MEP1A

MEP1A

Meprin A, alpha (PABA peptide hydrolase), also known as MEP1A, is a human gene.cite web | title = Entrez Gene: MEP1A meprin A, alpha (PABA peptide hydrolase)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4224| accessdate = ]

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References

Further reading

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*cite journal | author=Dumermuth E, Sterchi EE, Jiang WP, "et al." |title=The astacin family of metalloendopeptidases. |journal=J. Biol. Chem. |volume=266 |issue= 32 |pages= 21381–5 |year= 1991 |pmid= 1939172 |doi=
*cite journal | author=Kärgel HJ, Dettmer R, Etzold G, "et al." |title=Action of rat liver cathepsin L on glucagon. |journal=Acta Biol. Med. Ger. |volume=40 |issue= 9 |pages= 1139–43 |year= 1982 |pmid= 7340337 |doi=
*cite journal | author=Bond JS, Rojas K, Overhauser J, "et al." |title=The structural genes, MEP1A and MEP1B, for the alpha and beta subunits of the metalloendopeptidase meprin map to human chromosomes 6p and 18q, respectively. |journal=Genomics |volume=25 |issue= 1 |pages= 300–3 |year= 1995 |pmid= 7774936 |doi=
*cite journal | author=Kaushal GP, Walker PD, Shah SV |title=An old enzyme with a new function: purification and characterization of a distinct matrix-degrading metalloproteinase in rat kidney cortex and its identification as meprin. |journal=J. Cell Biol. |volume=126 |issue= 5 |pages= 1319–27 |year= 1994 |pmid= 8063866 |doi=
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Dumermuth E, Eldering JA, Grünberg J, "et al." |title=Cloning of the PABA peptide hydrolase alpha subunit (PPH alpha) from human small intestine and its expression in COS-1 cells. |journal=FEBS Lett. |volume=335 |issue= 3 |pages= 367–75 |year= 1994 |pmid= 8262185 |doi=
*cite journal | author=Bankus JM, Bond JS |title=Expression and distribution of meprin protease subunits in mouse intestine. |journal=Arch. Biochem. Biophys. |volume=331 |issue= 1 |pages= 87–94 |year= 1996 |pmid= 8660687 |doi= 10.1006/abbi.1996.0286
*cite journal | author=Chevallier S, Ahn J, Boileau G, Crine P |title=Identification of the cysteine residues implicated in the formation of alpha 2 and alpha/beta dimers of rat meprin. |journal=Biochem. J. |volume=317 ( Pt 3) |issue= |pages= 731–8 |year= 1996 |pmid= 8760356 |doi=
*cite journal | author=Eldering JA, Grünberg J, Hahn D, "et al." |title=Polarised expression of human intestinal N-benzoyl-L-tyrosyl-p-aminobenzoic acid hydrolase (human meprin) alpha and beta subunits in Madin-Darby canine kidney cells. |journal=Eur. J. Biochem. |volume=247 |issue= 3 |pages= 920–32 |year= 1997 |pmid= 9288916 |doi=
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Lottaz D, Hahn D, Müller S, "et al." |title=Secretion of human meprin from intestinal epithelial cells depends on differential expression of the alpha and beta subunits. |journal=Eur. J. Biochem. |volume=259 |issue= 1-2 |pages= 496–504 |year= 1999 |pmid= 9914532 |doi=
*cite journal | author=Richter R, Schulz-Knappe P, Schrader M, "et al." |title=Composition of the peptide fraction in human blood plasma: database of circulating human peptides. |journal=J. Chromatogr. B Biomed. Sci. Appl. |volume=726 |issue= 1-2 |pages= 25–35 |year= 1999 |pmid= 10348167 |doi=
*cite journal | author=Köhler D, Kruse M, Stöcker W, Sterchi EE |title=Heterologously overexpressed, affinity-purified human meprin alpha is functionally active and cleaves components of the basement membrane in vitro. |journal=FEBS Lett. |volume=465 |issue= 1 |pages= 2–7 |year= 2000 |pmid= 10620696 |doi=
*cite journal | author=Jiang W, Le B |title=Structure and expression of the human MEP1A gene encoding the alpha subunit of metalloendopeptidase meprin A. |journal=Arch. Biochem. Biophys. |volume=379 |issue= 2 |pages= 183–7 |year= 2000 |pmid= 10898933 |doi= 10.1006/abbi.2000.1873
*cite journal | author=Kumar JM, Bond JS |title=Developmental expression of meprin metalloprotease subunits in ICR and C3H/He mouse kidney and intestine in the embryo, postnatally and after weaning. |journal=Biochim. Biophys. Acta |volume=1518 |issue= 1-2 |pages= 106–14 |year= 2001 |pmid= 11267665 |doi=
*cite journal | author=Bertenshaw GP, Turk BE, Hubbard SJ, "et al." |title=Marked differences between metalloproteases meprin A and B in substrate and peptide bond specificity. |journal=J. Biol. Chem. |volume=276 |issue= 16 |pages= 13248–55 |year= 2001 |pmid= 11278902 |doi= 10.1074/jbc.M011414200
*cite journal | author=Ishmael FT, Norcum MT, Benkovic SJ, Bond JS |title=Multimeric structure of the secreted meprin A metalloproteinase and characterization of the functional protomer. |journal=J. Biol. Chem. |volume=276 |issue= 25 |pages= 23207–11 |year= 2001 |pmid= 11301339 |doi= 10.1074/jbc.M102654200
*cite journal | author=Rösmann S, Hahn D, Lottaz D, "et al." |title=Activation of human meprin-alpha in a cell culture model of colorectal cancer is triggered by the plasminogen-activating system. |journal=J. Biol. Chem. |volume=277 |issue= 43 |pages= 40650–8 |year= 2002 |pmid= 12189145 |doi= 10.1074/jbc.M206203200
*cite journal | author=Norman LP, Jiang W, Han X, "et al." |title=Targeted disruption of the meprin beta gene in mice leads to underrepresentation of knockout mice and changes in renal gene expression profiles. |journal=Mol. Cell. Biol. |volume=23 |issue= 4 |pages= 1221–30 |year= 2003 |pmid= 12556482 |doi=
*cite journal | author=Kimura K, Wakamatsu A, Suzuki Y, "et al." |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406

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  • Meprin A — Identifiers EC number 3.4.24.18 CAS number 148938 24 3 …   Wikipedia

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