- Interleukin 20 receptor, alpha subunit
Interleukin 20 receptor, alpha subunit is a subunit for the
interleukin-20 receptor . IL20RA is its humangene .cite web | title = Entrez Gene: IL20RA interleukin 20 receptor, alpha| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=53832| accessdate = ]PBB_Summary
section_title =
summary_text = The protein encoded by this gene is a receptor for interleukin 20 (IL20), a cytokine that may be involved in epidermal function. The receptor of IL20 is a heterodimeric receptor complex consisting of this protein and interleukin 20 receptor beta (IL20B). This gene and IL20B are highly expressed in skin. The expression of both genes is found to be upregulated in Psoriasis.cite web | title = Entrez Gene: IL20RA interleukin 20 receptor, alpha| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=53832| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Bonaldo MF, Lennon G, Soares MB |title=Normalization and subtraction: two approaches to facilitate gene discovery. |journal=Genome Res. |volume=6 |issue= 9 |pages= 791–806 |year= 1997 |pmid= 8889548 |doi=
*cite journal | author=Xie MH, Aggarwal S, Ho WH, "et al." |title=Interleukin (IL)-22, a novel human cytokine that signals through the interferon receptor-related proteins CRF2-4 and IL-22R. |journal=J. Biol. Chem. |volume=275 |issue= 40 |pages= 31335–9 |year= 2000 |pmid= 10875937 |doi= 10.1074/jbc.M005304200
*cite journal | author=Blumberg H, Conklin D, Xu WF, "et al." |title=Interleukin 20: discovery, receptor identification, and role in epidermal function. |journal=Cell |volume=104 |issue= 1 |pages= 9–19 |year= 2001 |pmid= 11163236 |doi=
*cite journal | author=Dumoutier L, Leemans C, Lejeune D, "et al." |title=Cutting edge: STAT activation by IL-19, IL-20 and mda-7 through IL-20 receptor complexes of two types. |journal=J. Immunol. |volume=167 |issue= 7 |pages= 3545–9 |year= 2001 |pmid= 11564763 |doi=
*cite journal | author=Wang M, Tan Z, Zhang R, "et al." |title=Interleukin 24 (MDA-7/MOB-5) signals through two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2. |journal=J. Biol. Chem. |volume=277 |issue= 9 |pages= 7341–7 |year= 2002 |pmid= 11706020 |doi= 10.1074/jbc.M106043200
*cite journal | author=Parrish-Novak J, Xu W, Brender T, "et al." |title=Interleukins 19, 20, and 24 signal through two distinct receptor complexes. Differences in receptor-ligand interactions mediate unique biological functions. |journal=J. Biol. Chem. |volume=277 |issue= 49 |pages= 47517–23 |year= 2003 |pmid= 12351624 |doi= 10.1074/jbc.M205114200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Clark HF, Gurney AL, Abaya E, "et al." |title=The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. |journal=Genome Res. |volume=13 |issue= 10 |pages= 2265–70 |year= 2003 |pmid= 12975309 |doi= 10.1101/gr.1293003
*cite journal | author=Mungall AJ, Palmer SA, Sims SK, "et al." |title=The DNA sequence and analysis of human chromosome 6. |journal=Nature |volume=425 |issue= 6960 |pages= 805–11 |year= 2003 |pmid= 14574404 |doi= 10.1038/nature02055
*cite journal | author=Pletnev S, Magracheva E, Kozlov S, "et al." |title=Characterization of the recombinant extracellular domains of human interleukin-20 receptors and their complexes with interleukin-19 and interleukin-20. |journal=Biochemistry |volume=42 |issue= 43 |pages= 12617–24 |year= 2003 |pmid= 14580208 |doi= 10.1021/bi0354583
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Sheikh F, Baurin VV, Lewis-Antes A, "et al." |title=Cutting edge: IL-26 signals through a novel receptor complex composed of IL-20 receptor 1 and IL-10 receptor 2. |journal=J. Immunol. |volume=172 |issue= 4 |pages= 2006–10 |year= 2004 |pmid= 14764663 |doi=
*cite journal | author=Hör S, Pirzer H, Dumoutier L, "et al." |title=The T-cell lymphokine interleukin-26 targets epithelial cells through the interleukin-20 receptor 1 and interleukin-10 receptor 2 chains. |journal=J. Biol. Chem. |volume=279 |issue= 32 |pages= 33343–51 |year= 2004 |pmid= 15178681 |doi= 10.1074/jbc.M405000200
*cite journal | author=Zhang Z, Henzel WJ |title=Signal peptide prediction based on analysis of experimentally verified cleavage sites. |journal=Protein Sci. |volume=13 |issue= 10 |pages= 2819–24 |year= 2005 |pmid= 15340161 |doi= 10.1110/ps.04682504PBB_Controls
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