Acute myelomonocytic leukemia
- Acute myelomonocytic leukemia
Infobox_Disease
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ICDO = ICDO|9867|3
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MeshID = D015479
Acute myelomonocytic leukemia (AMMoL) is a form of acute myeloid leukemia which involves a proliferation of CFU-GM myeloblasts and monoblasts.
It is classified under "M4" in the French-American-British classification (FAB).[cite web |url=http://www.ucsfhealth.org/adult/medical_services/cancer/leukemia/conditions/aml/signs.html |title=Acute Myeloid Leukemia - Signs and Symptoms |format= |work=] ]It is classified under "AML, not otherwise classified" in the WHO classification.[cite web |url=http://www.emedicine.com/med/topic34.htm |title=eMedicine - Acute Myelogenous Leukemia : Article by Karen Seiter |format= |work=] ]Translocations have been observed.[cite journal |author=Yamamoto K, Nagata K, Tsurukubo Y, "et al" |title=Translocation (8;12)(q13;p13) during disease progression in acute myelomonocytic leukemia with t(11;19)(q23;p13.1) |journal=Cancer Genet. Cytogenet. |volume=137 |issue=1 |pages=64-7 |year=2002 |pmid=12377416 |doi= |url=http://linkinghub.elsevier.com/retrieve/pii/S0165460802005551] ]Progression from myelodysplastic syndrome has been reported.[cite journal |author=Zhang L, Alsabeh R, Mecucci C, "et al" |title=Rare t(1;11)(q23;p15) in therapy-related myelodysplastic syndrome evolving into acute myelomonocytic leukemia: a case report and review of the literature |journal=Cancer Genet. Cytogenet. |volume=178 |issue=1 |pages=42-8 |year=2007 |pmid=17889707 |doi=10.1016/j.cancergencyto.2007.06.012 |url=http://linkinghub.elsevier.com/retrieve/pii/S0165-4608(07)00389-5] ]ee also
* Juvenile myelomonocytic leukemia
References
External links
* [http://www.academic.marist.edu/~jzmz/topics/erythroleukemia/myelomono1.html Overview] at Marist College
* [http://www.med-ed.virginia.edu/courses/path/innes/wcd/myeloid1.cfm Histology] at University of Virginia
* [http://pathy.med.nagoya-u.ac.jp/atlas/doc/node46.html#SECTION00415000000000000000 Images] at Nagoya University
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