TNFSF13

Tumor necrosis factor (ligand) superfamily, member 13, also known as TNFSF13, is a human gene.cite web | title = Entrez Gene: TNFSF13 tumor necrosis factor (ligand) superfamily, member 13| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8741| accessdate = ] TNFSF13 has also been designated CD256 (cluster of differentiation 256).

PBB_Summary
section_title =
summary_text = The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. This protein and its receptor are both found to be important for B cell development. In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such as TNFRSF6/FAS and TNFRSF14/HVEM. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.cite web | title = Entrez Gene: TNFSF13 tumor necrosis factor (ligand) superfamily, member 13| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8741| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Bossen C, Schneider P |title=BAFF, APRIL and their receptors: structure, function and signaling. |journal=Semin. Immunol. |volume=18 |issue= 5 |pages= 263–75 |year= 2007 |pmid= 16914324 |doi= 10.1016/j.smim.2006.04.006
*cite journal | author=Tangye SG, Bryant VL, Cuss AK, Good KL |title=BAFF, APRIL and human B cell disorders. |journal=Semin. Immunol. |volume=18 |issue= 5 |pages= 305–17 |year= 2007 |pmid= 16916610 |doi= 10.1016/j.smim.2006.04.004
*cite journal | author=Treml LS, Crowley JE, Cancro MP |title=BLyS receptor signatures resolve homeostatically independent compartments among naïve and antigen-experienced B cells. |journal=Semin. Immunol. |volume=18 |issue= 5 |pages= 297–304 |year= 2007 |pmid= 16919470 |doi= 10.1016/j.smim.2006.07.001
*cite journal | author=Mackay F, Leung H |title=The role of the BAFF/APRIL system on T cell function. |journal=Semin. Immunol. |volume=18 |issue= 5 |pages= 284–9 |year= 2007 |pmid= 16931039 |doi= 10.1016/j.smim.2006.04.005
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Hahne M, Kataoka T, Schröter M, "et al." |title=APRIL, a new ligand of the tumor necrosis factor family, stimulates tumor cell growth. |journal=J. Exp. Med. |volume=188 |issue= 6 |pages= 1185–90 |year= 1998 |pmid= 9743536 |doi=
*cite journal | author=Shu HB, Hu WH, Johnson H |title=TALL-1 is a novel member of the TNF family that is down-regulated by mitogens. |journal=J. Leukoc. Biol. |volume=65 |issue= 5 |pages= 680–3 |year= 1999 |pmid= 10331498 |doi=
*cite journal | author=Cousin P, Billotte J, Chaubert P, Shaw P |title=Physical map of 17p13 and the genes adjacent to p53. |journal=Genomics |volume=63 |issue= 1 |pages= 60–8 |year= 2000 |pmid= 10662545 |doi= 10.1006/geno.1999.6062
*cite journal | author=Kelly K, Manos E, Jensen G, "et al." |title=APRIL/TRDL-1, a tumor necrosis factor-like ligand, stimulates cell death. |journal=Cancer Res. |volume=60 |issue= 4 |pages= 1021–7 |year= 2000 |pmid= 10706119 |doi=
*cite journal | author=Wu Y, Bressette D, Carrell JA, "et al." |title=Tumor necrosis factor (TNF) receptor superfamily member TACI is a high affinity receptor for TNF family members APRIL and BLyS. |journal=J. Biol. Chem. |volume=275 |issue= 45 |pages= 35478–85 |year= 2001 |pmid= 10956646 |doi= 10.1074/jbc.M005224200
*cite journal | author=Yu G, Boone T, Delaney J, "et al." |title=APRIL and TALL-I and receptors BCMA and TACI: system for regulating humoral immunity. |journal=Nat. Immunol. |volume=1 |issue= 3 |pages= 252–6 |year= 2001 |pmid= 10973284 |doi= 10.1038/79802
*cite journal | author=Gallouzi IE, Brennan CM, Steitz JA |title=Protein ligands mediate the CRM1-dependent export of HuR in response to heat shock. |journal=RNA |volume=7 |issue= 9 |pages= 1348–61 |year= 2001 |pmid= 11565755 |doi=
*cite journal | author=López-Fraga M, Fernández R, Albar JP, Hahne M |title=Biologically active APRIL is secreted following intracellular processing in the Golgi apparatus by furin convertase. |journal=EMBO Rep. |volume=2 |issue= 10 |pages= 945–51 |year= 2002 |pmid= 11571266 |doi= 10.1093/embo-reports/kve198
*cite journal | author=Stein JV, López-Fraga M, Elustondo FA, "et al." |title=APRIL modulates B and T cell immunity. |journal=J. Clin. Invest. |volume=109 |issue= 12 |pages= 1587–98 |year= 2002 |pmid= 12070306 |doi=
*cite journal | author=Litinskiy MB, Nardelli B, Hilbert DM, "et al." |title=DCs induce CD40-independent immunoglobulin class switching through BLyS and APRIL. |journal=Nat. Immunol. |volume=3 |issue= 9 |pages= 822–9 |year= 2002 |pmid= 12154359 |doi= 10.1038/ni829
*cite journal | author=Roschke V, Sosnovtseva S, Ward CD, "et al." |title=BLyS and APRIL form biologically active heterotrimers that are expressed in patients with systemic immune-based rheumatic diseases. |journal=J. Immunol. |volume=169 |issue= 8 |pages= 4314–21 |year= 2002 |pmid= 12370363 |doi=
*cite journal | author=Pradet-Balade B, Medema JP, López-Fraga M, "et al." |title=An endogenous hybrid mRNA encodes TWE-PRIL, a functional cell surface TWEAK-APRIL fusion protein. |journal=EMBO J. |volume=21 |issue= 21 |pages= 5711–20 |year= 2002 |pmid= 12411489 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Clark HF, Gurney AL, Abaya E, "et al." |title=The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. |journal=Genome Res. |volume=13 |issue= 10 |pages= 2265–70 |year= 2003 |pmid= 12975309 |doi= 10.1101/gr.1293003

External links

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