MYH1

MYH1

Myosin, heavy chain 1, skeletal muscle, adult, also known as MYH1, is a human gene.cite web | title = Entrez Gene: MYH1 myosin, heavy chain 1, skeletal muscle, adult| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4619| accessdate = ]

PBB_Summary
section_title =
summary_text = Myosin is a major contractile protein which converts chemical energy into mechanical energy through the hydrolysis of ATP. Myosin is a hexameric protein composed of a pair of myosin heavy chains (MYH) and two pairs of nonidentical light chains. Myosin heavy chains are encoded by a multigene family. In mammals at least 10 different myosin heavy chain (MYH) isoforms have been described from striated, smooth, and nonmuscle cells. These isoforms show expression that is spatially and temporally regulated during development.cite web | title = Entrez Gene: MYH1 myosin, heavy chain 1, skeletal muscle, adult| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4619| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Yoon SJ, Seiler SH, Kucherlapati R, Leinwand L |title=Organization of the human skeletal myosin heavy chain gene cluster. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=89 |issue= 24 |pages= 12078–82 |year= 1993 |pmid= 1465443 |doi=
*cite journal | author=Saez L, Leinwand LA |title=Characterization of diverse forms of myosin heavy chain expressed in adult human skeletal muscle. |journal=Nucleic Acids Res. |volume=14 |issue= 7 |pages= 2951–69 |year= 1986 |pmid= 2421254 |doi=
*cite journal | author=Leinwand LA, Saez L, McNally E, Nadal-Ginard B |title=Isolation and characterization of human myosin heavy chain genes. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=80 |issue= 12 |pages= 3716–20 |year= 1983 |pmid= 6304733 |doi=
*cite journal | author=Smerdu V, Karsch-Mizrachi I, Campione M, "et al." |title=Type IIx myosin heavy chain transcripts are expressed in type IIb fibers of human skeletal muscle. |journal=Am. J. Physiol. |volume=267 |issue= 6 Pt 1 |pages= C1723–8 |year= 1995 |pmid= 7545970 |doi=
*cite journal | author=Weiss A, McDonough D, Wertman B, "et al." |title=Organization of human and mouse skeletal myosin heavy chain gene clusters is highly conserved. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=96 |issue= 6 |pages= 2958–63 |year= 1999 |pmid= 10077619 |doi=
*cite journal | author=Weiss A, Schiaffino S, Leinwand LA |title=Comparative sequence analysis of the complete human sarcomeric myosin heavy chain family: implications for functional diversity. |journal=J. Mol. Biol. |volume=290 |issue= 1 |pages= 61–75 |year= 1999 |pmid= 10388558 |doi= 10.1006/jmbi.1999.2865
*cite journal | author=Daugaard JR, Nielsen JN, Kristiansen S, "et al." |title=Fiber type-specific expression of GLUT4 in human skeletal muscle: influence of exercise training. |journal=Diabetes |volume=49 |issue= 7 |pages= 1092–5 |year= 2000 |pmid= 10909963 |doi=
*cite journal | author=Korfage JA, Brugman P, Van Eijden TM |title=Intermuscular and intramuscular differences in myosin heavy chain composition of the human masticatory muscles. |journal=J. Neurol. Sci. |volume=178 |issue= 2 |pages= 95–106 |year= 2000 |pmid= 11018701 |doi=
*cite journal | author=Konig S, Burkman J, Fitzgerald J, "et al." |title=Modular organization of phylogenetically conserved domains controlling developmental regulation of the human skeletal myosin heavy chain gene family. |journal=J. Biol. Chem. |volume=277 |issue= 31 |pages= 27593–605 |year= 2002 |pmid= 11971910 |doi= 10.1074/jbc.M203162200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Villacé P, Marión RM, Ortín J |title=The composition of Staufen-containing RNA granules from human cells indicates their role in the regulated transport and translation of messenger RNAs. |journal=Nucleic Acids Res. |volume=32 |issue= 8 |pages= 2411–20 |year= 2004 |pmid= 15121898 |doi= 10.1093/nar/gkh552
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Kimura K, Wakamatsu A, Suzuki Y, "et al." |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406
*cite journal | author=Pontén EM, Stål PS |title=Decreased capillarization and a shift to fast myosin heavy chain IIx in the biceps brachii muscle from young adults with spastic paresis. |journal=J. Neurol. Sci. |volume=253 |issue= 1-2 |pages= 25–33 |year= 2007 |pmid= 17196619 |doi= 10.1016/j.jns.2006.11.006

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