PRPF4

PRP4 pre-mRNA processing factor 4 homolog (yeast), also known as PRPF4, is a human gene.cite web | title = Entrez Gene: PRPF4 PRP4 pre-mRNA processing factor 4 homolog (yeast)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9128| accessdate = ]

PBB_Summary
section_title =
summary_text = The removal of introns from nuclear pre-mRNAs occurs on complexes called spliceosomes, which are made up of 4 small nuclear ribonucleoprotein (snRNP) particles and an undefined number of transiently associated splicing factors. PRPF4 is 1 of several proteins that associate with U4 and U6 snRNPs. [supplied by OMIM] cite web | title = Entrez Gene: PRPF4 PRP4 pre-mRNA processing factor 4 homolog (yeast)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9128| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Horowitz DS, Krainer AR |title=A human protein required for the second step of pre-mRNA splicing is functionally related to a yeast splicing factor. |journal=Genes Dev. |volume=11 |issue= 1 |pages= 139–51 |year= 1997 |pmid= 9000057 |doi=
*cite journal | author=Lauber J, Plessel G, Prehn S, "et al." |title=The human U4/U6 snRNP contains 60 and 90kD proteins that are structurally homologous to the yeast splicing factors Prp4p and Prp3p. |journal=RNA |volume=3 |issue= 8 |pages= 926–41 |year= 1997 |pmid= 9257651 |doi=
*cite journal | author=Wang A, Forman-Kay J, Luo Y, "et al." |title=Identification and characterization of human genes encoding Hprp3p and Hprp4p, interacting components of the spliceosome. |journal=Hum. Mol. Genet. |volume=6 |issue= 12 |pages= 2117–26 |year= 1997 |pmid= 9328476 |doi=
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Horowitz DS, Kobayashi R, Krainer AR |title=A new cyclophilin and the human homologues of yeast Prp3 and Prp4 form a complex associated with U4/U6 snRNPs. |journal=RNA |volume=3 |issue= 12 |pages= 1374–87 |year= 1997 |pmid= 9404889 |doi=
*cite journal | author=Heng HH, Wang A, Hu J |title=Mapping of the human HPRP3 and HPRP4 genes encoding U4/U6-associated splicing factors to chromosomes 1q21.1 and 9q31-q33. |journal=Genomics |volume=48 |issue= 2 |pages= 273–5 |year= 1998 |pmid= 9521884 |doi= 10.1006/geno.1997.5181
*cite journal | author=Kojima T, Zama T, Wada K, "et al." |title=Cloning of human PRP4 reveals interaction with Clk1. |journal=J. Biol. Chem. |volume=276 |issue= 34 |pages= 32247–56 |year= 2001 |pmid= 11418604 |doi= 10.1074/jbc.M103790200
*cite journal | author=Gonzalez-Santos JM, Wang A, Jones J, "et al." |title=Central region of the human splicing factor Hprp3p interacts with Hprp4p. |journal=J. Biol. Chem. |volume=277 |issue= 26 |pages= 23764–72 |year= 2002 |pmid= 11971898 |doi= 10.1074/jbc.M111461200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Reidt U, Wahl MC, Fasshauer D, "et al." |title=Crystal structure of a complex between human spliceosomal cyclophilin H and a U4/U6 snRNP-60K peptide. |journal=J. Mol. Biol. |volume=331 |issue= 1 |pages= 45–56 |year= 2003 |pmid= 12875835 |doi=
*cite journal | author=Ingelfinger D, Göthel SF, Marahiel MA, "et al." |title=Two protein-protein interaction sites on the spliceosome-associated human cyclophilin CypH. |journal=Nucleic Acids Res. |volume=31 |issue= 16 |pages= 4791–6 |year= 2004 |pmid= 12907720 |doi=
*cite journal | author=Stanĕk D, Neugebauer KM |title=Detection of snRNP assembly intermediates in Cajal bodies by fluorescence resonance energy transfer. |journal=J. Cell Biol. |volume=166 |issue= 7 |pages= 1015–25 |year= 2004 |pmid= 15452143 |doi= 10.1083/jcb.200405160
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Andersen JS, Lam YW, Leung AK, "et al." |title=Nucleolar proteome dynamics. |journal=Nature |volume=433 |issue= 7021 |pages= 77–83 |year= 2005 |pmid= 15635413 |doi= 10.1038/nature03207
*cite journal | author=Barrios-Rodiles M, Brown KR, Ozdamar B, "et al." |title=High-throughput mapping of a dynamic signaling network in mammalian cells. |journal=Science |volume=307 |issue= 5715 |pages= 1621–5 |year= 2005 |pmid= 15761153 |doi= 10.1126/science.1105776
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Liu S, Rauhut R, Vornlocher HP, Lührmann R |title=The network of protein-protein interactions within the human U4/U6.U5 tri-snRNP. |journal=RNA |volume=12 |issue= 7 |pages= 1418–30 |year= 2006 |pmid= 16723661 |doi= 10.1261/rna.55406
*cite journal | author=Huang B, Ahn YT, McPherson L, "et al." |title=Interaction of PRP4 with Kruppel-like factor 13 regulates CCL5 transcription. |journal=J. Immunol. |volume=178 |issue= 11 |pages= 7081–7 |year= 2007 |pmid= 17513757 |doi=

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