Hyaluronan-mediated motility receptor

Hyaluronan-mediated motility receptor (RHAMM), also known as HMMR, is a human gene.cite web | title = Entrez Gene: HMMR hyaluronan-mediated motility receptor (RHAMM)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3161| accessdate = ] RHAMM recently has been designated CD168 (cluster of differentiation 168).

PBB_Summary
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summary_text = The receptor for hyaluronan mediated motility has been reported to mediate migration, transformation, and metastatic spread of murine fibroblasts. In human, it is expressed as an intracellular protein in breast cancer cells. No correlation between the level of HMMR mRNA and protein expression with known metastatic/malignant potential of the tumour cell lines was observed.cite web | title = Entrez Gene: HMMR hyaluronan-mediated motility receptor (RHAMM)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3161| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Dawson SJ, White LA |title=Treatment of Haemophilus aphrophilus endocarditis with ciprofloxacin. |journal=J. Infect. |volume=24 |issue= 3 |pages= 317–20 |year= 1992 |pmid= 1602151 |doi=
*cite journal | author=Hall CL, Yang B, Yang X, "et al." |title=Overexpression of the hyaluronan receptor RHAMM is transforming and is also required for H-ras transformation. |journal=Cell |volume=82 |issue= 1 |pages= 19–26 |year= 1995 |pmid= 7541721 |doi=
*cite journal | author=Pilarski LM, Miszta H, Turley EA |title=Regulated expression of a receptor for hyaluronan-mediated motility on human thymocytes and T cells. |journal=J. Immunol. |volume=150 |issue= 10 |pages= 4292–302 |year= 1993 |pmid= 7683315 |doi=
*cite journal | author=Spicer AP, Roller ML, Camper SA, "et al." |title=The human and mouse receptors for hyaluronan-mediated motility, RHAMM, genes (HMMR) map to human chromosome 5q33.2-qter and mouse chromosome 11. |journal=Genomics |volume=30 |issue= 1 |pages= 115–7 |year= 1996 |pmid= 8595891 |doi= 10.1006/geno.1995.0022
*cite journal | author=Wang C, Entwistle J, Hou G, "et al." |title=The characterization of a human RHAMM cDNA: conservation of the hyaluronan-binding domains. |journal=Gene |volume=174 |issue= 2 |pages= 299–306 |year= 1996 |pmid= 8890751 |doi=
*cite journal | author=Assmann V, Marshall JF, Fieber C, "et al." |title=The human hyaluronan receptor RHAMM is expressed as an intracellular protein in breast cancer cells. |journal=J. Cell. Sci. |volume=111 ( Pt 12) |issue= |pages= 1685–94 |year= 1999 |pmid= 9601098 |doi=
*cite journal | author=Pilarski LM, Pruski E, Wizniak J, "et al." |title=Potential role for hyaluronan and the hyaluronan receptor RHAMM in mobilization and trafficking of hematopoietic progenitor cells. |journal=Blood |volume=93 |issue= 9 |pages= 2918–27 |year= 1999 |pmid= 10216086 |doi=
*cite journal | author=Assmann V, Jenkinson D, Marshall JF, Hart IR |title=The intracellular hyaluronan receptor RHAMM/IHABP interacts with microtubules and actin filaments. |journal=J. Cell. Sci. |volume=112 ( Pt 22) |issue= |pages= 3943–54 |year= 2000 |pmid= 10547355 |doi=
*cite journal | author=Lokeshwar VB, Selzer MG |title=Differences in hyaluronic acid-mediated functions and signaling in arterial, microvessel, and vein-derived human endothelial cells. |journal=J. Biol. Chem. |volume=275 |issue= 36 |pages= 27641–9 |year= 2000 |pmid= 10882722 |doi= 10.1074/jbc.M003084200
*cite journal | author=Lynn BD, Li X, Cattini PA, Nagy JI |title=Sequence, protein expression and extracellular-regulated kinase association of the hyaladherin RHAMM (receptor for hyaluronan mediated motility) in PC12 cells. |journal=Neurosci. Lett. |volume=306 |issue= 1-2 |pages= 49–52 |year= 2001 |pmid= 11403955 |doi=
*cite journal | author=Lynn BD, Turley EA, Nagy JI |title=Subcellular distribution, calmodulin interaction, and mitochondrial association of the hyaluronan-binding protein RHAMM in rat brain. |journal=J. Neurosci. Res. |volume=65 |issue= 1 |pages= 6–16 |year= 2001 |pmid= 11433424 |doi=
*cite journal | author=Savani RC, Cao G, Pooler PM, "et al." |title=Differential involvement of the hyaluronan (HA) receptors CD44 and receptor for HA-mediated motility in endothelial cell function and angiogenesis. |journal=J. Biol. Chem. |volume=276 |issue= 39 |pages= 36770–8 |year= 2001 |pmid= 11448954 |doi= 10.1074/jbc.M102273200
*cite journal | author=Akiyama Y, Jung S, Salhia B, "et al." |title=Hyaluronate receptors mediating glioma cell migration and proliferation. |journal=J. Neurooncol. |volume=53 |issue= 2 |pages= 115–27 |year= 2002 |pmid= 11716065 |doi=
*cite journal | author=Greiner J, Ringhoffer M, Taniguchi M, "et al." |title=Receptor for hyaluronan acid-mediated motility (RHAMM) is a new immunogenic leukemia-associated antigen in acute and chronic myeloid leukemia. |journal=Exp. Hematol. |volume=30 |issue= 9 |pages= 1029–35 |year= 2002 |pmid= 12225794 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Rein DT, Roehrig K, Schöndorf T, "et al." |title=Expression of the hyaluronan receptor RHAMM in endometrial carcinomas suggests a role in tumour progression and metastasis. |journal=J. Cancer Res. Clin. Oncol. |volume=129 |issue= 3 |pages= 161–4 |year= 2003 |pmid= 12712331 |doi= 10.1007/s00432-003-0415-0
*cite journal | author=Maxwell CA, Keats JJ, Crainie M, "et al." |title=RHAMM is a centrosomal protein that interacts with dynein and maintains spindle pole stability. |journal=Mol. Biol. Cell |volume=14 |issue= 6 |pages= 2262–76 |year= 2004 |pmid= 12808028 |doi= 10.1091/mbc.E02-07-0377
*cite journal | author=Aziz KA |title=CD44 mediates polymorphonuclear leukocyte motility on hyaluronan. |journal=Saudi medical journal |volume=24 |issue= 8 |pages= 827–31 |year= 2004 |pmid= 12939665 |doi=
*cite journal | author=Maxwell CA, Keats JJ, Belch AR, "et al." |title=Receptor for hyaluronan-mediated motility correlates with centrosome abnormalities in multiple myeloma and maintains mitotic integrity. |journal=Cancer Res. |volume=65 |issue= 3 |pages= 850–60 |year= 2005 |pmid= 15705883 |doi=
*cite journal | author=Yamasaki C, Tashiro S, Nishito Y, "et al." |title=Dynamic cytoplasmic anchoring of the transcription factor Bach1 by intracellular hyaluronic acid binding protein IHABP. |journal=J. Biochem. |volume=137 |issue= 3 |pages= 287–96 |year= 2005 |pmid= 15809329 |doi= 10.1093/jb/mvi031

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