Levophenacylmorphan

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IUPAC_name = (-)-3-Hydroxy-N-phenacylmorphinan

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width = 200
CAS_number = 10061-32-2
synonyms = Levophenacylmorphan
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PubChem = 5362482
smiles = C1CC [C@@] 23CCN( [C@@H] ( [C@@H] 2C1)CC4=C3C=C(C=C4)O)CC(=O)C5=CC=CC=C5
DrugBank =
C = 24 | H = 27 | N = 1 | O = 2
molecular_weight = 361.48 g/mol
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legal_US = Schedule I
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Levophenacylmorphan is a morphinan derivative that acts as an opioid agonist. It has potent analgesic effects and is around 10x more potent than morphine. [MAY, E.L. & EDDY, N.B., A New Potent Synthetic Analgesic, J. Org. Chem., 24 : 294, 1959.] It also produces all the normal opioid side effects such as itching, nausea, respiratory depression, and development of tolerance and dependence to its effects. [ [http://www.unodc.org/unodc/en/data-and-analysis/bulletin/bulletin_1960-01-01_2_page004.html Fraser HF, Isbell H. Human pharmacology and addiction liabilities of phenazocine and levophenacylmorphan. "UN Bulletin on Narcotics". 1960 Issue 2] ]

References