MGAT1

Mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase, also known as MGAT1, is a human gene.cite web | title = Entrez Gene: MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4245| accessdate = ]

PBB_Summary
section_title =
summary_text = There are believed to be over 100 different glycosyltransferases involved in the synthesis of protein-bound and lipid-bound oligosaccharides. UDP-N-acetylglucosamine:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I is a medial-Golgi enzyme essential for the synthesis of hybrid and complex N-glycans. The protein, encoded by a single exon, shows typical features of a type II transmembrane protein. The protein is believed to be essential for normal embryogenesis.cite web | title = Entrez Gene: MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4245| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Kumar R, Yang J, Eddy RL, "et al." |title=Cloning and expression of the murine gene and chromosomal location of the human gene encoding N-acetylglucosaminyltransferase I. |journal=Glycobiology |volume=2 |issue= 4 |pages= 383–93 |year= 1992 |pmid= 1421759 |doi=
*cite journal | author=Kumar R, Yang J, Larsen RD, Stanley P |title=Cloning and expression of N-acetylglucosaminyltransferase I, the medial Golgi transferase that initiates complex N-linked carbohydrate formation. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=87 |issue= 24 |pages= 9948–52 |year= 1991 |pmid= 1702225 |doi=
*cite journal | author=Hull E, Sarkar M, Spruijt MP, "et al." |title=Organization and localization to chromosome 5 of the human UDP-N-acetylglucosamine:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I gene. |journal=Biochem. Biophys. Res. Commun. |volume=176 |issue= 2 |pages= 608–15 |year= 1991 |pmid= 1827260 |doi=
*cite journal | author=Tan J, D'Agostaro AF, Bendiak B, "et al." |title=The human UDP-N-acetylglucosamine: alpha-6-D-mannoside-beta-1,2- N-acetylglucosaminyltransferase II gene (MGAT2). Cloning of genomic DNA, localization to chromosome 14q21, expression in insect cells and purification of the recombinant protein. |journal=Eur. J. Biochem. |volume=231 |issue= 2 |pages= 317–28 |year= 1995 |pmid= 7635144 |doi=
*cite journal | author=Yip B, Chen SH, Mulder H, "et al." |title=Organization of the human beta-1,2-N-acetylglucosaminyltransferase I gene (MGAT1), which controls complex and hybrid N-glycan synthesis. |journal=Biochem. J. |volume=321 ( Pt 2) |issue= |pages= 465–74 |year= 1997 |pmid= 9020882 |doi=
*cite journal | author=Yen CL, Stone SJ, Cases S, "et al." |title=Identification of a gene encoding MGAT1, a monoacylglycerol acyltransferase. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 13 |pages= 8512–7 |year= 2002 |pmid= 12077311 |doi= 10.1073/pnas.132274899
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Colland F, Jacq X, Trouplin V, "et al." |title=Functional proteomics mapping of a human signaling pathway. |journal=Genome Res. |volume=14 |issue= 7 |pages= 1324–32 |year= 2004 |pmid= 15231748 |doi= 10.1101/gr.2334104
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Otsuki T, Ota T, Nishikawa T, "et al." |title=Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries. |journal=DNA Res. |volume=12 |issue= 2 |pages= 117–26 |year= 2007 |pmid= 16303743 |doi= 10.1093/dnares/12.2.117
*cite journal | author=Saribas AS, Johnson K, Liu L, "et al." |title=Refolding of human beta-1-2 GlcNAc transferase (GnT1) and the role of its unpaired Cys 121. |journal=Biochem. Biophys. Res. Commun. |volume=362 |issue= 2 |pages= 381–6 |year= 2007 |pmid= 17716624 |doi= 10.1016/j.bbrc.2007.07.199

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