Toxoid

Toxoid

A toxoid is a bacterial toxin (usually an exotoxin)whose toxicity has been weakened or suppressed either by chemical (formalin) or heat treatment, while other properties, typically immunogenicity, are maintained. Toxoids are used in vaccines as they induce an immune response to the original toxin or increase the response to another antigen.For example, the tetanus toxoid is derived from the tetanospasmin produced by "Clostridium tetani" and causing tetanus. The tetanus toxoid is used by many plasma centers in the United States for the development of plasma rich vaccines.


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  • Toxoid — Tox oid, n. [Toxin + oid.] (Physiol. Chem.) An altered form of a toxin, possessing little or no toxic power. [Webster 1913 Suppl.] …   The Collaborative International Dictionary of English

  • toxoid — [täk′soid΄] n. [ TOX(IN) + OID] a toxin that has been treated, as with chemicals or heat, so as to eliminate the toxic qualities while retaining the antigenic properties …   English World dictionary

  • Toxoid — Toxoidimpfstoffe sind Impfstoffe, die Toxoide als wirksamen Bestandteil enthalten und bei aktiven Impfungen eingesetzt werden. Toxoide sind entgiftete Toxine, bei denen durch spezielle Verfahren die für die Giftigkeit verantwortlichen… …   Deutsch Wikipedia

  • toxoid — /tok soyd/ n. a toxin rendered nontoxic by treatment with chemical agents or by physical means and used for administration into the body in order to produce specific immunity by stimulating the production of antibodies. Also called anatoxin.… …   Universalium

  • toxoid — A toxin that has been treated (commonly with formaldehyde) so as to destroy its toxic property but retain its antigenicity, i.e., its capability of stimulating the production of antitoxin antibodies and thus of producing an active immunity.For… …   Medical dictionary

  • Toxoid — To|xo|id 〈n. 11〉 entgiftetes Toxin, das im menschl. Körper keine Schäden, aber die Bildung von Antitoxinen bewirkt [→ Toxikum] * * * To|xo|id [↑ Toxin u. ↑ oid], das; s, e; veraltetes Syn.: Anatoxin: ein durch Zerstörung der toxophoren Gruppe… …   Universal-Lexikon

  • toxoid — noun a bacterial toxin that has been weakened until it is no longer toxic but is strong enough to induce the formation of antibodies and immunity to the specific disease caused by the toxin diphtheria toxoid • Syn: ↑anatoxin • Hypernyms:… …   Useful english dictionary

  • toxoid-antitoxin floccule — a suspension of the precipitate formed when toxoid and antitoxin are mixed …   Medical dictionary

  • toxoid-antitoxoid — tox·oid an·ti·tox·oid (tok″soid anґtĭ tok″soid) a toxoid mixed with an equivalent amount of antitoxic serum, the precipitate being suspended in saline …   Medical dictionary

  • toxoid — noun Etymology: International Scientific Vocabulary Date: circa 1894 a toxin of a pathogenic organism treated so as to destroy its toxicity but leave it capable of inducing the formation of antibodies on injection …   New Collegiate Dictionary

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