ERCC5

ERCC5

Excision repair cross-complementing rodent repair deficiency, complementation group 5 (xeroderma pigmentosum, complementation group G (Cockayne syndrome)), also known as ERCC5, is a human gene.cite web | title = Entrez Gene: ERCC5 excision repair cross-complementing rodent repair deficiency, complementation group 5 (xeroderma pigmentosum, complementation group G (Cockayne syndrome))| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2073| accessdate = ]

PBB_Summary
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summary_text = Excision repair cross-complementing rodent repair deficiency, complementation group 5 (xeroderma pigmentosum, complementation group G) is involved in excision repair of UV-induced DNA damage. Mutations cause Cockayne syndrome, which is characterized by severe growth defects, mental retardation, and cachexia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been described, but the biological validity of all variants has not been determined.cite web | title = Entrez Gene: ERCC5 excision repair cross-complementing rodent repair deficiency, complementation group 5 (xeroderma pigmentosum, complementation group G (Cockayne syndrome))| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2073| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Miura M |title=Detection of chromatin-bound PCNA in mammalian cells and its use to study DNA excision repair. |journal=J. Radiat. Res. |volume=40 |issue= 1 |pages= 1–12 |year= 1999 |pmid= 10408173 |doi=
*cite journal | author=Cleaver JE, Thompson LH, Richardson AS, States JC |title=A summary of mutations in the UV-sensitive disorders: xeroderma pigmentosum, Cockayne syndrome, and trichothiodystrophy. |journal=Hum. Mutat. |volume=14 |issue= 1 |pages= 9–22 |year= 1999 |pmid= 10447254 |doi= 10.1002/(SICI)1098-1004(1999)14:1<9::AID-HUMU2>3.0.CO;2-6 |doilabel=10.1002/(SICI)1098-1004(1999)14:19::AID-HUMU23.0.CO;2-6
*cite journal | author=Takahashi E, Shiomi N, Shiomi T |title=Precise localization of the excision repair gene, ERCC5, to human chromosome 13q32.3-q33.1 by direct R-banding fluorescence in situ hybridization. |journal=Jpn. J. Cancer Res. |volume=83 |issue= 11 |pages= 1117–9 |year= 1993 |pmid= 1483924 |doi=
*cite journal | author=Mudgett JS, MacInnes MA |title=Isolation of the functional human excision repair gene ERCC5 by intercosmid recombination. |journal=Genomics |volume=8 |issue= 4 |pages= 623–33 |year= 1991 |pmid= 2276736 |doi=
*cite journal | author=Shiomi T, Harada Y, Saito T, "et al." |title=An ERCC5 gene with homology to yeast RAD2 is involved in group G xeroderma pigmentosum. |journal=Mutat. Res. |volume=314 |issue= 2 |pages= 167–75 |year= 1994 |pmid= 7510366 |doi=
*cite journal | author=Lehmann AR, Bootsma D, Clarkson SG, "et al." |title=Nomenclature of human DNA repair genes. |journal=Mutat. Res. |volume=315 |issue= 1 |pages= 41–2 |year= 1994 |pmid= 7517009 |doi=
*cite journal | author=Cloud KG, Shen B, Strniste GF, Park MS |title=XPG protein has a structure-specific endonuclease activity. |journal=Mutat. Res. |volume=347 |issue= 2 |pages= 55–60 |year= 1995 |pmid= 7651464 |doi=
*cite journal | author=Matsunaga T, Mu D, Park CH, "et al." |title=Human DNA repair excision nuclease. Analysis of the roles of the subunits involved in dual incisions by using anti-XPG and anti-ERCC1 antibodies. |journal=J. Biol. Chem. |volume=270 |issue= 35 |pages= 20862–9 |year= 1995 |pmid= 7657672 |doi=
