FOXN3

Checkpoint suppressor 1, also known as CHES1, is a human gene.cite web | title = Entrez Gene: CHES1 checkpoint suppressor 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1112| accessdate = ]

PBB_Summary
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summary_text = This gene is a member of the forkhead/winged helix transcription factor family. Checkpoints are eukaryotic DNA damage-inducible cell cycle arrests at G1 and G2. Checkpoint suppressor 1 suppresses multiple yeast checkpoint mutations including mec1, rad9, rad53 and dun1 by activating a MEC1-independent checkpoint pathway. Alternative splicing is observed at the locus, resulting in distinct isoforms.cite web | title = Entrez Gene: CHES1 checkpoint suppressor 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1112| accessdate = ]

ee also

* FOX proteins

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Field LL, Tobias R, Thomson G, Plon S |title=Susceptibility to insulin-dependent diabetes mellitus maps to a locus (IDDM11) on human chromosome 14q24.3-q31. |journal=Genomics |volume=33 |issue= 1 |pages= 1–8 |year= 1996 |pmid= 8617492 |doi= 10.1006/geno.1996.0153
*cite journal | author=Hillier LD, Lennon G, Becker M, "et al." |title=Generation and analysis of 280,000 human expressed sequence tags. |journal=Genome Res. |volume=6 |issue= 9 |pages= 807–28 |year= 1997 |pmid= 8889549 |doi=
*cite journal | author=Pati D, Keller C, Groudine M, Plon SE |title=Reconstitution of a MEC1-independent checkpoint in yeast by expression of a novel human fork head cDNA. |journal=Mol. Cell. Biol. |volume=17 |issue= 6 |pages= 3037–46 |year= 1997 |pmid= 9154802 |doi=
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Yu Y, Zhang C, Zhou G, "et al." |title=Gene expression profiling in human fetal liver and identification of tissue- and developmental-stage-specific genes through compiled expression profiles and efficient cloning of full-length cDNAs. |journal=Genome Res. |volume=11 |issue= 8 |pages= 1392–403 |year= 2001 |pmid= 11483580 |doi= 10.1101/gr.175501
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Heilig R, Eckenberg R, Petit JL, "et al." |title=The DNA sequence and analysis of human chromosome 14. |journal=Nature |volume=421 |issue= 6923 |pages= 601–7 |year= 2003 |pmid= 12508121 |doi= 10.1038/nature01348
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Lehner B, Sanderson CM |title=A protein interaction framework for human mRNA degradation. |journal=Genome Res. |volume=14 |issue= 7 |pages= 1315–23 |year= 2004 |pmid= 15231747 |doi= 10.1101/gr.2122004
*cite journal | author=Suzuki Y, Yamashita R, Shirota M, "et al." |title=Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. |journal=Genome Res. |volume=14 |issue= 9 |pages= 1711–8 |year= 2004 |pmid= 15342556 |doi= 10.1101/gr.2435604
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Scott KL, Plon SE |title=CHES1/FOXN3 interacts with Ski-interacting protein and acts as a transcriptional repressor. |journal=Gene |volume=359 |issue= |pages= 119–26 |year= 2005 |pmid= 16102918 |doi= 10.1016/j.gene.2005.06.014
*cite journal | author=Busygina V, Kottemann MC, Scott KL, "et al." |title=Multiple endocrine neoplasia type 1 interacts with forkhead transcription factor CHES1 in DNA damage response. |journal=Cancer Res. |volume=66 |issue= 17 |pages= 8397–403 |year= 2007 |pmid= 16951149 |doi= 10.1158/0008-5472.CAN-06-0061
*cite journal | author=Katoh H, Ojima H, Kokubu A, "et al." |title=Genetically distinct and clinically relevant classification of hepatocellular carcinoma: putative therapeutic targets. |journal=Gastroenterology |volume=133 |issue= 5 |pages= 1475–86 |year= 2007 |pmid= 17983802 |doi= 10.1053/j.gastro.2007.08.038

External links

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