GM2 (ganglioside)

GM2 (ganglioside)

GM2 is a type of ganglioside.

It is associated with GM2 gangliosidoses (for example, Tay-Sachs disease.)cite journal |author=Guetta E, Peleg L |title=Rapid detection of fetal mendalian disorders: tay-sachs disease |journal=Methods Mol. Biol. |volume=444 |issue= |pages=147–59 |year=2008 |pmid=18425478 |doi=10.1007/978-1-59745-066-9_11 |url=http://dx.doi.org/10.1007/978-1-59745-066-9_11]

ee also

* Ganglioside GM2 activator protein

References

External links

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  • GM2 — can refer to: * General MIDI Level 2 * GM2 (ganglioside) …   Wikipedia

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  • GM2 activator protein — a sphingolipid activator protein that binds GM2 ganglioside and related glycosphingolipids and presents them to hexosaminidase A for cleavage; it is necessary for enzyme activity. Deficiency results in GM2 gangliosidosis, AB variant …   Medical dictionary

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  • Ganglioside — is a molecule composed of a glycosphingolipid (ceramide and oligosaccharide) with one or more sialic acids (e.g. n acetylneuraminic acid, NANA) linked on the sugar chain. The 60+ known gangliosides differ mainly in the position and number of NANA …   Wikipedia

  • Ganglioside GM2 activator protein — is (GM2 AP) is a lipid transfer protein that stimulates the enzymatic processing of gangliosides, and also T cell activation through lipid presentation.This protein binds molecules of ganglioside GM2, extracts them from membranes, and presents… …   Wikipedia

  • GM2-Aktivator — Bändermodell nach PDB  …   Deutsch Wikipedia

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