocalizes with gustducin in taste receptor cells and mediates IP3 responses to bitter denatonium. |journal=Nat. Neurosci. |volume=2 |issue= 12 |pages= 1055–62 |year= 2000 |pmid= 10570481 |doi= 10.1038/15981
*cite journal | author=Carman CV, Barak LS, Chen C, "et al." |title=Mutational analysis of Gbetagamma and phospholipid interaction with G protein-coupled receptor kinase 2. |journal=J. Biol. Chem. |volume=275 |issue= 14 |pages= 10443–52 |year= 2000 |pmid= 10744734 |doi=

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