PIM1

PIM1

Pim-1 oncogene, also known as PIM1, is a human gene.cite web | title = Entrez Gene: PIM1 pim-1 oncogene| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5292| accessdate = ]

PBB_Summary
section_title =
summary_text = The protooncogene PIM1 encodes a protein kinase upregulated in prostate cancer. [supplied by OMIM] cite web | title = Entrez Gene: PIM1 pim-1 oncogene| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5292| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Ragoussis J, Senger G, Mockridge I, "et al." |title=A testis-expressed Zn finger gene (ZNF76) in human 6p21.3 centromeric to the MHC is closely linked to the human homolog of the t-complex gene tcp-11. |journal=Genomics |volume=14 |issue= 3 |pages= 673–9 |year= 1992 |pmid= 1427894 |doi=
*cite journal | author=Saris CJ, Domen J, Berns A |title=The pim-1 oncogene encodes two related protein-serine/threonine kinases by alternative initiation at AUG and CUG. |journal=EMBO J. |volume=10 |issue= 3 |pages= 655–64 |year= 1991 |pmid= 1825810 |doi=
*cite journal | author=Reeves R, Spies GA, Kiefer M, "et al." |title=Primary structure of the putative human oncogene, pim-1. |journal=Gene |volume=90 |issue= 2 |pages= 303–7 |year= 1990 |pmid= 2205533 |doi=
*cite journal | author=Amson R, Sigaux F, Przedborski S, "et al." |title=The human protooncogene product p33pim is expressed during fetal hematopoiesis and in diverse leukemias. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=86 |issue= 22 |pages= 8857–61 |year= 1989 |pmid= 2682662 |doi=
*cite journal | author=Telerman A, Amson R, Zakut-Houri R, Givol D |title=Identification of the human pim-1 gene product as a 33-kilodalton cytoplasmic protein with tyrosine kinase activity. |journal=Mol. Cell. Biol. |volume=8 |issue= 4 |pages= 1498–503 |year= 1988 |pmid= 2837645 |doi=
*cite journal | author=Domen J, Von Lindern M, Hermans A, "et al." |title=Comparison of the human and mouse PIM-1 cDNAs: nucleotide sequence and immunological identification of the in vitro synthesized PIM-1 protein. |journal=Oncogene Res. |volume=1 |issue= 1 |pages= 103–12 |year= 1988 |pmid= 3329709 |doi=
*cite journal | author=Meeker TC, Nagarajan L, ar-Rushdi A, Croce CM |title=Cloning and characterization of the human PIM-1 gene: a putative oncogene related to the protein kinases. |journal=J. Cell. Biochem. |volume=35 |issue= 2 |pages= 105–12 |year= 1988 |pmid= 3429489 |doi= 10.1002/jcb.240350204
*cite journal | author=Zakut-Houri R, Hazum S, Givol D, Telerman A |title=The cDNA sequence and gene analysis of the human pim oncogene. |journal=Gene |volume=54 |issue= 1 |pages= 105–11 |year= 1987 |pmid= 3475233 |doi=
*cite journal | author=Leverson JD, Koskinen PJ, Orrico FC, "et al." |title=Pim-1 kinase and p100 cooperate to enhance c-Myb activity. |journal=Mol. Cell |volume=2 |issue= 4 |pages= 417–25 |year= 1998 |pmid= 9809063 |doi=
*cite journal | author=Mochizuki T, Kitanaka C, Noguchi K, "et al." |title=Physical and functional interactions between Pim-1 kinase and Cdc25A phosphatase. Implications for the Pim-1-mediated activation of the c-Myc signaling pathway. |journal=J. Biol. Chem. |volume=274 |issue= 26 |pages= 18659–66 |year= 1999 |pmid= 10373478 |doi=
*cite journal | author=Koike N, Maita H, Taira T, "et al." |title=Identification of heterochromatin protein 1 (HP1) as a phosphorylation target by Pim-1 kinase and the effect of phosphorylation on the transcriptional repression function of HP1(1). |journal=FEBS Lett. |volume=467 |issue= 1 |pages= 17–21 |year= 2000 |pmid= 10664448 |doi=
*cite journal | author=Maita H, Harada Y, Nagakubo D, "et al." |title=PAP-1, a novel target protein of phosphorylation by pim-1 kinase. |journal=Eur. J. Biochem. |volume=267 |issue= 16 |pages= 5168–78 |year= 2000 |pmid= 10931201 |doi=
*cite journal | author=Mizuno K, Shirogane T, Shinohara A, "et al." |title=Regulation of Pim-1 by Hsp90. |journal=Biochem. Biophys. Res. Commun. |volume=281 |issue= 3 |pages= 663–9 |year= 2001 |pmid= 11237709 |doi= 10.1006/bbrc.2001.4405
*cite journal | author=Parks WT, Frank DB, Huff C, "et al." |title=Sorting nexin 6, a novel SNX, interacts with the transforming growth factor-beta family of receptor serine-threonine kinases. |journal=J. Biol. Chem. |volume=276 |issue= 22 |pages= 19332–9 |year= 2001 |pmid= 11279102 |doi= 10.1074/jbc.M100606200
*cite journal | author=Wang Z, Bhattacharya N, Meyer MK, "et al." |title=Pim-1 negatively regulates the activity of PTP-U2S phosphatase and influences terminal differentiation and apoptosis of monoblastoid leukemia cells. |journal=Arch. Biochem. Biophys. |volume=390 |issue= 1 |pages= 9–18 |year= 2001 |pmid= 11368509 |doi= 10.1006/abbi.2001.2370
*cite journal | author=Pasqualucci L, Neumeister P, Goossens T, "et al." |title=Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas. |journal=Nature |volume=412 |issue= 6844 |pages= 341–6 |year= 2001 |pmid= 11460166 |doi= 10.1038/35085588
*cite journal | author=Ishibashi Y, Maita H, Yano M, "et al." |title=Pim-1 translocates sorting nexin 6/TRAF4-associated factor 2 from cytoplasm to nucleus. |journal=FEBS Lett. |volume=506 |issue= 1 |pages= 33–8 |year= 2001 |pmid= 11591366 |doi=
*cite journal | author=Rainio EM, Sandholm J, Koskinen PJ |title=Cutting edge: Transcriptional activity of NFATc1 is enhanced by the Pim-1 kinase. |journal=J. Immunol. |volume=168 |issue= 4 |pages= 1524–7 |year= 2002 |pmid= 11823475 |doi=
*cite journal | author=Nieborowska-Skorska M, Hoser G, Kossev P, "et al." |title=Complementary functions of the antiapoptotic protein A1 and serine/threonine kinase pim-1 in the BCR/ABL-mediated leukemogenesis. |journal=Blood |volume=99 |issue= 12 |pages= 4531–9 |year= 2002 |pmid= 12036885 |doi=
*cite journal | author=Bhattacharya N, Wang Z, Davitt C, "et al." |title=Pim-1 associates with protein complexes necessary for mitosis. |journal=Chromosoma |volume=111 |issue= 2 |pages= 80–95 |year= 2003 |pmid= 12111331 |doi= 10.1007/s00412-002-0192-6

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