KMO (gene)

Kynurenine 3-monooxygenase (kynurenine 3-hydroxylase), also known as KMO, is a human gene.cite web | title = Entrez Gene: KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8564| accessdate = ]

PBB_Summary
section_title =
summary_text = Kynurenine 3-monooxygenase (KMO; EC 1.14.13.9) is an NADPH-dependent flavin monooxygenase that catalyzes the hydroxylation of the L-tryptophan metabolite L-kynurenine to form L-3-hydroxykynurenine. [supplied by OMIM] cite web | title = Entrez Gene: KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8564| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Stone TW, Darlington LG |title=Endogenous kynurenines as targets for drug discovery and development. |journal=Nature reviews. Drug discovery |volume=1 |issue= 8 |pages= 609-20 |year= 2002 |pmid= 12402501 |doi=
*cite journal | author=Aoyama N, Takahashi N, Saito S, "et al." |title=Association study between kynurenine 3-monooxygenase gene and schizophrenia in the Japanese population. |journal=Genes Brain Behav. |volume=5 |issue= 4 |pages= 364-8 |year= 2006 |pmid= 16716206 |doi= 10.1111/j.1601-183X.2006.00231.x
*cite journal | author=Gregory SG, Barlow KF, McLay KE, "et al." |title=The DNA sequence and biological annotation of human chromosome 1. |journal=Nature |volume=441 |issue= 7091 |pages= 315-21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727
*cite journal | author=Aoyama N, Takahashi N, Saito S, "et al." |title=Association study between kynurenine 3-monooxygenase gene and schizophrenia in the Japanese population. |journal=Genes Brain Behav. |volume= |issue= |pages= |year= |pmid= 16643513 |doi= 10.1111/j.1601-183X.2006.00231.x
*cite journal | author=Ligam P, Manuelpillai U, Wallace EM, Walker D |title=Localisation of indoleamine 2,3-dioxygenase and kynurenine hydroxylase in the human placenta and decidua: implications for role of the kynurenine pathway in pregnancy. |journal=Placenta |volume=26 |issue= 6 |pages= 498-504 |year= 2005 |pmid= 15950064 |doi= 10.1016/j.placenta.2004.08.009
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Halford S, Freedman MS, Bellingham J, "et al." |title=Characterization of a novel human opsin gene with wide tissue expression and identification of embedded and flanking genes on chromosome 1q43. |journal=Genomics |volume=72 |issue= 2 |pages= 203-8 |year= 2001 |pmid= 11401433 |doi= 10.1006/geno.2001.6469
*cite journal | author=Breton J, Avanzi N, Magagnin S, "et al." |title=Functional characterization and mechanism of action of recombinant human kynurenine 3-hydroxylase. |journal=Eur. J. Biochem. |volume=267 |issue= 4 |pages= 1092-9 |year= 2000 |pmid= 10672018 |doi=
*cite journal | author=Alberati-Giani D, Cesura AM, Broger C, "et al." |title=Cloning and functional expression of human kynurenine 3-monooxygenase. |journal=FEBS Lett. |volume=410 |issue= 2-3 |pages= 407-12 |year= 1997 |pmid= 9237672 |doi=

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