OSR1

Odd-skipped related 1 (Drosophila)
Identifiers
Symbols	OSR1; ODD
External IDs	OMIM: 608891 MGI: 1344424 HomoloGene: 8035 GeneCards: OSR1 Gene
Gene Ontology Molecular function • nucleic acid binding • zinc ion binding • metal ion binding Cellular component • intracellular • nucleus • nucleolus Biological process • negative regulation of transcription from RNA polymerase II promoter • urogenital system development • ureteric bud development • mesonephros development • chondrocyte differentiation • regulation of transcription, DNA-dependent • heart development • gonad development • positive regulation of gene expression • cell differentiation • positive regulation of bone mineralization • negative regulation of epithelial cell differentiation • embryonic forelimb morphogenesis • embryonic hindlimb morphogenesis • middle ear morphogenesis • odontogenesis • embryonic digit morphogenesis • negative regulation of apoptosis • positive regulation of transcription from RNA polymerase II promoter • embryonic leg joint morphogenesis • intermediate mesoderm development • pronephros development • stem cell differentiation • positive regulation of epithelial cell proliferation • palate development • embryonic skeletal joint morphogenesis • metanephric mesenchyme development • cell proliferation involved in kidney development • metanephric mesenchyme morphogenesis • mesangial cell development • metanephric mesenchymal cell differentiation • posterior mesonephric tubule development • specification of anterior mesonephric tubule identity • specification of posterior mesonephric tubule identity • mesonephric duct morphogenesis • negative regulation of nephron tubule epithelial cell differentiation • renal vesicle progenitor cell differentiation • ureter urothelium development • metanephric epithelium development • metanephric smooth muscle tissue development • metanephric nephron tubule development • metanephric glomerulus vasculature development • metanephric interstitial cell development • pattern specification involved in metanephros development • embryonic skeletal joint development • metanephric cap mesenchymal cell proliferation involved in metanephros development • positive regulation of gastrulation Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	130497	23967
Ensembl	ENSG00000143867	ENSMUSG00000048387
UniProt	Q8TAX0	Q9WVG7
RefSeq (mRNA)	NM_145260	NM_011859.3
RefSeq (protein)	NP_660303	NP_035989.1
Location (UCSC)	Chr 2: 19.55 – 19.56 Mb	Chr 12: 9.58 – 9.59 Mb
PubMed search	[1]	[2]

Protein odd-skipped-related 1 is a protein that in humans is encoded by the OSR1 gene.^[1][2][3]

References

1. ^ Coulter DE, Swaykus EA, Beran-Koehn MA, Goldberg D, Wieschaus E, Schedl P (Nov 1990). "Molecular analysis of odd-skipped, a zinc finger encoding segmentation gene with a novel pair-rule expression pattern". EMBO J 9 (11): 3795–804. PMC 552139. PMID 2120051. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=552139. 
2. ^ Katoh M (Jul 2002). "Molecular cloning and characterization of OSR1 on human chromosome 2p24". Int J Mol Med 10 (2): 221–5. PMID 12119563. 
3. ^ "Entrez Gene: OSR1 odd-skipped related 1 (Drosophila)". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=130497. 

Further reading

• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination.". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=310948. 
• Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing.". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1083732. 
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241. 
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=528928. 
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline.". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=528930. 
• Barrios-Rodiles M, Brown KR, Ozdamar B, et al. (2005). "High-throughput mapping of a dynamic signaling network in mammalian cells.". Science 307 (5715): 1621–5. doi:10.1126/science.1105776. PMID 15761153. 
• Hillier LW, Graves TA, Fulton RS, et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4.". Nature 434 (7034): 724–31. doi:10.1038/nature03466. PMID 15815621. 
• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006.". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1347501. 

External links

• MeSH OSR1+protein,+human

This article incorporates text from the United States National Library of Medicine, which is in the public domain.