MAPKAP1

MAPKAP1

Mitogen-activated protein kinase associated protein 1, also known as MAPKAP1, is a human gene.cite web | title = Entrez Gene: MAPKAP1 mitogen-activated protein kinase associated protein 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=79109| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a protein that is highly similar to the yeast SIN1 protein, a stress-activated protein kinase. Alternatively spliced transcript variants encoding distinct isoforms have been described. Alternate polyadenylation sites as well as alternate 3' UTRs have been identified for transcripts of this gene.cite web | title = Entrez Gene: MAPKAP1 mitogen-activated protein kinase associated protein 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=79109| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Colicelli J, Nicolette C, Birchmeier C, "et al." |title=Expression of three mammalian cDNAs that interfere with RAS function in Saccharomyces cerevisiae. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=88 |issue= 7 |pages= 2913–7 |year= 1991 |pmid= 1849280 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Jin J, Smith FD, Stark C, "et al." |title=Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization. |journal=Curr. Biol. |volume=14 |issue= 16 |pages= 1436–50 |year= 2004 |pmid= 15324660 |doi= 10.1016/j.cub.2004.07.051
*cite journal | author=Schroder W, Cloonan N, Bushell G, Sculley T |title=Alternative polyadenylation and splicing of mRNAs transcribed from the human Sin1 gene. |journal=Gene |volume=339 |issue= |pages= 17–23 |year= 2004 |pmid= 15363842 |doi= 10.1016/j.gene.2004.07.001
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Schroder W, Bushell G, Sculley T |title=The human stress-activated protein kinase-interacting 1 gene encodes JNK-binding proteins. |journal=Cell. Signal. |volume=17 |issue= 6 |pages= 761–7 |year= 2005 |pmid= 15722200 |doi= 10.1016/j.cellsig.2004.10.015
*cite journal | author=Benzinger A, Muster N, Koch HB, "et al." |title=Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer. |journal=Mol. Cell Proteomics |volume=4 |issue= 6 |pages= 785–95 |year= 2005 |pmid= 15778465 |doi= 10.1074/mcp.M500021-MCP200
*cite journal | author=Cheng J, Zhang D, Kim K, "et al." |title=Mip1, an MEKK2-interacting protein, controls MEKK2 dimerization and activation. |journal=Mol. Cell. Biol. |volume=25 |issue= 14 |pages= 5955–64 |year= 2005 |pmid= 15988011 |doi= 10.1128/MCB.25.14.5955-5964.2005
*cite journal | author=Venables JP, Bourgeois CF, Dalgliesh C, "et al." |title=Up-regulation of the ubiquitous alternative splicing factor Tra2beta causes inclusion of a germ cell-specific exon. |journal=Hum. Mol. Genet. |volume=14 |issue= 16 |pages= 2289–303 |year= 2005 |pmid= 16000324 |doi= 10.1093/hmg/ddi233
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Frias MA, Thoreen CC, Jaffe JD, "et al." |title=mSin1 is necessary for Akt/PKB phosphorylation, and its isoforms define three distinct mTORC2s. |journal=Curr. Biol. |volume=16 |issue= 18 |pages= 1865–70 |year= 2006 |pmid= 16919458 |doi= 10.1016/j.cub.2006.08.001
*cite journal | author=Jacinto E, Facchinetti V, Liu D, "et al." |title=SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity. |journal=Cell |volume=127 |issue= 1 |pages= 125–37 |year= 2006 |pmid= 16962653 |doi= 10.1016/j.cell.2006.08.033
*cite journal | author=Yang Q, Inoki K, Ikenoue T, Guan KL |title=Identification of Sin1 as an essential TORC2 component required for complex formation and kinase activity. |journal=Genes Dev. |volume=20 |issue= 20 |pages= 2820–32 |year= 2006 |pmid= 17043309 |doi= 10.1101/gad.1461206
*cite journal | author=Makino C, Sano Y, Shinagawa T, "et al." |title=Sin1 binds to both ATF-2 and p38 and enhances ATF-2-dependent transcription in an SAPK signaling pathway. |journal=Genes Cells |volume=11 |issue= 11 |pages= 1239–51 |year= 2007 |pmid= 17054722 |doi= 10.1111/j.1365-2443.2006.01016.x
*cite journal | author=Olsen JV, Blagoev B, Gnad F, "et al." |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026
*cite journal | author=Schroder WA, Buck M, Cloonan N, "et al." |title=Human Sin1 contains Ras-binding and pleckstrin homology domains and suppresses Ras signalling. |journal=Cell. Signal. |volume=19 |issue= 6 |pages= 1279–89 |year= 2007 |pmid= 17303383 |doi= 10.1016/j.cellsig.2007.01.013

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