TSPAN7

Tetraspanin 7, also known as TSPAN7, is a human gene.cite web | title = Entrez Gene: TSPAN7 tetraspanin 7| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7102| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and may have a role in the control of neurite outgrowth. It is known to complex with integrins. This gene is associated with X-linked mental retardation and neuropsychiatric diseases such as Huntington's chorea, fragile X syndrome and myotonic dystrophy.cite web | title = Entrez Gene: TSPAN7 tetraspanin 7| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7102| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Castellví-Bel S, Milà M |title=Genes responsible for nonspecific mental retardation. |journal=Mol. Genet. Metab. |volume=72 |issue= 2 |pages= 104–8 |year= 2001 |pmid= 11161835 |doi= 10.1006/mgme.2000.3128
*cite journal | author=Berditchevski F |title=Complexes of tetraspanins with integrins: more than meets the eye. |journal=J. Cell. Sci. |volume=114 |issue= Pt 23 |pages= 4143–51 |year= 2002 |pmid= 11739647 |doi=
*cite journal | author=Takagi S, Fujikawa K, Imai T, "et al." |title=Identification of a highly specific surface marker of T-cell acute lymphoblastic leukemia and neuroblastoma as a new member of the transmembrane 4 superfamily. |journal=Int. J. Cancer |volume=61 |issue= 5 |pages= 706–15 |year= 1995 |pmid= 7768645 |doi=
*cite journal | author=Virtaneva KI, Emi N, Marken JS, "et al." |title=Chromosomal localization of three human genes coding for A15, L6, and S5.7 (TAPA1): all members of the transmembrane 4 superfamily of proteins. |journal=Immunogenetics |volume=39 |issue= 5 |pages= 329–34 |year= 1994 |pmid= 8168850 |doi=
*cite journal | author=Li SH, McInnis MG, Margolis RL, "et al." |title=Novel triplet repeat containing genes in human brain: cloning, expression, and length polymorphisms. |journal=Genomics |volume=16 |issue= 3 |pages= 572–9 |year= 1993 |pmid= 8325628 |doi= 10.1006/geno.1993.1232
*cite journal | author=Emi N, Kitaori K, Seto M, "et al." |title=Isolation of a novel cDNA clone showing marked similarity to ME491/CD63 superfamily. |journal=Immunogenetics |volume=37 |issue= 3 |pages= 193–8 |year= 1993 |pmid= 8420826 |doi=
*cite journal | author=Serru V, Le Naour F, Billard M, "et al." |title=Selective tetraspan-integrin complexes (CD81/alpha4beta1, CD151/alpha3beta1, CD151/alpha6beta1) under conditions disrupting tetraspan interactions. |journal=Biochem. J. |volume=340 ( Pt 1) |issue= |pages= 103–11 |year= 1999 |pmid= 10229664 |doi=
*cite journal | author=Holinski-Feder E, Chahrockh-Zadeh S, Rittinger O, "et al." |title=Nonsyndromic X-linked mental retardation: mapping of MRX58 to the pericentromeric region. |journal=Am. J. Med. Genet. |volume=86 |issue= 2 |pages= 102–6 |year= 1999 |pmid= 10449641 |doi=
*cite journal | author=Hosokawa Y, Ueyama E, Morikawa Y, "et al." |title=Molecular cloning of a cDNA encoding mouse A15, a member of the transmembrane 4 superfamily, and its preferential expression in brain neurons. |journal=Neurosci. Res. |volume=35 |issue= 4 |pages= 281–90 |year= 2000 |pmid= 10617319 |doi=
*cite journal | author=Zemni R, Bienvenu T, Vinet MC, "et al." |title=A new gene involved in X-linked mental retardation identified by analysis of an X;2 balanced translocation. |journal=Nat. Genet. |volume=24 |issue= 2 |pages= 167–70 |year= 2000 |pmid= 10655063 |doi= 10.1038/72829
*cite journal | author=Domínguez-Jiménez C, Yáñez-Mó M, Carreira A, "et al." |title=Involvement of alpha3 integrin/tetraspanin complexes in the angiogenic response induced by angiotensin II. |journal=FASEB J. |volume=15 |issue= 8 |pages= 1457–9 |year= 2001 |pmid= 11387256 |doi=
*cite journal | author=Abidi FE, Holinski-Feder E, Rittinger O, "et al." |title=A novel 2 bp deletion in the TM4SF2 gene is associated with MRX58. |journal=J. Med. Genet. |volume=39 |issue= 6 |pages= 430–3 |year= 2002 |pmid= 12070254 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Kitano T, Schwarz C, Nickel B, Pääbo S |title=Gene diversity patterns at 10 X-chromosomal loci in humans and chimpanzees. |journal=Mol. Biol. Evol. |volume=20 |issue= 8 |pages= 1281–9 |year= 2004 |pmid= 12777533 |doi= 10.1093/molbev/msg134
*cite journal | author=Maranduba CM, Sá Moreira E, Müller Orabona G, "et al." |title=Does the P172H mutation at the TM4SF2 gene cause X-linked mental retardation? |journal=Am. J. Med. Genet. A |volume=124 |issue= 4 |pages= 413–5 |year= 2004 |pmid= 14735593 |doi= 10.1002/ajmg.a.20401
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Ewing RM, Chu P, Elisma F, "et al." |title=Large-scale mapping of human protein-protein interactions by mass spectrometry. |journal=Mol. Syst. Biol. |volume=3 |issue= |pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134

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