ZIC1

ZIC1

Zic family member 1 (odd-paired homolog, Drosophila), also known as ZIC1, is a human gene.cite web | title = Entrez Gene: ZIC1 Zic family member 1 (odd-paired homolog, Drosophila)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7545| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. Members of this family are important during development. Aberrant expression of this gene is seen in medulloblastoma, a childhood brain tumor. This gene is closely linked to the gene encoding zinc finger protein of the cerebellum 4, a related family member on chromosome 3. This gene encodes a transcription factor that can bind and transactivate the apolipoprotein E gene.cite web | title = Entrez Gene: ZIC1 Zic family member 1 (odd-paired homolog, Drosophila)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7545| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Yokota N, Aruga J, Takai S, "et al." |title=Predominant expression of human zic in cerebellar granule cell lineage and medulloblastoma. |journal=Cancer Res. |volume=56 |issue= 2 |pages= 377–83 |year= 1996 |pmid= 8542595 |doi=
*cite journal | author=Andersson B, Wentland MA, Ricafrente JY, "et al." |title=A "double adaptor" method for improved shotgun library construction. |journal=Anal. Biochem. |volume=236 |issue= 1 |pages= 107–13 |year= 1996 |pmid= 8619474 |doi= 10.1006/abio.1996.0138
*cite journal | author=Yu W, Andersson B, Worley KC, "et al." |title=Large-scale concatenation cDNA sequencing. |journal=Genome Res. |volume=7 |issue= 4 |pages= 353–8 |year= 1997 |pmid= 9110174 |doi=
*cite journal | author=Dias Neto E, Correa RG, Verjovski-Almeida S, "et al." |title=Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=97 |issue= 7 |pages= 3491–6 |year= 2000 |pmid= 10737800 |doi=
*cite journal | author=Michiels EM, Oussoren E, Van Groenigen M, "et al." |title=Genes differentially expressed in medulloblastoma and fetal brain. |journal=Physiol. Genomics |volume=1 |issue= 2 |pages= 83–91 |year= 2000 |pmid= 11015565 |doi=
*cite journal | author=Salero E, Pérez-Sen R, Aruga J, "et al." |title=Transcription factors Zic1 and Zic2 bind and transactivate the apolipoprotein E gene promoter. |journal=J. Biol. Chem. |volume=276 |issue= 3 |pages= 1881–8 |year= 2001 |pmid= 11038359 |doi= 10.1074/jbc.M007008200
*cite journal | author=Koyabu Y, Nakata K, Mizugishi K, "et al." |title=Physical and functional interactions between Zic and Gli proteins. |journal=J. Biol. Chem. |volume=276 |issue= 10 |pages= 6889–92 |year= 2001 |pmid= 11238441 |doi= 10.1074/jbc.C000773200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Bagutti C, Forro G, Ferralli J, "et al." |title=The intracellular domain of teneurin-2 has a nuclear function and represses zic-1-mediated transcription. |journal=J. Cell. Sci. |volume=116 |issue= Pt 14 |pages= 2957–66 |year= 2004 |pmid= 12783990 |doi= 10.1242/jcs.00603
*cite journal | author=Bennett CL, Parisi MA, Eckert ML, "et al." |title=Joubert syndrome: a haplotype segregation strategy and exclusion of the zinc finger protein of cerebellum 1 (ZIC1) gene. |journal=Am. J. Med. Genet. A |volume=125 |issue= 2 |pages= 117–24; discussion 117 |year= 2004 |pmid= 14981711 |doi= 10.1002/ajmg.a.20438
*cite journal | author=Grinberg I, Northrup H, Ardinger H, "et al." |title=Heterozygous deletion of the linked genes ZIC1 and ZIC4 is involved in Dandy-Walker malformation. |journal=Nat. Genet. |volume=36 |issue= 10 |pages= 1053–5 |year= 2004 |pmid= 15338008 |doi= 10.1038/ng1420
*cite journal | author=Pourebrahim R, Van Dam K, Bauters M, "et al." |title=ZIC1 gene expression is controlled by DNA and histone methylation in mesenchymal proliferations. |journal=FEBS Lett. |volume=581 |issue= 26 |pages= 5122–6 |year= 2007 |pmid= 17936758 |doi= 10.1016/j.febslet.2007.09.061

PBB_Controls
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