FBLN2

Fibulin 2, also known as FBLN2, is a human gene.cite web | title = Entrez Gene: FBLN2 fibulin 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2199| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes an extracellular matrix protein, which belongs to the fibulin family. This protein binds various extracellular ligands and calcium. It may play a role during organ development, in particular, during the differentiation of heart, skeletal and neuronal structures. Alternatively spliced transcript variants encoding different isoforms have been identified.cite web | title = Entrez Gene: FBLN2 fibulin 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2199| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Sasaki T, Göhring W, Pan TC, "et al." |title=Binding of mouse and human fibulin-2 to extracellular matrix ligands. |journal=J. Mol. Biol. |volume=254 |issue= 5 |pages= 892–9 |year= 1996 |pmid= 7500359 |doi= 10.1006/jmbi.1995.0664
*cite journal | author=Zhang RZ, Pan TC, Zhang ZY, "et al." |title=Fibulin-2 (FBLN2): human cDNA sequence, mRNA expression, and mapping of the gene on human and mouse chromosomes. |journal=Genomics |volume=22 |issue= 2 |pages= 425–30 |year= 1995 |pmid= 7806230 |doi= 10.1006/geno.1994.1404
*cite journal | author=Pan TC, Sasaki T, Zhang RZ, "et al." |title=Structure and expression of fibulin-2, a novel extracellular matrix protein with multiple EGF-like repeats and consensus motifs for calcium binding. |journal=J. Cell Biol. |volume=123 |issue= 5 |pages= 1269–77 |year= 1994 |pmid= 8245130 |doi=
*cite journal | author=Reinhardt DP, Sasaki T, Dzamba BJ, "et al." |title=Fibrillin-1 and fibulin-2 interact and are colocalized in some tissues. |journal=J. Biol. Chem. |volume=271 |issue= 32 |pages= 19489–96 |year= 1996 |pmid= 8702639 |doi=
*cite journal | author=Miosge N, Götz W, Sasaki T, "et al." |title=The extracellular matrix proteins fibulin-1 and fibulin-2 in the early human embryo. |journal=Histochem. J. |volume=28 |issue= 2 |pages= 109–16 |year= 1996 |pmid= 8737292 |doi=
*cite journal | author=Collod G, Chu ML, Sasaki T, "et al." |title=Fibulin-2: genetic mapping and exclusion as a candidate gene in Marfan syndrome type 2. |journal=Eur. J. Hum. Genet. |volume=4 |issue= 5 |pages= 292–5 |year= 1997 |pmid= 8946175 |doi=
*cite journal | author=Utani A, Nomizu M, Yamada Y |title=Fibulin-2 binds to the short arms of laminin-5 and laminin-1 via conserved amino acid sequences. |journal=J. Biol. Chem. |volume=272 |issue= 5 |pages= 2814–20 |year= 1997 |pmid= 9006922 |doi=
*cite journal | author=Sasaki T, Mann K, Wiedemann H, "et al." |title=Dimer model for the microfibrillar protein fibulin-2 and identification of the connecting disulfide bridge. |journal=EMBO J. |volume=16 |issue= 11 |pages= 3035–43 |year= 1997 |pmid= 9214621 |doi= 10.1093/emboj/16.11.3035
*cite journal | author=Brown JC, Sasaki T, Göhring W, "et al." |title=The C-terminal domain V of perlecan promotes beta1 integrin-mediated cell adhesion, binds heparin, nidogen and fibulin-2 and can be modified by glycosaminoglycans. |journal=Eur. J. Biochem. |volume=250 |issue= 1 |pages= 39–46 |year= 1998 |pmid= 9431988 |doi=
*cite journal | author=Raghunath M, Tschödrich-Rotter M, Sasaki T, "et al." |title=Confocal laser scanning analysis of the association of fibulin-2 with fibrillin-1 and fibronectin define different stages of skin regeneration. |journal=J. Invest. Dermatol. |volume=112 |issue= 1 |pages= 97–101 |year= 1999 |pmid= 9886271 |doi= 10.1046/j.1523-1747.1999.00483.x
*cite journal | author=Kuivaniemi H, Marshall A, Ganguly A, "et al." |title=Fibulin-2 exhibits high degree of variability, but no structural changes concordant with abdominal aortic aneurysms. |journal=Eur. J. Hum. Genet. |volume=6 |issue= 6 |pages= 642–6 |year= 1999 |pmid= 9887386 |doi= 10.1038/sj.ejhg.5200245
*cite journal | author=Sasaki T, Göhring W, Miosge N, "et al." |title=Tropoelastin binding to fibulins, nidogen-2 and other extracellular matrix proteins. |journal=FEBS Lett. |volume=460 |issue= 2 |pages= 280–4 |year= 1999 |pmid= 10544250 |doi=
*cite journal | author=Gu YC, Nilsson K, Eng H, Ekblom M |title=Association of extracellular matrix proteins fibulin-1 and fibulin-2 with fibronectin in bone marrow stroma. |journal=Br. J. Haematol. |volume=109 |issue= 2 |pages= 305–13 |year= 2000 |pmid= 10848816 |doi=
*cite journal | author=Talts JF, Sasaki T, Miosge N, "et al." |title=Structural and functional analysis of the recombinant G domain of the laminin alpha4 chain and its proteolytic processing in tissues. |journal=J. Biol. Chem. |volume=275 |issue= 45 |pages= 35192–9 |year= 2001 |pmid= 10934193 |doi= 10.1074/jbc.M003261200
*cite journal | author=Olin AI, Mörgelin M, Sasaki T, "et al." |title=The proteoglycans aggrecan and Versican form networks with fibulin-2 through their lectin domain binding. |journal=J. Biol. Chem. |volume=276 |issue= 2 |pages= 1253–61 |year= 2001 |pmid= 11038354 |doi= 10.1074/jbc.M006783200
*cite journal | author=Hopf M, Göhring W, Mann K, Timpl R |title=Mapping of binding sites for nidogens, fibulin-2, fibronectin and heparin to different IG modules of perlecan. |journal=J. Mol. Biol. |volume=311 |issue= 3 |pages= 529–41 |year= 2001 |pmid= 11493006 |doi= 10.1006/jmbi.2001.4878
*cite journal | author=Hunzelmann N, Nischt R, Brenneisen P, "et al." |title=Increased deposition of fibulin-2 in solar elastosis and its colocalization with elastic fibres. |journal=Br. J. Dermatol. |volume=145 |issue= 2 |pages= 217–22 |year= 2001 |pmid= 11531782 |doi=
*cite journal | author=Sasaki T, Göhring W, Mann K, "et al." |title=Short arm region of laminin-5 gamma2 chain: structure, mechanism of processing and binding to heparin and proteins. |journal=J. Mol. Biol. |volume=314 |issue= 4 |pages= 751–63 |year= 2002 |pmid= 11733994 |doi= 10.1006/jmbi.2001.5176
*cite journal | author=Bengtsson E, Mörgelin M, Sasaki T, "et al." |title=The leucine-rich repeat protein PRELP binds perlecan and collagens and may function as a basement membrane anchor. |journal=J. Biol. Chem. |volume=277 |issue= 17 |pages= 15061–8 |year= 2002 |pmid= 11847210 |doi= 10.1074/jbc.M108285200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899

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