KCNK5

Potassium channel, subfamily K, member 5, also known as KCNK5, is a human gene.cite web | title = Entrez Gene: KCNK5 potassium channel, subfamily K, member 5| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8645| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The message for this gene is mainly expressed in the cortical distal tubules and collecting ducts of the kidney. The protein is highly sensitive to external pH and this, in combination with its expression pattern, suggests it may play an important role in renal potassium transport.cite web | title = Entrez Gene: KCNK5 potassium channel, subfamily K, member 5| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8645| accessdate = ]

ee also

* Tandem pore domain potassium channel

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Goldstein SA, Bockenhauer D, O'Kelly I, Zilberberg N |title=Potassium leak channels and the KCNK family of two-P-domain subunits. |journal=Nat. Rev. Neurosci. |volume=2 |issue= 3 |pages= 175–84 |year= 2001 |pmid= 11256078 |doi=
*cite journal | author=Goldstein SA, Bayliss DA, Kim D, "et al." |title=International Union of Pharmacology. LV. Nomenclature and molecular relationships of two-P potassium channels. |journal=Pharmacol. Rev. |volume=57 |issue= 4 |pages= 527–40 |year= 2006 |pmid= 16382106 |doi= 10.1124/pr.57.4.12
*cite journal | author=Bonaldo MF, Lennon G, Soares MB |title=Normalization and subtraction: two approaches to facilitate gene discovery. |journal=Genome Res. |volume=6 |issue= 9 |pages= 791–806 |year= 1997 |pmid= 8889548 |doi=
*cite journal | author=Reyes R, Duprat F, Lesage F, "et al." |title=Cloning and expression of a novel pH-sensitive two pore domain K+ channel from human kidney. |journal=J. Biol. Chem. |volume=273 |issue= 47 |pages= 30863–9 |year= 1998 |pmid= 9812978 |doi=
*cite journal | author=Gray AT, Zhao BB, Kindler CH, "et al." |title=Volatile anesthetics activate the human tandem pore domain baseline K+ channel KCNK5. |journal=Anesthesiology |volume=92 |issue= 6 |pages= 1722–30 |year= 2000 |pmid= 10839924 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Morton MJ, O'Connell AD, Sivaprasadarao A, Hunter M |title=Determinants of pH sensing in the two-pore domain K(+) channels TASK-1 and -2. |journal=Pflugers Arch. |volume=445 |issue= 5 |pages= 577–83 |year= 2003 |pmid= 12634929 |doi= 10.1007/s00424-002-0901-2
*cite journal | author=Niemeyer MI, Cid LP, Valenzuela X, "et al." |title=Extracellular conserved cysteine forms an intersubunit disulphide bridge in the KCNK5 (TASK-2) K+ channel without having an essential effect upon activity. |journal=Mol. Membr. Biol. |volume=20 |issue= 2 |pages= 185–91 |year= 2004 |pmid= 12851074 |doi= 10.1080/0968768031000084181
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Rusznák Z, Pocsai K, Kovács I, "et al." |title=Differential distribution of TASK-1, TASK-2 and TASK-3 immunoreactivities in the rat and human cerebellum. |journal=Cell. Mol. Life Sci. |volume=61 |issue= 12 |pages= 1532–42 |year= 2004 |pmid= 15197476 |doi= 10.1007/s00018-004-4082-3
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504

External links

*

PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes