TAF1C

TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa, also known as TAF1C, is a human gene.cite web | title = Entrez Gene: TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9013| accessdate = ]

PBB_Summary
section_title =
summary_text = Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes the largest SL1-specific TAF. Two transcripts encoding different isoforms have been identified.cite web | title = Entrez Gene: TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9013| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Comai L, Zomerdijk JC, Beckmann H, "et al." |title=Reconstitution of transcription factor SL1: exclusive binding of TBP by SL1 or TFIID subunits. |journal=Science |volume=266 |issue= 5193 |pages= 1966–72 |year= 1995 |pmid= 7801123 |doi=
*cite journal | author=Di Pietro C, Rapisarda A, Amico V, "et al." |title=Genomic localization of the human genes TAF1A, TAF1B and TAF1C, encoding TAF(I)48, TAF(I)63 and TAF(I)110 subunits of class I general transcription initiation factor SL1. |journal=Cytogenet. Cell Genet. |volume=89 |issue= 1-2 |pages= 133–6 |year= 2000 |pmid= 10894955 |doi=
*cite journal | author=Zhai W, Comai L |title=Repression of RNA polymerase I transcription by the tumor suppressor p53. |journal=Mol. Cell. Biol. |volume=20 |issue= 16 |pages= 5930–8 |year= 2000 |pmid= 10913176 |doi=
*cite journal | author=Miller G, Panov KI, Friedrich JK, "et al." |title=hRRN3 is essential in the SL1-mediated recruitment of RNA Polymerase I to rRNA gene promoters. |journal=EMBO J. |volume=20 |issue= 6 |pages= 1373–82 |year= 2001 |pmid= 11250903 |doi= 10.1093/emboj/20.6.1373
*cite journal | author=Yuan X, Zhao J, Zentgraf H, "et al." |title=Multiple interactions between RNA polymerase I, TIF-IA and TAF(I) subunits regulate preinitiation complex assembly at the ribosomal gene promoter. |journal=EMBO Rep. |volume=3 |issue= 11 |pages= 1082–7 |year= 2003 |pmid= 12393749 |doi= 10.1093/embo-reports/kvf212
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Yamamoto K, Yamamoto M, Hanada K, "et al." |title=Multiple protein-protein interactions by RNA polymerase I-associated factor PAF49 and role of PAF49 in rRNA transcription. |journal=Mol. Cell. Biol. |volume=24 |issue= 14 |pages= 6338–49 |year= 2004 |pmid= 15226435 |doi= 10.1128/MCB.24.14.6338-6349.2004
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Grandori C, Gomez-Roman N, Felton-Edkins ZA, "et al." |title=c-Myc binds to human ribosomal DNA and stimulates transcription of rRNA genes by RNA polymerase I. |journal=Nat. Cell Biol. |volume=7 |issue= 3 |pages= 311–8 |year= 2005 |pmid= 15723054 |doi= 10.1038/ncb1224
*cite journal | author=Friedrich JK, Panov KI, Cabart P, "et al." |title=TBP-TAF complex SL1 directs RNA polymerase I pre-initiation complex formation and stabilizes upstream binding factor at the rDNA promoter. |journal=J. Biol. Chem. |volume=280 |issue= 33 |pages= 29551–8 |year= 2005 |pmid= 15970593 |doi= 10.1074/jbc.M501595200
*cite journal | author=Zhang C, Comai L, Johnson DL |title=PTEN represses RNA Polymerase I transcription by disrupting the SL1 complex. |journal=Mol. Cell. Biol. |volume=25 |issue= 16 |pages= 6899–911 |year= 2005 |pmid= 16055704 |doi= 10.1128/MCB.25.16.6899-6911.2005
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Kimura K, Wakamatsu A, Suzuki Y, "et al." |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406

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