Vesicle-associated membrane protein 8

Vesicle-associated membrane protein 8

Vesicle-associated membrane protein 8 (endobrevin), also known as VAMP8, is a human gene.cite web | title = Entrez Gene: VAMP8 vesicle-associated membrane protein 8 (endobrevin)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8673| accessdate = ]

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summary_text = Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. It is associated with the perinuclear vesicular structures of the early endocytic compartment. It has been found that VAMP8 interacts specifically with the soluble NSF-attachment protein (alpha-SNAP), most likely through an VAMP8-containing SNARE complex.cite web | title = Entrez Gene: VAMP8 vesicle-associated membrane protein 8 (endobrevin)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8673| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Bonaldo MF, Lennon G, Soares MB |title=Normalization and subtraction: two approaches to facilitate gene discovery. |journal=Genome Res. |volume=6 |issue= 9 |pages= 791–806 |year= 1997 |pmid= 8889548 |doi=
*cite journal | author=Wong SH, Zhang T, Xu Y, "et al." |title=Endobrevin, a novel synaptobrevin/VAMP-like protein preferentially associated with the early endosome. |journal=Mol. Biol. Cell |volume=9 |issue= 6 |pages= 1549–63 |year= 1998 |pmid= 9614193 |doi=
*cite journal | author=Bui TD, Wong SH, Lu L, Hong W |title=Endobrevin maps to chromosome 2 in human and chromosome 6 in mouse. |journal=Genomics |volume=54 |issue= 3 |pages= 579–80 |year= 1999 |pmid= 9878266 |doi= 10.1006/geno.1998.5596
*cite journal | author=Fasshauer D, Antonin W, Margittai M, "et al." |title=Mixed and non-cognate SNARE complexes. Characterization of assembly and biophysical properties. |journal=J. Biol. Chem. |volume=274 |issue= 22 |pages= 15440–6 |year= 1999 |pmid= 10336434 |doi=
*cite journal | author=Kim PK, Hollerbach C, Trimble WS, "et al." |title=Identification of the endoplasmic reticulum targeting signal in vesicle-associated membrane proteins. |journal=J. Biol. Chem. |volume=274 |issue= 52 |pages= 36876–82 |year= 2000 |pmid= 10601239 |doi=
*cite journal | author=Paumet F, Le Mao J, Martin S, "et al." |title=Soluble NSF attachment protein receptors (SNAREs) in RBL-2H3 mast cells: functional role of syntaxin 4 in exocytosis and identification of a vesicle-associated membrane protein 8-containing secretory compartment. |journal=J. Immunol. |volume=164 |issue= 11 |pages= 5850–7 |year= 2000 |pmid= 10820264 |doi=
*cite journal | author=Antonin W, Holroyd C, Tikkanen R, "et al." |title=The R-SNARE endobrevin/VAMP-8 mediates homotypic fusion of early endosomes and late endosomes. |journal=Mol. Biol. Cell |volume=11 |issue= 10 |pages= 3289–98 |year= 2000 |pmid= 11029036 |doi=
*cite journal | author=Antonin W, Holroyd C, Fasshauer D, "et al." |title=A SNARE complex mediating fusion of late endosomes defines conserved properties of SNARE structure and function. |journal=EMBO J. |volume=19 |issue= 23 |pages= 6453–64 |year= 2001 |pmid= 11101518 |doi= 10.1093/emboj/19.23.6453
*cite journal | author=Nagamatsu S, Nakamichi Y, Watanabe T, "et al." |title=Localization of cellubrevin-related peptide, endobrevin, in the early endosome in pancreatic beta cells and its physiological function in exo-endocytosis of secretory granules. |journal=J. Cell. Sci. |volume=114 |issue= Pt 1 |pages= 219–227 |year= 2001 |pmid= 11112705 |doi=
*cite journal | author=Wade N, Bryant NJ, Connolly LM, "et al." |title=Syntaxin 7 complexes with mouse Vps10p tail interactor 1b, syntaxin 6, vesicle-associated membrane protein (VAMP)8, and VAMP7 in b16 melanoma cells. |journal=J. Biol. Chem. |volume=276 |issue= 23 |pages= 19820–7 |year= 2001 |pmid= 11278762 |doi= 10.1074/jbc.M010838200
*cite journal | author=Antonin W, Fasshauer D, Becker S, "et al." |title=Crystal structure of the endosomal SNARE complex reveals common structural principles of all SNAREs. |journal=Nat. Struct. Biol. |volume=9 |issue= 2 |pages= 107–11 |year= 2002 |pmid= 11786915 |doi= 10.1038/nsb746
*cite journal | author=Polgár J, Chung SH, Reed GL |title=Vesicle-associated membrane protein 3 (VAMP-3) and VAMP-8 are present in human platelets and are required for granule secretion. |journal=Blood |volume=100 |issue= 3 |pages= 1081–3 |year= 2002 |pmid= 12130530 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Imai A, Nashida T, Yoshie S, Shimomura H |title=Intracellular localisation of SNARE proteins in rat parotid acinar cells: SNARE complexes on the apical plasma membrane. |journal=Arch. Oral Biol. |volume=48 |issue= 8 |pages= 597–604 |year= 2003 |pmid= 12828989 |doi=
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Hillier LW, Graves TA, Fulton RS, "et al." |title=Generation and annotation of the DNA sequences of human chromosomes 2 and 4. |journal=Nature |volume=434 |issue= 7034 |pages= 724–31 |year= 2005 |pmid= 15815621 |doi= 10.1038/nature03466
*cite journal | author=Brinkman JF, Ottenheim CP, de Jong LA, "et al." |title=VAMP5 and VAMP8 are most likely not involved in primary open-angle glaucoma. |journal=Mol. Vis. |volume=11 |issue= |pages= 582–6 |year= 2006 |pmid= 16110299 |doi=
*cite journal | author=Oishi Y, Arakawa T, Tanimura A, "et al." |title=Role of VAMP-2, VAMP-7, and VAMP-8 in constitutive exocytosis from HSY cells. |journal=Histochem. Cell Biol. |volume=125 |issue= 3 |pages= 273–81 |year= 2007 |pmid= 16195891 |doi= 10.1007/s00418-005-0068-y
*cite journal | author=Shiffman D, Rowland CM, Louie JZ, "et al." |title=Gene variants of VAMP8 and HNRPUL1 are associated with early-onset myocardial infarction. |journal=Arterioscler. Thromb. Vasc. Biol. |volume=26 |issue= 7 |pages= 1613–8 |year= 2006 |pmid= 16690874 |doi= 10.1161/01.ATV.0000226543.77214.e4

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