NUP160

Nucleoporin 160kDa
Identifiers
Symbols	NUP160; DKFZp686M14102; MGC150678; MGC150679
External IDs	OMIM: 607614 MGI: 1926227 HomoloGene: 32509 GeneCards: NUP160 Gene
Gene Ontology Molecular function • nucleocytoplasmic transporter activity • protein binding Cellular component • kinetochore • nucleus • nuclear envelope • nuclear envelope • nuclear pore • cytosol • Nup107-160 complex • Nup107-160 complex Biological process • M phase of mitotic cell cycle • mitotic prometaphase • mitotic cell cycle • carbohydrate metabolic process • mRNA export from nucleus • hexose transport • regulation of glucose transport • protein transport • glucose transport • viral reproduction • transmembrane transport Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	23279	59015
Ensembl	ENSG00000030066	ENSMUSG00000051329
UniProt	Q12769	Q9Z0W3
RefSeq (mRNA)	NM_015231	NM_021512.2
RefSeq (protein)	NP_056046	NP_067487.1
Location (UCSC)	Chr 11: 47.8 – 47.87 Mb	Chr 2: 90.52 – 90.58 Mb
PubMed search	[1]	[2]

Nuclear pore complex protein Nup160 is a protein that in humans is encoded by the NUP160 gene.^[1][2]

NUP160 is 1 of up to 60 proteins that make up the 120-MD nuclear pore complex, which mediates nucleoplasmic transport.[supplied by OMIM]^[2]

References

1. ^ Vasu S, Shah S, Orjalo A, Park M, Fischer WH, Forbes DJ (Oct 2001). "Novel vertebrate nucleoporins Nup133 and Nup160 play a role in mRNA export". J Cell Biol 155 (3): 339–54. doi:10.1083/jcb.200108007. PMC 2150853. PMID 11684705. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2150853. 
2. ^ ^{a b} "Entrez Gene: NUP160 nucleoporin 160kDa". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23279. 

Further reading

• Nagase T, Seki N, Ishikawa K, et al. (1996). "Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1.". DNA Res. 3 (1): 17–24. doi:10.1093/dnares/3.1.17. PMID 8724849. 
• Belgareh N, Rabut G, Baï SW, et al. (2001). "An evolutionarily conserved NPC subcomplex, which redistributes in part to kinetochores in mammalian cells.". J. Cell Biol. 154 (6): 1147–60. doi:10.1083/jcb.200101081. PMC 2150808. PMID 11564755. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2150808. 
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241. 
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
• Loïodice I, Alves A, Rabut G, et al. (2005). "The entire Nup107-160 complex, including three new members, is targeted as one entity to kinetochores in mitosis.". Mol. Biol. Cell 15 (7): 3333–44. doi:10.1091/mbc.E03-12-0878. PMC 452587. PMID 15146057. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=452587. 
• Lehner B, Sanderson CM (2004). "A protein interaction framework for human mRNA degradation.". Genome Res. 14 (7): 1315–23. doi:10.1101/gr.2122004. PMC 442147. PMID 15231747. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=442147. 
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=528928. 
• Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle.". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. doi:10.1073/pnas.0507066103. PMC 1459365. PMID 16565220. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1459365. 
• Orjalo AV, Arnaoutov A, Shen Z, et al. (2006). "The Nup107-160 nucleoporin complex is required for correct bipolar spindle assembly.". Mol. Biol. Cell 17 (9): 3806–18. doi:10.1091/mbc.E05-11-1061. PMC 1593160. PMID 16807356. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1593160. 
• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. 
• Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry.". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1847948. 
• Glavy JS, Krutchinsky AN, Cristea IM, et al. (2007). "Cell-cycle-dependent phosphorylation of the nuclear pore Nup107-160 subcomplex.". Proc. Natl. Acad. Sci. U.S.A. 104 (10): 3811–6. doi:10.1073/pnas.0700058104. PMC 1820666. PMID 17360435. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1820666. 
• Zuccolo M, Alves A, Galy V, et al. (2007). "The human Nup107-160 nuclear pore subcomplex contributes to proper kinetochore functions.". EMBO J. 26 (7): 1853–64. doi:10.1038/sj.emboj.7601642. PMC 1847668. PMID 17363900. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1847668.