- UGT2B17
UDP glucuronosyltransferase 2 family, polypeptide B17, also known as UGT2B17, is a human
gene .cite web | title = Entrez Gene: UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7367| accessdate = ]PBB_Summary
section_title =
summary_text = UGT2B17 belongs to the family of UDP-glucuronosyltransferases (UGTs; EC 2.4.1.17), enzymes that catalyze the transfer of glucuronic acid from uridine diphosphoglucuronic acid to a variety of substrates, including steroid hormones. [supplied by OMIM] cite web | title = Entrez Gene: UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7367| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Chung LW, Coffey DS |title=Androgen glucuronide. II. DIfferences in its formation by human normal and benign hyperplastic prostates. |journal=Investigative urology |volume=15 |issue= 5 |pages= 385–8 |year= 1978 |pmid= 76619 |doi=
*cite journal | author=Moghissi E, Ablan F, Horton R |title=Origin of plasma androstanediol glucuronide in men. |journal=J. Clin. Endocrinol. Metab. |volume=59 |issue= 3 |pages= 417–21 |year= 1984 |pmid= 6746859 |doi=
*cite journal | author=Beaulieu M, Lévesque E, Hum DW, Bélanger A |title=Isolation and characterization of a novel cDNA encoding a human UDP-glucuronosyltransferase active on C19 steroids. |journal=J. Biol. Chem. |volume=271 |issue= 37 |pages= 22855–62 |year= 1996 |pmid= 8798464 |doi=
*cite journal | author=Beaulieu M, Lévesque E, Tchernof A, "et al." |title=Chromosomal localization, structure, and regulation of the UGT2B17 gene, encoding a C19 steroid metabolizing enzyme. |journal=DNA Cell Biol. |volume=16 |issue= 10 |pages= 1143–54 |year= 1997 |pmid= 9364925 |doi=
*cite journal | author=Collier AC, Ganley NA, Tingle MD, "et al." |title=UDP-glucuronosyltransferase activity, expression and cellular localization in human placenta at term. |journal=Biochem. Pharmacol. |volume=63 |issue= 3 |pages= 409–19 |year= 2002 |pmid= 11853692 |doi=
*cite journal | author=Chouinard S, Pelletier G, Bélanger A, Barbier O |title=Cellular specific expression of the androgen-conjugating enzymes UGT2B15 and UGT2B17 in the human prostate epithelium. |journal=Endocr. Res. |volume=30 |issue= 4 |pages= 717–25 |year= 2005 |pmid= 15666817 |doi=
*cite journal | author=Lazarus P, Zheng Y, Aaron Runkle E, "et al." |title=Genotype-phenotype correlation between the polymorphic UGT2B17 gene deletion and NNAL glucuronidation activities in human liver microsomes. |journal=Pharmacogenet. Genomics |volume=15 |issue= 11 |pages= 769–78 |year= 2006 |pmid= 16220109 |doi=
*cite journal | author=Jakobsson J, Ekström L, Inotsume N, "et al." |title=Large differences in testosterone excretion in Korean and Swedish men are strongly associated with a UDP-glucuronosyl transferase 2B17 polymorphism. |journal=J. Clin. Endocrinol. Metab. |volume=91 |issue= 2 |pages= 687–93 |year= 2006 |pmid= 16332934 |doi= 10.1210/jc.2005-1643
*cite journal | author=Park J, Chen L, Ratnashinge L, "et al." |title=Deletion polymorphism of UDP-glucuronosyltransferase 2B17 and risk of prostate cancer in African American and Caucasian men. |journal=Cancer Epidemiol. Biomarkers Prev. |volume=15 |issue= 8 |pages= 1473–8 |year= 2006 |pmid= 16896035 |doi= 10.1158/1055-9965.EPI-06-0141
*cite journal | author=Gallagher CJ, Muscat JE, Hicks AN, "et al." |title=The UDP-glucuronosyltransferase 2B17 gene deletion polymorphism: sex-specific association with urinary 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol glucuronidation phenotype and risk for lung cancer. |journal=Cancer Epidemiol. Biomarkers Prev. |volume=16 |issue= 4 |pages= 823–8 |year= 2007 |pmid= 17416778 |doi= 10.1158/1055-9965.EPI-06-0823
*cite journal | author=Park JY, Tanner JP, Sellers TA, "et al." |title=Association between polymorphisms in HSD3B1 and UGT2B17 and prostate cancer risk. |journal=Urology |volume=70 |issue= 2 |pages= 374–9 |year= 2007 |pmid= 17826523 |doi= 10.1016/j.urology.2007.03.001
*cite journal | author=Chouinard S, Barbier O, Bélanger A |title=UDP-glucuronosyltransferase 2B15 (UGT2B15) and UGT2B17 enzymes are major determinants of the androgen response in prostate cancer LNCaP cells. |journal=J. Biol. Chem. |volume=282 |issue= 46 |pages= 33466–74 |year= 2008 |pmid= 17848572 |doi= 10.1074/jbc.M703370200PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes
Wikimedia Foundation. 2010.
