- ADAM8
ADAM metallopeptidase domain 8, also known as ADAM8, is a human
gene .cite web | title = Entrez Gene: ADAM8 ADAM metallopeptidase domain 8| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=101| accessdate = ]PBB_Summary
section_title =
summary_text = This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene may be involved in cell adhesion during neurodegeneration.cite web | title = Entrez Gene: ADAM8 ADAM metallopeptidase domain 8| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=101| accessdate = ]ee also
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Cluster of differentiation References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Yamamoto S, Higuchi Y, Yoshiyama K, "et al." |title=ADAM family proteins in the immune system. |journal=Immunol. Today |volume=20 |issue= 6 |pages= 278–84 |year= 1999 |pmid= 10354553 |doi=
*cite journal | author=Yoshiyama K, Higuchi Y, Kataoka M, "et al." |title=CD156 (human ADAM8): expression, primary amino acid sequence, and gene location. |journal=Genomics |volume=41 |issue= 1 |pages= 56–62 |year= 1997 |pmid= 9126482 |doi= 10.1006/geno.1997.4607
*cite journal | author=Schlomann U, Rathke-Hartlieb S, Yamamoto S, "et al." |title=Tumor necrosis factor alpha induces a metalloprotease-disintegrin, ADAM8 (CD 156): implications for neuron-glia interactions during neurodegeneration. |journal=J. Neurosci. |volume=20 |issue= 21 |pages= 7964–71 |year= 2001 |pmid= 11050116 |doi=
*cite journal | author=Amour A, Knight CG, English WR, "et al." |title=The enzymatic activity of ADAM8 and ADAM9 is not regulated by TIMPs. |journal=FEBS Lett. |volume=524 |issue= 1-3 |pages= 154–8 |year= 2002 |pmid= 12135759 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Ishikawa N, Daigo Y, Yasui W, "et al." |title=ADAM8 as a novel serological and histochemical marker for lung cancer. |journal=Clin. Cancer Res. |volume=10 |issue= 24 |pages= 8363–70 |year= 2005 |pmid= 15623614 |doi= 10.1158/1078-0432.CCR-04-1436
*cite journal | author=Kimura K, Wakamatsu A, Suzuki Y, "et al." |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406
*cite journal | author=Foley SC, Mogas AK, Olivenstein R, "et al." |title=Increased expression of ADAM33 and ADAM8 with disease progression in asthma. |journal=J. Allergy Clin. Immunol. |volume=119 |issue= 4 |pages= 863–71 |year= 2007 |pmid= 17339047 |doi= 10.1016/j.jaci.2006.12.665
*cite journal | author=Gómez-Gaviro M, Domínguez-Luis M, Canchado J, "et al." |title=Expression and regulation of the metalloproteinase ADAM-8 during human neutrophil pathophysiological activation and its catalytic activity on L-selectin shedding. |journal=J. Immunol. |volume=178 |issue= 12 |pages= 8053–63 |year= 2007 |pmid= 17548643 |doi=
*cite journal | author=Valkovskaya N, Kayed H, Felix K, "et al." |title=ADAM8 expression is associated with increased invasiveness and reduced patient survival in pancreatic cancer. |journal=J. Cell. Mol. Med. |volume=11 |issue= 5 |pages= 1162–74 |year= 2008 |pmid= 17979891 |doi= 10.1111/j.1582-4934.2007.00082.xPBB_Controls
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