JARID1C

JARID1C

Jumonji, AT rich interactive domain 1C, also known as JARID1C, is a human gene.cite web | title = Entrez Gene: JARID1C jumonji, AT rich interactive domain 1C| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8242| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene is a member of the SMCY homolog family and encodes a protein with one ARID domain, one JmjC domain, one JmjN domain and two PHD-type zinc fingers. The DNA-binding motifs suggest this protein is involved in the regulation of transcription and chromatin remodeling. Mutations in this gene have been associated with X-linked mental retardation. Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only one has been determined.cite web | title = Entrez Gene: JARID1C jumonji, AT rich interactive domain 1C| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8242| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Agulnik AI, Mitchell MJ, Mattei MG, "et al." |title=A novel X gene with a widely transcribed Y-linked homologue escapes X-inactivation in mouse and human. |journal=Hum. Mol. Genet. |volume=3 |issue= 6 |pages= 879–84 |year= 1994 |pmid= 7951230 |doi=
*cite journal | author=Wu J, Ellison J, Salido E, "et al." |title=Isolation and characterization of XE169, a novel human gene that escapes X-inactivation. |journal=Hum. Mol. Genet. |volume=3 |issue= 1 |pages= 153–60 |year= 1994 |pmid= 8162017 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Agate RJ, Choe M, Arnold AP |title=Sex differences in structure and expression of the sex chromosome genes CHD1Z and CHD1W in zebra finches. |journal=Mol. Biol. Evol. |volume=21 |issue= 2 |pages= 384–96 |year= 2004 |pmid= 14660691 |doi= 10.1093/molbev/msh027
*cite journal | author=Beausoleil SA, Jedrychowski M, Schwartz D, "et al." |title=Large-scale characterization of HeLa cell nuclear phosphoproteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130–5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101
*cite journal | author=Jensen LR, Amende M, Gurok U, "et al." |title=Mutations in the JARID1C gene, which is involved in transcriptional regulation and chromatin remodeling, cause X-linked mental retardation. |journal=Am. J. Hum. Genet. |volume=76 |issue= 2 |pages= 227–36 |year= 2005 |pmid= 15586325 |doi= 10.1086/427563
*cite journal | author=Ross MT, Grafham DV, Coffey AJ, "et al." |title=The DNA sequence of the human X chromosome. |journal=Nature |volume=434 |issue= 7031 |pages= 325–37 |year= 2005 |pmid= 15772651 |doi= 10.1038/nature03440
*cite journal | author=Kimura K, Wakamatsu A, Suzuki Y, "et al." |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406
*cite journal | author=Santos C, Rodriguez-Revenga L, Madrigal I, "et al." |title=A novel mutation in JARID1C gene associated with mental retardation. |journal=Eur. J. Hum. Genet. |volume=14 |issue= 5 |pages= 583–6 |year= 2006 |pmid= 16538222 |doi= 10.1038/sj.ejhg.5201608
*cite journal | author=Tzschach A, Lenzner S, Moser B, "et al." |title=Novel JARID1C/SMCX mutations in patients with X-linked mental retardation. |journal=Hum. Mutat. |volume=27 |issue= 4 |pages= 389 |year= 2006 |pmid= 16541399 |doi= 10.1002/humu.9420
*cite journal | author=Beausoleil SA, Villén J, Gerber SA, "et al." |title=A probability-based approach for high-throughput protein phosphorylation analysis and site localization. |journal=Nat. Biotechnol. |volume=24 |issue= 10 |pages= 1285–92 |year= 2006 |pmid= 16964243 |doi= 10.1038/nbt1240
*cite journal | author=Olsen JV, Blagoev B, Gnad F, "et al." |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026
*cite journal | author=Iwase S, Lan F, Bayliss P, "et al." |title=The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases. |journal=Cell |volume=128 |issue= 6 |pages= 1077–88 |year= 2007 |pmid= 17320160 |doi= 10.1016/j.cell.2007.02.017
*cite journal | author=Tahiliani M, Mei P, Fang R, "et al." |title=The histone H3K4 demethylase SMCX links REST target genes to X-linked mental retardation. |journal=Nature |volume=447 |issue= 7144 |pages= 601–5 |year= 2007 |pmid= 17468742 |doi= 10.1038/nature05823

External links

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PBB_Controls
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