CTCFL

CCCTC-binding factor (zinc finger protein)-like, also known as CTCFL, is a human gene.cite web | title = Entrez Gene: CTCFL CCCTC-binding factor (zinc finger protein)-like| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=140690| accessdate = ]

PBB_Summary
section_title =
summary_text = CCCTC-binding factor (CTCF), an 11-zinc-finger factor involved in gene regulation, utilizes different zinc fingers to bind varying DNA target sites. CTCF forms methylation-sensitive insulators that regulate X-chromosome inactivation. This gene is a paralog of CTCF and appears to be expressed primarily in the cytoplasm of spermatocytes, unlike CTCF which is expressed primarily in the nucleus of somatic cells. CTCF and the protein encoded by this gene are normally expressed in a mutually exclusive pattern that correlates with resetting of methylation marks during male germ cell differentiation.cite web | title = Entrez Gene: CTCFL CCCTC-binding factor (zinc finger protein)-like| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=140690| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Klenova EM, Morse HC, Ohlsson R, Lobanenkov VV |title=The novel BORIS + CTCF gene family is uniquely involved in the epigenetics of normal biology and cancer. |journal=Semin. Cancer Biol. |volume=12 |issue= 5 |pages= 399–414 |year= 2003 |pmid= 12191639 |doi=
*cite journal | author=D'Arcy V, Pore N, Docquier F, "et al." |title=BORIS, a paralogue of the transcription factor, CTCF, is aberrantly expressed in breast tumours. |journal=Br. J. Cancer |volume=98 |issue= 3 |pages= 571–9 |year= 2008 |pmid= 18195709 |doi= 10.1038/sj.bjc.6604181
*cite journal | author=Woloszynska-Read A, James SR, Link PA, "et al." |title=DNA methylation-dependent regulation of BORIS/CTCFL expression in ovarian cancer. |journal=Cancer Immun. |volume=7 |issue= |pages= 21 |year= 2008 |pmid= 18095639 |doi=
*cite journal | author=Renaud S, Pugacheva EM, Delgado MD, "et al." |title=Expression of the CTCF-paralogous cancer-testis gene, brother of the regulator of imprinted sites (BORIS), is regulated by three alternative promoters modulated by CpG methylation and by CTCF and p53 transcription factors. |journal=Nucleic Acids Res. |volume=35 |issue= 21 |pages= 7372–88 |year= 2008 |pmid= 17962299 |doi= 10.1093/nar/gkm896
*cite journal | author=Kholmanskikh O, Loriot A, Brasseur F, "et al." |title=Expression of BORIS in melanoma: lack of association with MAGE-A1 activation. |journal=Int. J. Cancer |volume=122 |issue= 4 |pages= 777–84 |year= 2008 |pmid= 17957795 |doi= 10.1002/ijc.23140
*cite journal | author=Risinger JI, Chandramouli GV, Maxwell GL, "et al." |title=Global expression analysis of cancer/testis genes in uterine cancers reveals a high incidence of BORIS expression. |journal=Clin. Cancer Res. |volume=13 |issue= 6 |pages= 1713–9 |year= 2007 |pmid= 17363524 |doi= 10.1158/1078-0432.CCR-05-2569
*cite journal | author=D'Arcy V, Abdullaev ZK, Pore N, "et al." |title=The potential of BORIS detected in the leukocytes of breast cancer patients as an early marker of tumorigenesis. |journal=Clin. Cancer Res. |volume=12 |issue= 20 Pt 1 |pages= 5978–86 |year= 2006 |pmid= 17062669 |doi= 10.1158/1078-0432.CCR-05-2731
*cite journal | author=Hoffmann MJ, Müller M, Engers R, Schulz WA |title=Epigenetic control of CTCFL/BORIS and OCT4 expression in urogenital malignancies. |journal=Biochem. Pharmacol. |volume=72 |issue= 11 |pages= 1577–88 |year= 2007 |pmid= 16854382 |doi= 10.1016/j.bcp.2006.06.020
*cite journal | author=Hong JA, Kang Y, Abdullaev Z, "et al." |title=Reciprocal binding of CTCF and BORIS to the NY-ESO-1 promoter coincides with derepression of this cancer-testis gene in lung cancer cells. |journal=Cancer Res. |volume=65 |issue= 17 |pages= 7763–74 |year= 2005 |pmid= 16140944 |doi= 10.1158/0008-5472.CAN-05-0823
*cite journal | author=Rodriguez M, Yu X, Chen J, Songyang Z |title=Phosphopeptide binding specificities of BRCA1 COOH-terminal (BRCT) domains. |journal=J. Biol. Chem. |volume=278 |issue= 52 |pages= 52914–8 |year= 2004 |pmid= 14578343 |doi= 10.1074/jbc.C300407200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Loukinov DI, Pugacheva E, Vatolin S, "et al." |title=BORIS, a novel male germ-line-specific protein associated with epigenetic reprogramming events, shares the same 11-zinc-finger domain with CTCF, the insulator protein involved in reading imprinting marks in the soma. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 10 |pages= 6806–11 |year= 2002 |pmid= 12011441 |doi= 10.1073/pnas.092123699
*cite journal | author=Deloukas P, Matthews LH, Ashurst J, "et al." |title=The DNA sequence and comparative analysis of human chromosome 20. |journal=Nature |volume=414 |issue= 6866 |pages= 865–71 |year= 2002 |pmid= 11780052 |doi= 10.1038/414865a

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