*cite journal | author=Nouspikel T, Clarkson SG |title=Mutations that disable the DNA repair gene XPG in a xeroderma pigmentosum group G patient. |journal=Hum. Mol. Genet. |volume=3 |issue= 6 |pages= 963–7 |year= 1994 |pmid= 7951246 |doi=
*cite journal | author=Habraken Y, Sung P, Prakash L, Prakash S |title=Human xeroderma pigmentosum group G gene encodes a DNA endonuclease. |journal=Nucleic Acids Res. |volume=22 |issue= 16 |pages= 3312–6 |year= 1994 |pmid= 8078765 |doi=
*cite journal | author=Samec S, Jones TA, Corlet J, "et al." |title=The human gene for xeroderma pigmentosum complementation group G (XPG) maps to 13q33 by fluorescence in situ hybridization. |journal=Genomics |volume=21 |issue= 1 |pages= 283–5 |year= 1994 |pmid= 8088806 |doi= 10.1006/geno.1994.1261
*cite journal | author=O'Donovan A, Davies AA, Moggs JG, "et al." |title=XPG endonuclease makes the 3' incision in human DNA nucleotide excision repair. |journal=Nature |volume=371 |issue= 6496 |pages= 432–5 |year= 1994 |pmid= 8090225 |doi= 10.1038/371432a0
*cite journal | author=O'Donovan A, Scherly D, Clarkson SG, Wood RD |title=Isolation of active recombinant XPG protein, a human DNA repair endonuclease. |journal=J. Biol. Chem. |volume=269 |issue= 23 |pages= 15965–8 |year= 1994 |pmid= 8206890 |doi=
*cite journal | author=MacInnes MA, Dickson JA, Hernandez RR, "et al." |title=Human ERCC5 cDNA-cosmid complementation for excision repair and bipartite amino acid domains conserved with RAD proteins of Saccharomyces cerevisiae and Schizosaccharomyces pombe. |journal=Mol. Cell. Biol. |volume=13 |issue= 10 |pages= 6393–402 |year= 1993 |pmid= 8413238 |doi=
*cite journal | author=Scherly D, Nouspikel T, Corlet J, "et al." |title=Complementation of the DNA repair defect in xeroderma pigmentosum group G cells by a human cDNA related to yeast RAD2. |journal=Nature |volume=363 |issue= 6425 |pages= 182–5 |year= 1993 |pmid= 8483504 |doi= 10.1038/363182a0
*cite journal | author=O'Donovan A, Wood RD |title=Identical defects in DNA repair in xeroderma pigmentosum group G and rodent ERCC group 5. |journal=Nature |volume=363 |issue= 6425 |pages= 185–8 |year= 1993 |pmid= 8483505 |doi= 10.1038/363185a0
*cite journal | author=Iyer N, Reagan MS, Wu KJ, "et al." |title=Interactions involving the human RNA polymerase II transcription/nucleotide excision repair complex TFIIH, the nucleotide excision repair protein XPG, and Cockayne syndrome group B (CSB) protein. |journal=Biochemistry |volume=35 |issue= 7 |pages= 2157–67 |year= 1996 |pmid= 8652557 |doi= 10.1021/bi9524124
*cite journal | author=Park MS, Knauf JA, Pendergrass SH, "et al." |title=Ultraviolet-induced movement of the human DNA repair protein, Xeroderma pigmentosum type G, in the nucleus. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=93 |issue= 16 |pages= 8368–73 |year= 1996 |pmid= 8710877 |doi=
*cite journal | author=Cooper PK, Nouspikel T, Clarkson SG, Leadon SA |title=Defective transcription-coupled repair of oxidative base damage in Cockayne syndrome patients from XP group G. |journal=Science |volume=275 |issue= 5302 |pages= 990–3 |year= 1997 |pmid= 9020084 |doi=
*cite journal | author=Nouspikel T, Lalle P, Leadon SA, "et al." |title=A common mutational pattern in Cockayne syndrome patients from xeroderma pigmentosum group G: implications for a second XPG function. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=94 |issue= 7 |pages= 3116–21 |year= 1997 |pmid= 9096355 |doi=

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