UGT2B4

UGT2B4

UDP glucuronosyltransferase 2 family, polypeptide B4, also known as UGT2B4, is a human gene.cite web | title = Entrez Gene: UGT2B4 UDP glucuronosyltransferase 2 family, polypeptide B4| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7363| accessdate = ]

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References

Further reading

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*cite journal | author=Mackenzie PI, Owens IS, Burchell B, "et al." |title=The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence. |journal=Pharmacogenetics |volume=7 |issue= 4 |pages= 255–69 |year= 1997 |pmid= 9295054 |doi=
*cite journal | author=Kadlubar FF, Miller JA, Miller EC |title=Hepatic microsomal N-glucuronidation and nucleic acid binding of N-hydroxy arylamines in relation to urinary bladder carcinogenesis. |journal=Cancer Res. |volume=37 |issue= 3 |pages= 805–14 |year= 1977 |pmid= 13929 |doi=
*cite journal | author=Ritter JK, Chen F, Sheen YY, "et al." |title=Two human liver cDNAs encode UDP-glucuronosyltransferases with 2 log differences in activity toward parallel substrates including hyodeoxycholic acid and certain estrogen derivatives. |journal=Biochemistry |volume=31 |issue= 13 |pages= 3409–14 |year= 1992 |pmid= 1554722 |doi=
*cite journal | author=Fournel-Gigleux S, Jackson MR, Wooster R, Burchell B |title=Expression of a human liver cDNA encoding a UDP-glucuronosyltransferase catalysing the glucuronidation of hyodeoxycholic acid in cell culture. |journal=FEBS Lett. |volume=243 |issue= 2 |pages= 119–22 |year= 1989 |pmid= 2492950 |doi=
*cite journal | author=Jackson MR, McCarthy LR, Harding D, "et al." |title=Cloning of a human liver microsomal UDP-glucuronosyltransferase cDNA. |journal=Biochem. J. |volume=242 |issue= 2 |pages= 581–8 |year= 1987 |pmid= 3109396 |doi=
*cite journal | author=Monaghan G, Clarke DJ, Povey S, "et al." |title=Isolation of a human YAC contig encompassing a cluster of UGT2 genes and its regional localization to chromosome 4q13. |journal=Genomics |volume=23 |issue= 2 |pages= 496–9 |year= 1995 |pmid= 7835904 |doi= 10.1006/geno.1994.1531
*cite journal | author=Jin CJ, Miners JO, Lillywhite KJ, Mackenzie PI |title=cDNA cloning and expression of two new members of the human liver UDP-glucuronosyltransferase 2B subfamily. |journal=Biochem. Biophys. Res. Commun. |volume=194 |issue= 1 |pages= 496–503 |year= 1993 |pmid= 8333863 |doi= 10.1006/bbrc.1993.1847
*cite journal | author=Babu SR, Lakshmi VM, Huang GP, "et al." |title=Glucuronide conjugates of 4-aminobiphenyl and its N-hydroxy metabolites. pH stability and synthesis by human and dog liver. |journal=Biochem. Pharmacol. |volume=51 |issue= 12 |pages= 1679–85 |year= 1996 |pmid= 8687483 |doi=
*cite journal | author=Monaghan G, Burchell B, Boxer M |title=Structure of the human UGT2B4 gene encoding a bile acid UDP-glucuronosyltransferase. |journal=Mamm. Genome |volume=8 |issue= 9 |pages= 692–4 |year= 1997 |pmid= 9271674 |doi=
*cite journal | author=King CD, Rios GR, Assouline JA, Tephly TR |title=Expression of UDP-glucuronosyltransferases (UGTs) 2B7 and 1A6 in the human brain and identification of 5-hydroxytryptamine as a substrate. |journal=Arch. Biochem. Biophys. |volume=365 |issue= 1 |pages= 156–62 |year= 1999 |pmid= 10222050 |doi= 10.1006/abbi.1999.1155
*cite journal | author=Lévesque E, Beaulieu M, Hum DW, Bélanger A |title=Characterization and substrate specificity of UGT2B4 (E458): a UDP-glucuronosyltransferase encoded by a polymorphic gene. |journal=Pharmacogenetics |volume=9 |issue= 2 |pages= 207–16 |year= 1999 |pmid= 10376768 |doi=
*cite journal | author=Strassburg CP, Kneip S, Topp J, "et al." |title=Polymorphic gene regulation and interindividual variation of UDP-glucuronosyltransferase activity in human small intestine. |journal=J. Biol. Chem. |volume=275 |issue= 46 |pages= 36164–71 |year= 2000 |pmid= 10748067 |doi= 10.1074/jbc.M002180200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Barbier O, Torra IP, Sirvent A, "et al." |title=FXR induces the UGT2B4 enzyme in hepatocytes: a potential mechanism of negative feedback control of FXR activity. |journal=Gastroenterology |volume=124 |issue= 7 |pages= 1926–40 |year= 2003 |pmid= 12806625 |doi=
*cite journal | author=Barbier O, Duran-Sandoval D, Pineda-Torra I, "et al." |title=Peroxisome proliferator-activated receptor alpha induces hepatic expression of the human bile acid glucuronidating UDP-glucuronosyltransferase 2B4 enzyme. |journal=J. Biol. Chem. |volume=278 |issue= 35 |pages= 32852–60 |year= 2003 |pmid= 12810707 |doi= 10.1074/jbc.M305361200
*cite journal | author=Saeki M, Saito Y, Jinno H, "et al." |title=Single nucleotide polymorphisms and haplotype frequencies of UGT2B4 and UGT2B7 in a Japanese population. |journal=Drug Metab. Dispos. |volume=32 |issue= 9 |pages= 1048–54 |year= 2005 |pmid= 15319348 |doi=
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Kimura K, Wakamatsu A, Suzuki Y, "et al." |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406
*cite journal | author=Barre L, Fournel-Gigleux S, Finel M, "et al." |title=Substrate specificity of the human UDP-glucuronosyltransferase UGT2B4 and UGT2B7. Identification of a critical aromatic amino acid residue at position 33. |journal=FEBS J. |volume=274 |issue= 5 |pages= 1256–64 |year= 2007 |pmid= 17263731 |doi= 10.1111/j.1742-4658.2007.05670.x

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