TNR (gene)

Tenascin R (restrictin, janusin), also known as TNR, is a human gene.cite web | title = Entrez Gene: TNR tenascin R (restrictin, janusin)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7143| accessdate = ]

PBB_Summary
section_title =
summary_text = Tenascin-R (TNR) is an extracellular matix protein expressed primarily in the central nervous system. It is a member of the tenascin (TN) gene family, which includes at least 3 genes in mammals: TNC (or hexabrachion; MIM 187380), TNX (TNXB; MIM 600985), and TNR (Erickson, 1993). The genes are expressed in distinct tissues at different times during embryonic development and are present in adult tissues. [supplied by OMIM] cite web | title = Entrez Gene: TNR tenascin R (restrictin, janusin)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7143| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Erickson HP |title=Tenascin-C, tenascin-R and tenascin-X: a family of talented proteins in search of functions. |journal=Curr. Opin. Cell Biol. |volume=5 |issue= 5 |pages= 869–76 |year= 1993 |pmid= 7694605 |doi=
*cite journal | author=Carnemolla B, Leprini A, Borsi L, "et al." |title=Human tenascin-R. Complete primary structure, pre-mRNA alternative splicing and gene localization on chromosome 1q23-q24. |journal=J. Biol. Chem. |volume=271 |issue= 14 |pages= 8157–60 |year= 1996 |pmid= 8626505 |doi=
*cite journal | author=Leprini A, Gherzi R, Siri A, "et al." |title=The human tenascin-R gene. |journal=J. Biol. Chem. |volume=271 |issue= 49 |pages= 31251–4 |year= 1997 |pmid= 8940128 |doi=
*cite journal | author=Xiao ZC, Taylor J, Montag D, "et al." |title=Distinct effects of recombinant tenascin-R domains in neuronal cell functions and identification of the domain interacting with the neuronal recognition molecule F3/11. |journal=Eur. J. Neurosci. |volume=8 |issue= 4 |pages= 766–82 |year= 1997 |pmid= 9081628 |doi=
*cite journal | author=Aspberg A, Miura R, Bourdoulous S, "et al." |title=The C-type lectin domains of lecticans, a family of aggregating chondroitin sulfate proteoglycans, bind tenascin-R by protein-protein interactions independent of carbohydrate moiety. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=94 |issue= 19 |pages= 10116–21 |year= 1997 |pmid= 9294172 |doi=
*cite journal | author=Xiao ZC, Hillenbrand R, Schachner M, "et al." |title=Signaling events following the interaction of the neuronal adhesion molecule F3 with the N-terminal domain of tenascin-R. |journal=J. Neurosci. Res. |volume=49 |issue= 6 |pages= 698–709 |year= 1997 |pmid= 9335257 |doi=
*cite journal | author=Arrigo G, Gherzi R, Bonaglia MC, "et al." |title=Assignment of the tenascin-R gene (Tnr) to mouse chromosome 4 band E2 by fluorescence in situ hybridization; refinement of the human TNR location to chromosome 1q24. |journal=Cytogenet. Cell Genet. |volume=78 |issue= 2 |pages= 145–6 |year= 1997 |pmid= 9371410 |doi=
*cite journal | author=Volkmer H, Zacharias U, Nörenberg U, Rathjen FG |title=Dissection of complex molecular interactions of neurofascin with axonin-1, F11, and tenascin-R, which promote attachment and neurite formation of tectal cells. |journal=J. Cell Biol. |volume=142 |issue= 4 |pages= 1083–93 |year= 1998 |pmid= 9722619 |doi=
*cite journal | author=Zamze S, Harvey DJ, Pesheva P, "et al." |title=Glycosylation of a CNS-specific extracellular matrix glycoprotein, tenascin-R, is dominated by O-linked sialylated glycans and "brain-type" neutral N-glycans. |journal=Glycobiology |volume=9 |issue= 8 |pages= 823–31 |year= 1999 |pmid= 10406848 |doi=
*cite journal | author=Olin AI, Mörgelin M, Sasaki T, "et al." |title=The proteoglycans aggrecan and Versican form networks with fibulin-2 through their lectin domain binding. |journal=J. Biol. Chem. |volume=276 |issue= 2 |pages= 1253–61 |year= 2001 |pmid= 11038354 |doi= 10.1074/jbc.M006783200
*cite journal | author=Xu XR, Huang J, Xu ZG, "et al." |title=Insight into hepatocellular carcinogenesis at transcriptome level by comparing gene expression profiles of hepatocellular carcinoma with those of corresponding noncancerous liver. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=98 |issue= 26 |pages= 15089–94 |year= 2002 |pmid= 11752456 |doi= 10.1073/pnas.241522398
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Woodworth A, Pesheva P, Fiete D, Baenziger JU |title=Neuronal-specific synthesis and glycosylation of tenascin-R. |journal=J. Biol. Chem. |volume=279 |issue= 11 |pages= 10413–21 |year= 2004 |pmid= 14681222 |doi= 10.1074/jbc.M312466200
*cite journal | author=Kimura K, Wakamatsu A, Suzuki Y, "et al." |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406
*cite journal | author=Gregory SG, Barlow KF, McLay KE, "et al." |title=The DNA sequence and biological annotation of human chromosome 1. |journal=Nature |volume=441 |issue= 7091 |pages= 315–21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727
*cite journal | author=Bukalo O, Schachner M, Dityatev A |title=Hippocampal metaplasticity induced by deficiency in the extracellular matrix glycoprotein tenascin-R. |journal=J. Neurosci. |volume=27 |issue= 22 |pages= 6019–28 |year= 2007 |pmid= 17537973 |doi= 10.1523/JNEUROSCI.1022-07.2007

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