[cite web | title = Entrez Gene: EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9451| accessdate = ] ] PBB_Summary
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References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Mellor H, Proud CG |title=A synthetic peptide substrate for initiation factor-2 kinases. |journal=Biochem. Biophys. Res. Commun. |volume=178 |issue= 2 |pages= 430–7 |year= 1991 |pmid= 1677563 |doi=
*cite journal | author=Dever TE, Chen JJ, Barber GN, "et al." |title=Mammalian eukaryotic initiation factor 2 alpha kinases functionally substitute for GCN2 protein kinase in the GCN4 translational control mechanism of yeast. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=90 |issue= 10 |pages= 4616–20 |year= 1993 |pmid= 8099443 |doi=
*cite journal | author=Shi Y, Vattem KM, Sood R, "et al." |title=Identification and characterization of pancreatic eukaryotic initiation factor 2 alpha-subunit kinase, PEK, involved in translational control. |journal=Mol. Cell. Biol. |volume=18 |issue= 12 |pages= 7499–509 |year= 1998 |pmid= 9819435 |doi=
*cite journal | author=Shi Y, An J, Liang J, "et al." |title=Characterization of a mutant pancreatic eIF-2alpha kinase, PEK, and co-localization with somatostatin in islet delta cells. |journal=J. Biol. Chem. |volume=274 |issue= 9 |pages= 5723–30 |year= 1999 |pmid= 10026192 |doi=
*cite journal | author=Hayes SE, Conner LJ, Stramm LE, Shi Y |title=Assignment of pancreatic eIF-2alpha kinase (EIF2AK3) to human chromosome band 2p12 by radiation hybrid mapping and in situ hybridization. |journal=Cytogenet. Cell Genet. |volume=86 |issue= 3-4 |pages= 327–8 |year= 2000 |pmid= 10575235 |doi=
*cite journal | author=Sood R, Porter AC, Ma K, "et al." |title=Pancreatic eukaryotic initiation factor-2alpha kinase (PEK) homologues in humans, Drosophila melanogaster and Caenorhabditis elegans that mediate translational control in response to endoplasmic reticulum stress. |journal=Biochem. J. |volume=346 Pt 2 |issue= |pages= 281–93 |year= 2000 |pmid= 10677345 |doi=
*cite journal | author=Delépine M, Nicolino M, Barrett T, "et al." |title=EIF2AK3, encoding translation initiation factor 2-alpha kinase 3, is mutated in patients with Wolcott-Rallison syndrome. |journal=Nat. Genet. |volume=25 |issue= 4 |pages= 406–9 |year= 2000 |pmid= 10932183 |doi= 10.1038/78085
*cite journal | author=Saelens X, Kalai M, Vandenabeele P |title=Translation inhibition in apoptosis: caspase-dependent PKR activation and eIF2-alpha phosphorylation. |journal=J. Biol. Chem. |volume=276 |issue= 45 |pages= 41620–8 |year= 2001 |pmid= 11555640 |doi= 10.1074/jbc.M103674200
*cite journal | author=Ma K, Vattem KM, Wek RC |title=Dimerization and release of molecular chaperone inhibition facilitate activation of eukaryotic initiation factor-2 kinase in response to endoplasmic reticulum stress. |journal=J. Biol. Chem. |volume=277 |issue= 21 |pages= 18728–35 |year= 2002 |pmid= 11907036 |doi= 10.1074/jbc.M200903200
*cite journal | author=Okada T, Yoshida H, Akazawa R, "et al." |title=Distinct roles of activating transcription factor 6 (ATF6) and double-stranded RNA-activated protein kinase-like endoplasmic reticulum kinase (PERK) in transcription during the mammalian unfolded protein response. |journal=Biochem. J. |volume=366 |issue= Pt 2 |pages= 585–94 |year= 2002 |pmid= 12014989 |doi= 10.1042/BJ20020391
*cite journal | author=Biason-Lauber A, Lang-Muritano M, Vaccaro T, Schoenle EJ |title=Loss of kinase activity in a patient with Wolcott-Rallison syndrome caused by a novel mutation in the EIF2AK3 gene. |journal=Diabetes |volume=51 |issue= 7 |pages= 2301–5 |year= 2002 |pmid= 12086964 |doi=
*cite journal | author=Koumenis C, Naczki C, Koritzinsky M, "et al." |title=Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alpha. |journal=Mol. Cell. Biol. |volume=22 |issue= 21 |pages= 7405–16 |year= 2002 |pmid= 12370288 |doi=
*cite journal | author=Marcu MG, Doyle M, Bertolotti A, "et al." |title=Heat shock protein 90 modulates the unfolded protein response by stabilizing IRE1alpha. |journal=Mol. Cell. Biol. |volume=22 |issue= 24 |pages= 8506–13 |year= 2003 |pmid= 12446770 |doi=
*cite journal | author=Yan W, Frank CL, Korth MJ, "et al." |title=Control of PERK eIF2alpha kinase activity by the endoplasmic reticulum stress-induced molecular chaperone P58IPK. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 25 |pages= 15920–5 |year= 2003 |pmid= 12446838 |doi= 10.1073/pnas.252341799
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Pavio N, Romano PR, Graczyk TM, "et al." |title=Protein synthesis and endoplasmic reticulum stress can be modulated by the hepatitis C virus envelope protein E2 through the eukaryotic initiation factor 2alpha kinase PERK. |journal=J. Virol. |volume=77 |issue= 6 |pages= 3578–85 |year= 2003 |pmid= 12610133 |doi=
*cite journal | author=Cullinan SB, Zhang D, Hannink M, "et al." |title=Nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival. |journal=Mol. Cell. Biol. |volume=23 |issue= 20 |pages= 7198–209 |year= 2003 |pmid= 14517290 |doi=
*cite journal | author=Brandenberger R, Wei H, Zhang S, "et al." |title=Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. |journal=Nat. Biotechnol. |volume=22 |issue= 6 |pages= 707–16 |year= 2005 |pmid= 15146197 |doi= 10.1038/nbt971
*cite journal | author=Senée V, Vattem KM, Delépine M, "et al." |title=Wolcott-Rallison Syndrome: clinical, genetic, and functional study of EIF2AK3 mutations and suggestion of genetic heterogeneity. |journal=Diabetes |volume=53 |issue= 7 |pages= 1876–83 |year= 2004 |pmid= 15220213 |doi=
*cite journal | author=Allotey RA, Mohan V, McDermott MF, "et al." |title=The EIF2AK3 gene region and type I diabetes in subjects from South India. |journal=Genes Immun. |volume=5 |issue= 8 |pages= 648–52 |year= 2005 |pmid= 15483661 |doi= 10.1038/sj.gene.6364139
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