CCNG1

Cyclin G1, also known as CCNG1, is a human gene.cite web | title = Entrez Gene: CCNG1 cyclin G1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=900| accessdate = ]

PBB_Summary
section_title =
summary_text = The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. The protein encoded by this gene is a member of the cyclin family and contains the cyclin box. The encoded protein lacks the protein destabilizing (PEST) sequence that is present in other family members. Transcriptional activation of this gene can be induced by tumor protein p53. Two transcript variants encoding the same protein have been identified for this gene.cite web | title = Entrez Gene: CCNG1 cyclin G1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=900| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Horne MC, Goolsby GL, Donaldson KL, "et al." |title=Cyclin G1 and cyclin G2 comprise a new family of cyclins with contrasting tissue-specific and cell cycle-regulated expression. |journal=J. Biol. Chem. |volume=271 |issue= 11 |pages= 6050–61 |year= 1996 |pmid= 8626390 |doi=
*cite journal | author=Bates S, Rowan S, Vousden KH |title=Characterisation of human cyclin G1 and G2: DNA damage inducible genes. |journal=Oncogene |volume=13 |issue= 5 |pages= 1103–9 |year= 1996 |pmid= 8806701 |doi=
*cite journal | author=Okamoto K, Kamibayashi C, Serrano M, "et al." |title=p53-dependent association between cyclin G and the B' subunit of protein phosphatase 2A. |journal=Mol. Cell. Biol. |volume=16 |issue= 11 |pages= 6593–602 |year= 1996 |pmid= 8887688 |doi=
*cite journal | author=Endo Y, Fujita T, Tamura K, "et al." |title=Structure and chromosomal assignment of the human cyclin G gene. |journal=Genomics |volume=38 |issue= 1 |pages= 92–5 |year= 1997 |pmid= 8954786 |doi= 10.1006/geno.1996.0598
*cite journal | author=Kanaoka Y, Kimura SH, Okazaki I, "et al." |title=GAK: a cyclin G associated kinase contains a tensin/auxilin-like domain. |journal=FEBS Lett. |volume=402 |issue= 1 |pages= 73–80 |year= 1997 |pmid= 9013862 |doi=
*cite journal | author=Kato MV |title=The mechanisms of death of an erythroleukemic cell line by p53: involvement of the microtubule and mitochondria. |journal=Leuk. Lymphoma |volume=33 |issue= 1-2 |pages= 181–6 |year= 1999 |pmid= 10194136 |doi=
*cite journal | author=Reimer CL, Borras AM, Kurdistani SK, "et al." |title=Altered regulation of cyclin G in human breast cancer and its specific localization at replication foci in response to DNA damage in p53+/+ cells. |journal=J. Biol. Chem. |volume=274 |issue= 16 |pages= 11022–9 |year= 1999 |pmid= 10196184 |doi=
*cite journal | author=Bennin DA, Don AS, Brake T, "et al." |title=Cyclin G2 associates with protein phosphatase 2A catalytic and regulatory B' subunits in active complexes and induces nuclear aberrations and a G1/S phase cell cycle arrest. |journal=J. Biol. Chem. |volume=277 |issue= 30 |pages= 27449–67 |year= 2002 |pmid= 11956189 |doi= 10.1074/jbc.M111693200
*cite journal | author=Jordan-Sciutto KL, Morgan K, Bowser R |title=Increased Cyclin G1 Immunoreactivity During Alzheimer's Disease. |journal= |volume=1 |issue= 6 |pages= 409–417 |year= |pmid= 12214116 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Zhao L, Samuels T, Winckler S, "et al." |title=Cyclin G1 has growth inhibitory activity linked to the ARF-Mdm2-p53 and pRb tumor suppressor pathways. |journal=Mol. Cancer Res. |volume=1 |issue= 3 |pages= 195–206 |year= 2003 |pmid= 12556559 |doi=
*cite journal | author=Baek WK, Kim D, Jung N, "et al." |title=Increased expression of cyclin G1 in leiomyoma compared with normal myometrium. |journal=Am. J. Obstet. Gynecol. |volume=188 |issue= 3 |pages= 634–9 |year= 2003 |pmid= 12634633 |doi=
*cite journal | author=Li JQ, Kubo A, Wu F, "et al." |title=Cyclin B1, unlike cyclin G1, increases significantly during colorectal carcinogenesis and during later metastasis to lymph nodes. |journal=Int. J. Oncol. |volume=22 |issue= 5 |pages= 1101–10 |year= 2003 |pmid= 12684677 |doi=
*cite journal | author=Ohtsuka T, Jensen MR, Kim HG, "et al." |title=The negative role of cyclin G in ATM-dependent p53 activation. |journal=Oncogene |volume=23 |issue= 31 |pages= 5405–8 |year= 2004 |pmid= 15077171 |doi= 10.1038/sj.onc.1207693
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Seo HR, Lee DH, Lee HJ, "et al." |title=Cyclin G1 overcomes radiation-induced G2 arrest and increases cell death through transcriptional activation of cyclin B1. |journal=Cell Death Differ. |volume=13 |issue= 9 |pages= 1475–84 |year= 2006 |pmid= 16322753 |doi= 10.1038/sj.cdd.4401822
*cite journal | author=Gramantieri L, Ferracin M, Fornari F, "et al." |title=Cyclin G1 is a target of miR-122a, a microRNA frequently down-regulated in human hepatocellular carcinoma. |journal=Cancer Res. |volume=67 |issue= 13 |pages= 6092–9 |year= 2007 |pmid= 17616664 |doi= 10.1158/0008-5472.CAN-06-4607

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