ALOXE3

Arachidonate lipoxygenase 3, also known as ALOXE3, is a human gene.cite web | title = Entrez Gene: ALOXE3 arachidonate lipoxygenase 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=59344| accessdate = ]

PBB_Summary
section_title =
summary_text = The leukotrienes constitute a group of arachidonic acid-derived compounds with biologic activities suggesting important roles in inflammation and immediate hypersensitivity. These compounds are catabolized, in part, by lipoxygenases. Epidermis-type lipoxygenases, a distinct subclass within the multigene family of mammalian lipoxygenases, are novel isoenzymes isolated from human and mouse skin including human ALOX15B (MIM 603697), human and mouse ALOX12B (MIM 603741), mouse 8S-LOX, and mouse e-LOX-3. [supplied by OMIM] cite web | title = Entrez Gene: ALOXE3 arachidonate lipoxygenase 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=59344| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Yu Z, Schneider C, Boeglin WE, Brash AR |title=Epidermal lipoxygenase products of the hepoxilin pathway selectively activate the nuclear receptor PPARalpha. |journal=Lipids |volume=42 |issue= 6 |pages= 491-7 |year= 2007 |pmid= 17436029 |doi= 10.1007/s11745-007-3054-4
*cite journal | author=Lesueur F, Bouadjar B, Lefèvre C, "et al." |title=Novel mutations in ALOX12B in patients with autosomal recessive congenital ichthyosis and evidence for genetic heterogeneity on chromosome 17p13. |journal=J. Invest. Dermatol. |volume=127 |issue= 4 |pages= 829-34 |year= 2007 |pmid= 17139268 |doi= 10.1038/sj.jid.5700640
*cite journal | author=Yu Z, Schneider C, Boeglin WE, Brash AR |title=Human and mouse eLOX3 have distinct substrate specificities: implications for their linkage with lipoxygenases in skin. |journal=Arch. Biochem. Biophys. |volume=455 |issue= 2 |pages= 188-96 |year= 2007 |pmid= 17045234 |doi= 10.1016/j.abb.2006.09.002
*cite journal | author=Yu Z, Schneider C, Boeglin WE, Brash AR |title=Mutations associated with a congenital form of ichthyosis (NCIE) inactivate the epidermal lipoxygenases 12R-LOX and eLOX3. |journal=Biochim. Biophys. Acta |volume=1686 3 |issue= |pages= 238-47 |year= 2005 |pmid= 15629692 |doi= 10.1016/j.bbalip.2004.10.007
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Jobard F, Lefèvre C, Karaduman A, "et al." |title=Lipoxygenase-3 (ALOXE3) and 12(R)-lipoxygenase (ALOX12B) are mutated in non-bullous congenital ichthyosiform erythroderma (NCIE) linked to chromosome 17p13.1. |journal=Hum. Mol. Genet. |volume=11 |issue= 1 |pages= 107-13 |year= 2002 |pmid= 11773004 |doi=
*cite journal | author=Krieg P, Marks F, Fürstenberger G |title=A gene cluster encoding human epidermis-type lipoxygenases at chromosome 17p13.1: cloning, physical mapping, and expression. |journal=Genomics |volume=73 |issue= 3 |pages= 323-30 |year= 2001 |pmid= 11350124 |doi= 10.1006/geno.2001.6519

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