HOXC10

Homeobox C10, also known as HOXC10, is a human gene.cite web | title = Entrez Gene: HOXC10 homeobox C10| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3226| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The protein level is controlled during cell differentiation and proliferation, which may indicate this protein has a role in origin activation.cite web | title = Entrez Gene: HOXC10 homeobox C10| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3226| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Scott MP |title=Vertebrate homeobox gene nomenclature. |journal=Cell |volume=71 |issue= 4 |pages= 551–3 |year= 1992 |pmid= 1358459 |doi=
*cite journal | author=Acampora D, D'Esposito M, Faiella A, "et al." |title=The human HOX gene family. |journal=Nucleic Acids Res. |volume=17 |issue= 24 |pages= 10385–402 |year= 1990 |pmid= 2574852 |doi=
*cite journal | author=Rabin M, Ferguson-Smith A, Hart CP, Ruddle FH |title=Cognate homeo-box loci mapped on homologous human and mouse chromosomes. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=83 |issue= 23 |pages= 9104–8 |year= 1987 |pmid= 2878432 |doi=
*cite journal | author=Apiou F, Flagiello D, Cillo C, "et al." |title=Fine mapping of human HOX gene clusters. |journal=Cytogenet. Cell Genet. |volume=73 |issue= 1-2 |pages= 114–5 |year= 1996 |pmid= 8646877 |doi=
*cite journal | author=Flagiello D, Gibaud A, Dutrillaux B, "et al." |title=Distinct patterns of all-trans retinoic acid dependent expression of HOXB and HOXC homeogenes in human embryonal and small-cell lung carcinoma cell lines. |journal=FEBS Lett. |volume=415 |issue= 3 |pages= 263–7 |year= 1997 |pmid= 9357979 |doi=
*cite journal | author=de Stanchina E, Gabellini D, Norio P, "et al." |title=Selection of homeotic proteins for binding to a human DNA replication origin. |journal=J. Mol. Biol. |volume=299 |issue= 3 |pages= 667–80 |year= 2000 |pmid= 10835276 |doi= 10.1006/jmbi.2000.3782
*cite journal | author=Sandrock B, Egly JM |title=A yeast four-hybrid system identifies Cdk-activating kinase as a regulator of the XPD helicase, a subunit of transcription factor IIH. |journal=J. Biol. Chem. |volume=276 |issue= 38 |pages= 35328–33 |year= 2001 |pmid= 11445587 |doi= 10.1074/jbc.M105570200
*cite journal | author=Kosaki K, Kosaki R, Suzuki T, "et al." |title=Complete mutation analysis panel of the 39 human HOX genes. |journal=Teratology |volume=65 |issue= 2 |pages= 50–62 |year= 2002 |pmid= 11857506 |doi= 10.1002/tera.10009
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Gabellini D, Colaluca IN, Vodermaier HC, "et al." |title=Early mitotic degradation of the homeoprotein HOXC10 is potentially linked to cell cycle progression. |journal=EMBO J. |volume=22 |issue= 14 |pages= 3715–24 |year= 2003 |pmid= 12853486 |doi= 10.1093/emboj/cdg340
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Zhai Y, Kuick R, Nan B, "et al." |title=Gene expression analysis of preinvasive and invasive cervical squamous cell carcinomas identifies HOXC10 as a key mediator of invasion. |journal=Cancer Res. |volume=67 |issue= 21 |pages= 10163–72 |year= 2007 |pmid= 17974957 |doi= 10.1158/0008-5472.CAN-07-2056

External links

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