KLF11

KLF11

Kruppel-like factor 11, also known as KLF11, is a human gene.cite web | title = Entrez Gene: KLF11 Kruppel-like factor 11| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8462| accessdate = ]

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ee also

* Kruppel-like factors
* Maturity onset diabetes of the young

References

Further reading

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*cite journal | author=Cook T, Gebelein B, Mesa K, "et al." |title=Molecular cloning and characterization of TIEG2 reveals a new subfamily of transforming growth factor-beta-inducible Sp1-like zinc finger-encoding genes involved in the regulation of cell growth. |journal=J. Biol. Chem. |volume=273 |issue= 40 |pages= 25929–36 |year= 1998 |pmid= 9748269 |doi=
*cite journal | author=Asano H, Li XS, Stamatoyannopoulos G |title=FKLF, a novel Krüppel-like factor that activates human embryonic and fetal beta-like globin genes. |journal=Mol. Cell. Biol. |volume=19 |issue= 5 |pages= 3571–9 |year= 1999 |pmid= 10207080 |doi=
*cite journal | author=Scohy S, Gabant P, Van Reeth T, "et al." |title=Identification of KLF13 and KLF14 (SP6), novel members of the SP/XKLF transcription factor family. |journal=Genomics |volume=70 |issue= 1 |pages= 93–101 |year= 2001 |pmid= 11087666 |doi= 10.1006/geno.2000.6362
*cite journal | author=Zhang JS, Moncrieffe MC, Kaczynski J, "et al." |title=A conserved alpha-helical motif mediates the interaction of Sp1-like transcriptional repressors with the corepressor mSin3A. |journal=Mol. Cell. Biol. |volume=21 |issue= 15 |pages= 5041–9 |year= 2001 |pmid= 11438660 |doi= 10.1128/MCB.21.15.5041-5049.2001
*cite journal | author=Jia L, Young MF, Powell J, "et al." |title=Gene expression profile of human bone marrow stromal cells: high-throughput expressed sequence tag sequencing analysis. |journal=Genomics |volume=79 |issue= 1 |pages= 7–17 |year= 2002 |pmid= 11827452 |doi= 10.1006/geno.2001.6683
*cite journal | author=Ellenrieder V, Zhang JS, Kaczynski J, Urrutia R |title=Signaling disrupts mSin3A binding to the Mad1-like Sin3-interacting domain of TIEG2, an Sp1-like repressor. |journal=EMBO J. |volume=21 |issue= 10 |pages= 2451–60 |year= 2002 |pmid= 12006497 |doi= 10.1093/emboj/21.10.2451
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Ou XM, Chen K, Shih JC |title=Dual functions of transcription factors, transforming growth factor-beta-inducible early gene (TIEG)2 and Sp3, are mediated by CACCC element and Sp1 sites of human monoamine oxidase (MAO) B gene. |journal=J. Biol. Chem. |volume=279 |issue= 20 |pages= 21021–8 |year= 2004 |pmid= 15024015 |doi= 10.1074/jbc.M312638200
*cite journal | author=Ellenrieder V, Buck A, Harth A, "et al." |title=KLF11 mediates a critical mechanism in TGF-beta signaling that is inactivated by Erk-MAPK in pancreatic cancer cells. |journal=Gastroenterology |volume=127 |issue= 2 |pages= 607–20 |year= 2004 |pmid= 15300592 |doi=
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Cao S, Fernandez-Zapico ME, Jin D, "et al." |title=KLF11-mediated repression antagonizes Sp1/sterol-responsive element-binding protein-induced transcriptional activation of caveolin-1 in response to cholesterol signaling. |journal=J. Biol. Chem. |volume=280 |issue= 3 |pages= 1901–10 |year= 2005 |pmid= 15531587 |doi= 10.1074/jbc.M407941200
*cite journal | author=Neve B, Fernandez-Zapico ME, Ashkenazi-Katalan V, "et al." |title=Role of transcription factor KLF11 and its diabetes-associated gene variants in pancreatic beta cell function. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=102 |issue= 13 |pages= 4807–12 |year= 2005 |pmid= 15774581 |doi= 10.1073/pnas.0409177102
*cite journal | author=Lim J, Hao T, Shaw C, "et al." |title=A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. |journal=Cell |volume=125 |issue= 4 |pages= 801–14 |year= 2006 |pmid= 16713569 |doi= 10.1016/j.cell.2006.03.032
*cite journal | author=Buck A, Buchholz M, Wagner M, "et al." |title=The tumor suppressor KLF11 mediates a novel mechanism in transforming growth factor beta-induced growth inhibition that is inactivated in pancreatic cancer. |journal=Mol. Cancer Res. |volume=4 |issue= 11 |pages= 861–72 |year= 2007 |pmid= 17114344 |doi= 10.1158/1541-7786.MCR-06-0081
*cite journal | author=Florez JC, Saxena R, Winckler W, "et al." |title=The Krüppel-like factor 11 (KLF11) Q62R polymorphism is not associated with type 2 diabetes in 8,676 people. |journal=Diabetes |volume=55 |issue= 12 |pages= 3620–4 |year= 2007 |pmid= 17130512 |doi= 10.2337/db06-0867
*cite journal | author=Spittau B, Wang Z, Boinska D, Krieglstein K |title=Functional domains of the TGF-beta-inducible transcription factor Tieg3 and detection of two putative nuclear localization signals within the zinc finger DNA-binding domain. |journal=J. Cell. Biochem. |volume=101 |issue= 3 |pages= 712–22 |year= 2007 |pmid= 17252542 |doi= 10.1002/jcb.21228
*cite journal | author=Niu X, Perakakis N, Laubner K, "et al." |title=Human Krüppel-like factor 11 inhibits human proinsulin promoter activity in pancreatic beta cells. |journal=Diabetologia |volume=50 |issue= 7 |pages= 1433–41 |year= 2007 |pmid= 17479246 |doi= 10.1007/s00125-007-0667-3

External links

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  • Kruppel-like factors — The Krüppel like family of transcription factors (Klfs), so named for their homology to the Drosophila melanogaster Krüppel protein, have been extensively studied for their roles in cell proliferation, differentiation and survival, especially in… …   Wikipedia

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