CABIN1

Calcineurin binding protein 1, also known as CABIN1, is a human gene.cite web | title = Entrez Gene: CABIN1 calcineurin binding protein 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23523| accessdate = ]

PBB_Summary
section_title =
summary_text = Calcineurin plays an important role in the T-cell receptor-mediated signal transduction pathway. The protein encoded by this gene binds specifically to the activated form of calcineurin and inhibits calcineurin-mediated signal transduction. The encoded protein is found in the nucleus and contains a leucine zipper domain as well as several PEST motifs, sequences which confer targeted degradation to those proteins which contain them. At least four alternatively spliced transcripts have been found for this gene, but the full-length nature of most of them has not been determined.cite web | title = Entrez Gene: CABIN1 calcineurin binding protein 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23523| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Liu JO |title=Endogenous protein inhibitors of calcineurin. |journal=Biochem. Biophys. Res. Commun. |volume=311 |issue= 4 |pages= 1103–9 |year= 2004 |pmid= 14623296 |doi=
*cite journal | author=Laherty CD, Yang WM, Sun JM, "et al." |title=Histone deacetylases associated with the mSin3 corepressor mediate mad transcriptional repression. |journal=Cell |volume=89 |issue= 3 |pages= 349–56 |year= 1997 |pmid= 9150134 |doi=
*cite journal | author=Nagase T, Ishikawa K, Nakajima D, "et al." |title=Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. |journal=DNA Res. |volume=4 |issue= 2 |pages= 141–50 |year= 1997 |pmid= 9205841 |doi=
*cite journal | author=Sun L, Youn HD, Loh C, "et al." |title=Cabin 1, a negative regulator for calcineurin signaling in T lymphocytes. |journal=Immunity |volume=8 |issue= 6 |pages= 703–11 |year= 1998 |pmid= 9655484 |doi=
*cite journal | author=Youn HD, Sun L, Prywes R, Liu JO |title=Apoptosis of T cells mediated by Ca2+-induced release of the transcription factor MEF2. |journal=Science |volume=286 |issue= 5440 |pages= 790–3 |year= 1999 |pmid= 10531067 |doi=
*cite journal | author=Dunham I, Shimizu N, Roe BA, "et al." |title=The DNA sequence of human chromosome 22. |journal=Nature |volume=402 |issue= 6761 |pages= 489–95 |year= 1999 |pmid= 10591208 |doi= 10.1038/990031
*cite journal | author=Youn HD, Grozinger CM, Liu JO |title=Calcium regulates transcriptional repression of myocyte enhancer factor 2 by histone deacetylase 4. |journal=J. Biol. Chem. |volume=275 |issue= 29 |pages= 22563–7 |year= 2000 |pmid= 10825153 |doi= 10.1074/jbc.C000304200
*cite journal | author=Lai MM, Luo HR, Burnett PE, "et al." |title=The calcineurin-binding protein cain is a negative regulator of synaptic vesicle endocytosis. |journal=J. Biol. Chem. |volume=275 |issue= 44 |pages= 34017–20 |year= 2000 |pmid= 10931822 |doi= 10.1074/jbc.C000429200
*cite journal | author=Youn HD, Liu JO |title=Cabin1 represses MEF2-dependent Nur77 expression and T cell apoptosis by controlling association of histone deacetylases and acetylases with MEF2. |journal=Immunity |volume=13 |issue= 1 |pages= 85–94 |year= 2000 |pmid= 10933397 |doi=
*cite journal | author=Esau C, Boes M, Youn HD, "et al." |title=Deletion of calcineurin and myocyte enhancer factor 2 (MEF2) binding domain of Cabin1 results in enhanced cytokine gene expression in T cells. |journal=J. Exp. Med. |volume=194 |issue= 10 |pages= 1449–59 |year= 2001 |pmid= 11714752 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Han A, Pan F, Stroud JC, "et al." |title=Sequence-specific recruitment of transcriptional co-repressor Cabin1 by myocyte enhancer factor-2. |journal=Nature |volume=422 |issue= 6933 |pages= 730–4 |year= 2003 |pmid= 12700764 |doi= 10.1038/nature01555
*cite journal | author=Tagami H, Ray-Gallet D, Almouzni G, Nakatani Y |title=Histone H3.1 and H3.3 complexes mediate nucleosome assembly pathways dependent or independent of DNA synthesis. |journal=Cell |volume=116 |issue= 1 |pages= 51–61 |year= 2004 |pmid= 14718166 |doi=
*cite journal | author=Rodríguez A, Martínez-Martínez S, López-Maderuelo MD, "et al." |title=The linker region joining the catalytic and the regulatory domains of CnA is essential for binding to NFAT. |journal=J. Biol. Chem. |volume=280 |issue= 11 |pages= 9980–4 |year= 2005 |pmid= 15671033 |doi= 10.1074/jbc.C400401200
*cite journal | author=Li XN, Li YL, Liu GB, Ding YQ |title=Selection of choriocarcinoma-associated genes using bioinformatics. |journal=Di Yi Jun Yi Da Xue Xue Bao |volume=25 |issue= 1 |pages= 1–6 |year= 2007 |pmid= 15683985 |doi=
*cite journal | author=Pan F, Means AR, Liu JO |title=Calmodulin-dependent protein kinase IV regulates nuclear export of Cabin1 during T-cell activation. |journal=EMBO J. |volume=24 |issue= 12 |pages= 2104–13 |year= 2005 |pmid= 15902271 |doi= 10.1038/sj.emboj.7600685
*cite journal | author=Jang H, Cho EJ, Youn HD |title=A new calcineurin inhibition domain in Cabin1. |journal=Biochem. Biophys. Res. Commun. |volume=359 |issue= 1 |pages= 129–35 |year= 2007 |pmid= 17531200 |doi= 10.1016/j.bbrc.2007.05.066

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