CDC34

Cell division cycle 34 homolog ("S. cerevisiae"), also known as CDC34, is a human gene.cite web | title = Entrez Gene: CDC34 cell division cycle 34 homolog (S. cerevisiae)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=997| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene is a member of the ubiquitin-conjugating enzyme family. Ubiquitin-conjugating enzyme catalyzes the covalent attachment of ubiquitin to other proteins. This protein is a part of the large multiprotein complex, which is required for ubiquitin-mediated degradation of cell cycle G1 regulators, and for the initiation of DNA replication.cite web | title = Entrez Gene: CDC34 cell division cycle 34 homolog (S. cerevisiae)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=997| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=King RW, Deshaies RJ, Peters JM, Kirschner MW |title=How proteolysis drives the cell cycle. |journal=Science |volume=274 |issue= 5293 |pages= 1652–9 |year= 1997 |pmid= 8939846 |doi=
*cite journal | author=Pagano M |title=Cell cycle regulation by the ubiquitin pathway. |journal=FASEB J. |volume=11 |issue= 13 |pages= 1067–75 |year= 1997 |pmid= 9367342 |doi=
*cite journal | author=Plon SE, Leppig KA, Do HN, Groudine M |title=Cloning of the human homolog of the CDC34 cell cycle gene by complementation in yeast. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=90 |issue= 22 |pages= 10484–8 |year= 1993 |pmid= 8248134 |doi=
*cite journal | author=Lisztwan J, Marti A, Sutterlüty H, "et al." |title=Association of human CUL-1 and ubiquitin-conjugating enzyme CDC34 with the F-box protein p45(SKP2): evidence for evolutionary conservation in the subunit composition of the CDC34-SCF pathway. |journal=EMBO J. |volume=17 |issue= 2 |pages= 368–83 |year= 1998 |pmid= 9430629 |doi= 10.1093/emboj/17.2.368
*cite journal | author=Song A, Wang Q, Goebl MG, Harrington MA |title=Phosphorylation of nuclear MyoD is required for its rapid degradation. |journal=Mol. Cell. Biol. |volume=18 |issue= 9 |pages= 4994–9 |year= 1998 |pmid= 9710583 |doi=
*cite journal | author=Gonen H, Bercovich B, Orian A, "et al." |title=Identification of the ubiquitin carrier proteins, E2s, involved in signal-induced conjugation and subsequent degradation of IkappaBalpha. |journal=J. Biol. Chem. |volume=274 |issue= 21 |pages= 14823–30 |year= 1999 |pmid= 10329681 |doi=
*cite journal | author=Pati D, Meistrich ML, Plon SE |title=Human Cdc34 and Rad6B ubiquitin-conjugating enzymes target repressors of cyclic AMP-induced transcription for proteolysis. |journal=Mol. Cell. Biol. |volume=19 |issue= 7 |pages= 5001–13 |year= 1999 |pmid= 10373550 |doi=
*cite journal | author=Seol JH, Feldman RM, Zachariae W, "et al." |title=Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34. |journal=Genes Dev. |volume=13 |issue= 12 |pages= 1614–26 |year= 1999 |pmid= 10385629 |doi=
*cite journal | author=Read MA, Brownell JE, Gladysheva TB, "et al." |title=Nedd8 modification of cul-1 activates SCF(beta(TrCP))-dependent ubiquitination of IkappaBalpha. |journal=Mol. Cell. Biol. |volume=20 |issue= 7 |pages= 2326–33 |year= 2000 |pmid= 10713156 |doi=
*cite journal | author=Reymond F, Wirbelauer C, Krek W |title=Association of human ubiquitin-conjugating enzyme CDC34 with the mitotic spindle in anaphase. |journal=J. Cell. Sci. |volume=113 ( Pt 10) |issue= |pages= 1687–94 |year= 2000 |pmid= 10769200 |doi=
*cite journal | author=Charrasse S, Carena I, Brondani V, "et al." |title=Degradation of B-Myb by ubiquitin-mediated proteolysis: involvement of the Cdc34-SCF(p45Skp2) pathway. |journal=Oncogene |volume=19 |issue= 26 |pages= 2986–95 |year= 2000 |pmid= 10871850 |doi= 10.1038/sj.onc.1203618
*cite journal | author=Strack P, Caligiuri M, Pelletier M, "et al." |title=SCF(beta-TRCP) and phosphorylation dependent ubiquitinationof I kappa B alpha catalyzed by Ubc3 and Ubc4. |journal=Oncogene |volume=19 |issue= 31 |pages= 3529–36 |year= 2000 |pmid= 10918611 |doi= 10.1038/sj.onc.1203647
*cite journal | author=Duan W, Sun B, Li TW, "et al." |title=Cloning and characterization of AWP1, a novel protein that associates with serine/threonine kinase PRK1 in vivo. |journal=Gene |volume=256 |issue= 1-2 |pages= 113–21 |year= 2001 |pmid= 11054541 |doi=
*cite journal | author=Block K, Boyer TG, Yew PR |title=Phosphorylation of the human ubiquitin-conjugating enzyme, CDC34, by casein kinase 2. |journal=J. Biol. Chem. |volume=276 |issue= 44 |pages= 41049–58 |year= 2001 |pmid= 11546811 |doi= 10.1074/jbc.M106453200
*cite journal | author=Wu K, Chen A, Tan P, Pan ZQ |title=The Nedd8-conjugated ROC1-CUL1 core ubiquitin ligase utilizes Nedd8 charged surface residues for efficient polyubiquitin chain assembly catalyzed by Cdc34. |journal=J. Biol. Chem. |volume=277 |issue= 1 |pages= 516–27 |year= 2002 |pmid= 11675391 |doi= 10.1074/jbc.M108008200
*cite journal | author=Kiernan RE, Emiliani S, Nakayama K, "et al." |title=Interaction between cyclin T1 and SCF(SKP2) targets CDK9 for ubiquitination and degradation by the proteasome. |journal=Mol. Cell. Biol. |volume=21 |issue= 23 |pages= 7956–70 |year= 2001 |pmid= 11689688 |doi= 10.1128/MCB.21.23.7956-7970.2001
*cite journal | author=Semplici F, Meggio F, Pinna LA, Oliviero S |title=CK2-dependent phosphorylation of the E2 ubiquitin conjugating enzyme UBC3B induces its interaction with beta-TrCP and enhances beta-catenin degradation. |journal=Oncogene |volume=21 |issue= 25 |pages= 3978–87 |year= 2002 |pmid= 12037680 |doi= 10.1038/sj.onc.1205574
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899

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