Phosphatidylethanolamine binding protein 1

Phosphatidylethanolamine binding protein 1
Phosphatidylethanolamine binding protein 1

PDB rendering based on 1a44.
Identifiers
Symbols PEBP1; HCNP; PBP; PEBP; RKIP
External IDs OMIM604591 MGI1344408 HomoloGene37637 GeneCards: PEBP1 Gene
RNA expression pattern
PBB GE PEBP1 210825 s at tn.png
PBB GE PEBP1 211941 s at tn.png
PBB GE PEBP1 205353 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 5037 23980
Ensembl ENSG00000089220 ENSMUSG00000032959
UniProt P30086 Q3TGC5
RefSeq (mRNA) NM_002567.2 NM_018858.2
RefSeq (protein) NP_002558 NP_061346.2
Location (UCSC) Chr 12:
118.57 – 118.58 Mb
Chr 5:
117.73 – 117.74 Mb
PubMed search [1] [2]

Phosphatidylethanolamine-binding protein 1 is a protein that in humans is encoded by the PEBP1 gene.[1][2]


Interactions

Phosphatidylethanolamine binding protein 1 has been shown to interact with MAP2K1,[3] C-Raf[3] and MAPK1.[3]

References

  1. ^ Park S, Yeung ML, Beach S, Shields JM, Yeung KC (May 2005). "RKIP downregulates B-Raf kinase activity in melanoma cancer cells". Oncogene 24 (21): 3535–40. doi:10.1038/sj.onc.1208435. PMID 15782137. 
  2. ^ "Entrez Gene: PEBP1 phosphatidylethanolamine binding protein 1". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5037. 
  3. ^ a b c Yeung, K; Janosch P, McFerran B, Rose D W, Mischak H, Sedivy J M, Kolch W (May. 2000). "Mechanism of suppression of the Raf/MEK/extracellular signal-regulated kinase pathway by the raf kinase inhibitor protein". Mol. Cell. Biol. (UNITED STATES) 20 (9): 3079–85. doi:10.1128/MCB.20.9.3079-3085.2000. ISSN 0270-7306. PMC 85596. PMID 10757792. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=85596. 

Further reading


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