EPHA7

EPHA7

EPH receptor A7, also known as EPHA7, is a human gene.cite web | title = Entrez Gene: EPHA7 EPH receptor A7| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2045| accessdate = ]

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summary_text = This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.cite web | title = Entrez Gene: EPHA7 EPH receptor A7| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2045| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Flanagan JG, Vanderhaeghen P |title=The ephrins and Eph receptors in neural development. |journal=Annu. Rev. Neurosci. |volume=21 |issue= |pages= 309–45 |year= 1998 |pmid= 9530499 |doi= 10.1146/annurev.neuro.21.1.309
*cite journal | author=Zhou R |title=The Eph family receptors and ligands. |journal=Pharmacol. Ther. |volume=77 |issue= 3 |pages= 151–81 |year= 1998 |pmid= 9576626 |doi=
*cite journal | author=Holder N, Klein R |title=Eph receptors and ephrins: effectors of morphogenesis. |journal=Development |volume=126 |issue= 10 |pages= 2033–44 |year= 1999 |pmid= 10207129 |doi=
*cite journal | author=Wilkinson DG |title=Eph receptors and ephrins: regulators of guidance and assembly. |journal=Int. Rev. Cytol. |volume=196 |issue= |pages= 177–244 |year= 2000 |pmid= 10730216 |doi=
*cite journal | author=Xu Q, Mellitzer G, Wilkinson DG |title=Roles of Eph receptors and ephrins in segmental patterning. |journal=Philos. Trans. R. Soc. Lond., B, Biol. Sci. |volume=355 |issue= 1399 |pages= 993–1002 |year= 2001 |pmid= 11128993 |doi= 10.1098/rstb.2000.0635
*cite journal | author=Wilkinson DG |title=Multiple roles of EPH receptors and ephrins in neural development. |journal=Nat. Rev. Neurosci. |volume=2 |issue= 3 |pages= 155–64 |year= 2001 |pmid= 11256076 |doi=
*cite journal | author=Fox GM, Holst PL, Chute HT, "et al." |title=cDNA cloning and tissue distribution of five human EPH-like receptor protein-tyrosine kinases. |journal=Oncogene |volume=10 |issue= 5 |pages= 897–905 |year= 1995 |pmid= 7898931 |doi=
*cite journal | author=Gale NW, Holland SJ, Valenzuela DM, "et al." |title=Eph receptors and ligands comprise two major specificity subclasses and are reciprocally compartmentalized during embryogenesis. |journal=Neuron |volume=17 |issue= 1 |pages= 9–19 |year= 1996 |pmid= 8755474 |doi=
*cite journal | author=Bonaldo MF, Lennon G, Soares MB |title=Normalization and subtraction: two approaches to facilitate gene discovery. |journal=Genome Res. |volume=6 |issue= 9 |pages= 791–806 |year= 1997 |pmid= 8889548 |doi=
*cite journal | author=Ciossek T, Ullrich A |title=Identification of Elf-1 and B61 as high affinity ligands for the receptor tyrosine kinase MDK1. |journal=Oncogene |volume=14 |issue= 1 |pages= 35–43 |year= 1997 |pmid= 9010230 |doi= 10.1038/sj.onc.1200800
*cite journal | author= |title=Unified nomenclature for Eph family receptors and their ligands, the ephrins. Eph Nomenclature Committee. |journal=Cell |volume=90 |issue= 3 |pages= 403–4 |year= 1997 |pmid= 9267020 |doi=
*cite journal | author=Hock B, Böhme B, Karn T, "et al." |title=PDZ-domain-mediated interaction of the Eph-related receptor tyrosine kinase EphB3 and the ras-binding protein AF6 depends on the kinase activity of the receptor. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=95 |issue= 17 |pages= 9779–84 |year= 1998 |pmid= 9707552 |doi=
*cite journal | author=Bianchi LM, Liu H |title=Comparison of ephrin-A ligand and EphA receptor distribution in the developing inner ear. |journal=Anat. Rec. |volume=254 |issue= 1 |pages= 127–34 |year= 1999 |pmid= 9892426 |doi=
*cite journal | author=Janis LS, Cassidy RM, Kromer LF |title=Ephrin-A binding and EphA receptor expression delineate the matrix compartment of the striatum. |journal=J. Neurosci. |volume=19 |issue= 12 |pages= 4962–71 |year= 1999 |pmid= 10366629 |doi=
*cite journal | author=Stubbs J, Palmer A, Vidovic M, Marotte LR |title=Graded expression of EphA3 in the retina and ephrin-A2 in the superior colliculus during initial development of coarse topography in the wallaby retinocollicular projection. |journal=Eur. J. Neurosci. |volume=12 |issue= 10 |pages= 3626–36 |year= 2000 |pmid= 11029633 |doi=

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