BTN2A2

BTN2A2

Butyrophilin, subfamily 2, member A2, also known as BTN2A2, is a human gene.cite web | title = Entrez Gene: BTN2A2 butyrophilin, subfamily 2, member A2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10385| accessdate = ]

PBB_Summary
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summary_text = Butyrophilin is the major protein associated with fat droplets in the milk. This gene is a member of the BTN2 subfamily of genes, which encode proteins belonging to the butyrophilin protein family. The gene is located in a cluster on chromosome 6, consisting of seven genes belonging to the expanding B7/butyrophilin-like group, a subset of the immunoglobulin gene superfamily. The encoded protein is a type 1 receptor glycoprotein involved in lipid, fatty-acid and sterol metabolism. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined.cite web | title = Entrez Gene: BTN2A2 butyrophilin, subfamily 2, member A2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10385| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Henry J, Miller MM, Pontarotti P |title=Structure and evolution of the extended B7 family. |journal=Immunol. Today |volume=20 |issue= 6 |pages= 285–8 |year= 1999 |pmid= 10354554 |doi=
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Mungall AJ, Palmer SA, Sims SK, "et al." |title=The DNA sequence and analysis of human chromosome 6. |journal=Nature |volume=425 |issue= 6960 |pages= 805–11 |year= 2003 |pmid= 14574404 |doi= 10.1038/nature02055
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Cavaletto M, Giuffrida MG, Fortunato D, "et al." |title=A proteomic approach to evaluate the butyrophilin gene family expression in human milk fat globule membrane. |journal=Proteomics |volume=2 |issue= 7 |pages= 850–6 |year= 2003 |pmid= 12124930 |doi= 10.1002/1615-9861(200207)2:7<850::AID-PROT850>3.0.CO;2-C |doilabel=10.1002/1615-9861(200207)2:7850::AID-PROT8503.0.CO;2-C
*cite journal | author=Rhodes DA, Stammers M, Malcherek G, "et al." |title=The cluster of BTN genes in the extended major histocompatibility complex. |journal=Genomics |volume=71 |issue= 3 |pages= 351–62 |year= 2001 |pmid= 11170752 |doi= 10.1006/geno.2000.6406
*cite journal | author=Ruddy DA, Kronmal GS, Lee VK, "et al." |title=A 1.1-Mb transcript map of the hereditary hemochromatosis locus. |journal=Genome Res. |volume=7 |issue= 5 |pages= 441–56 |year= 1997 |pmid= 9149941 |doi=

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