Tropane alkaloid


Tropane alkaloid

Tropane alkaloids, also known as "Belladonna" alkaloids are a class of alkaloids and secondary metabolites that contain a tropane ring in their chemical structure. Tropane alkaloids occur naturally in many members of the plant family Solanaceae.

Important tropane alkaloids are:

Anticholinergics

Anticholinergic drugs and deliriants:

* Atropine, racemic hyoscyamine, from the deadly nightshade ("Atropa belladonna")
* Hyoscyamine, the "levo"-isomer of atropine, from henbane ("Hyoscamus niger") and mandrake ("Mandragora officinalis")
* Scopolamine, from henbane and "Datura" species (Jimson weed)

Stimulants

Stimulants and cocaine-related alkaloids:

* Cocaine, from "Erythroxylum coca"
* Ecgonidine, and methylecgonidine, pyrolysis products of cocaine
* Ecgonine, a precursor and metabolite of cocaine
* Benzoylecgonine, a metabolite of cocaine
* Cocaethylene, a metabolite of cocaine
* Hydroxytropacocaine, from "Erythroxylum coca"
* Methylecgonine cinnamate, from "Erythroxylum coca"

Others

* Catuabines, found in the drug catuaba, from "Erythroxylum vacciniifolium"

Non-natural tropanes

* Phenyltropanes

See also

* Alkaloid
* Tropane


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