MEIS1

Meis homeobox 1, also known as MEIS1, is a human gene.cite web | title = Entrez Gene: MEIS1 Meis homeobox 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4211| accessdate = ]

PBB_Summary
section_title =
summary_text = Homeobox genes, of which the most well-characterized category is represented by the HOX genes, play a crucial role in normal development. In addition, several homeoproteins are involved in neoplasia. This gene encodes a homeobox protein belonging to the TALE ('three amino acid loop extension') family of homeodomain-containing proteins.cite web | title = Entrez Gene: MEIS1 Meis homeobox 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4211| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Allen TD, Zhu YX, Hawley TS, Hawley RG |title=TALE homeoproteins as HOX11-interacting partners in T-cell leukemia. |journal=Leuk. Lymphoma |volume=39 |issue= 3-4 |pages= 241–56 |year= 2001 |pmid= 11342305 |doi=
*cite journal | author=Moskow JJ, Bullrich F, Huebner K, "et al." |title=Meis1, a PBX1-related homeobox gene involved in myeloid leukemia in BXH-2 mice. |journal=Mol. Cell. Biol. |volume=15 |issue= 10 |pages= 5434–43 |year= 1995 |pmid= 7565694 |doi=
*cite journal | author=Bonaldo MF, Lennon G, Soares MB |title=Normalization and subtraction: two approaches to facilitate gene discovery. |journal=Genome Res. |volume=6 |issue= 9 |pages= 791–806 |year= 1997 |pmid= 8889548 |doi=
*cite journal | author=Steelman S, Moskow JJ, Muzynski K, "et al." |title=Identification of a conserved family of Meis1-related homeobox genes. |journal=Genome Res. |volume=7 |issue= 2 |pages= 142–56 |year= 1997 |pmid= 9049632 |doi=
*cite journal | author=Smith JE, Bollekens JA, Inghirami G, Takeshita K |title=Cloning and mapping of the MEIS1 gene, the human homolog of a murine leukemogenic gene. |journal=Genomics |volume=43 |issue= 1 |pages= 99–103 |year= 1997 |pmid= 9226379 |doi= 10.1006/geno.1997.4766
*cite journal | author=Shen WF, Montgomery JC, Rozenfeld S, "et al." |title=AbdB-like Hox proteins stabilize DNA binding by the Meis1 homeodomain proteins. |journal=Mol. Cell. Biol. |volume=17 |issue= 11 |pages= 6448–58 |year= 1997 |pmid= 9343407 |doi=
*cite journal | author=Knoepfler PS, Calvo KR, Chen H, "et al." |title=Meis1 and pKnox1 bind DNA cooperatively with Pbx1 utilizing an interaction surface disrupted in oncoprotein E2a-Pbx1. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=94 |issue= 26 |pages= 14553–8 |year= 1998 |pmid= 9405651 |doi=
*cite journal | author= |title=Toward a complete human genome sequence. |journal=Genome Res. |volume=8 |issue= 11 |pages= 1097–108 |year= 1999 |pmid= 9847074 |doi=
*cite journal | author=Shen WF, Rozenfeld S, Kwong A, "et al." |title=HOXA9 forms triple complexes with PBX2 and MEIS1 in myeloid cells. |journal=Mol. Cell. Biol. |volume=19 |issue= 4 |pages= 3051–61 |year= 1999 |pmid= 10082572 |doi=
*cite journal | author=Jacobs Y, Schnabel CA, Cleary ML |title=Trimeric association of Hox and TALE homeodomain proteins mediates Hoxb2 hindbrain enhancer activity. |journal=Mol. Cell. Biol. |volume=19 |issue= 7 |pages= 5134–42 |year= 1999 |pmid= 10373562 |doi=
*cite journal | author=Knoepfler PS, Bergstrom DA, Uetsuki T, "et al." |title=A conserved motif N-terminal to the DNA-binding domains of myogenic bHLH transcription factors mediates cooperative DNA binding with pbx-Meis1/Prep1. |journal=Nucleic Acids Res. |volume=27 |issue= 18 |pages= 3752–61 |year= 1999 |pmid= 10471746 |doi=
*cite journal | author=Shanmugam K, Green NC, Rambaldi I, "et al." |title=PBX and MEIS as non-DNA-binding partners in trimeric complexes with HOX proteins. |journal=Mol. Cell. Biol. |volume=19 |issue= 11 |pages= 7577–88 |year= 1999 |pmid= 10523646 |doi=
*cite journal | author=Spieker N, van Sluis P, Beitsma M, "et al." |title=The MEIS1 oncogene is highly expressed in neuroblastoma and amplified in cell line IMR32. |journal=Genomics |volume=71 |issue= 2 |pages= 214–21 |year= 2001 |pmid= 11161815 |doi= 10.1006/geno.2000.6408
*cite journal | author=Wang Y, Yin L, Hillgartner FB |title=The homeodomain proteins PBX and MEIS1 are accessory factors that enhance thyroid hormone regulation of the malic enzyme gene in hepatocytes. |journal=J. Biol. Chem. |volume=276 |issue= 26 |pages= 23838–48 |year= 2001 |pmid= 11331288 |doi= 10.1074/jbc.M102166200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Okada Y, Nagai R, Sato T, "et al." |title=Homeodomain proteins MEIS1 and PBXs regulate the lineage-specific transcription of the platelet factor 4 gene. |journal=Blood |volume=101 |issue= 12 |pages= 4748–56 |year= 2004 |pmid= 12609849 |doi= 10.1182/blood-2002-02-0380
*cite journal | author=Zeisig BB, Milne T, García-Cuéllar MP, "et al." |title=Hoxa9 and Meis1 are key targets for MLL-ENL-mediated cellular immortalization. |journal=Mol. Cell. Biol. |volume=24 |issue= 2 |pages= 617–28 |year= 2004 |pmid= 14701735 |doi=
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Pineault N, Abramovich C, Ohta H, Humphries RK |title=Differential and common leukemogenic potentials of multiple NUP98-Hox fusion proteins alone or with Meis1. |journal=Mol. Cell. Biol. |volume=24 |issue= 5 |pages= 1907–17 |year= 2004 |pmid= 14966272 |doi=

External links

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